Results 21 to 30 of about 36,995 (262)
Safety and Health at Work, 2012 Malignant mesothelioma is an uncommon but rapidly fatal disease for which the principal aetiological agent is exposure to asbestos. Mesothelioma is of particular significance in Australia where asbestos use was very widespread from the 1950s until the ...
Ewan MacFarlane +3 more
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Synergistic cancer risk assessment from PM1 bound metals and PAHs in the Indo-Gangetic Region
Sustainable Chemistry for the Environment, 2023 The atmospheric particulate matter (PM) contains a significant amount of human carcinogens such as metals and Polycyclic Aromatic Hydrocarbons (PAHs).
Aman Deep Gupta +2 more
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The multitude and diversity of environmental carcinogens
Environmental Research, 2007 We have recently proposed that lifestyle-related factors, screening and aging cannot fully account for the present overall growing incidence of cancer. In order to propose the concept that in addition to lifestyle related factors, exogenous environmental factors may play a more important role in carcinogenesis than it is expected, and may therefore ...
Belpomme, Dominique +6 more
openaire +3 more sources
Occurrence of Carcinogens and their Potential Effects on Human Health – A Review
UMYU Scientifica JournalThe significant rise in cancer incidence and related deaths makes cancer one of the biggest threats to public health. Each year, there are about 10 million new cases of cancer and 6 million resultant deaths.
Oludare Oladipo Agboola +6 more
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Histone deacetylases (HDACs) in XPC gene silencing and bladder cancer
Journal of Hematology & Oncology, 2011 Bladder cancer is one of the most common malignancies and causes hundreds of thousands of deaths worldwide each year. Bladder cancer is strongly associated with exposure to environmental carcinogens.
Abrams Judith +3 more
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Epidemiological Research on Occupational and Environmental Carcinogens [PDF]
International Journal of Environmental Research and Public Health, 2021 The cancer risk associated with exposure to environmental and occupational carcinogens such as asbestos, benzene, radiation, or lifestyle carcinogens such as cigarette smoking depends on the entire history of exposure to the carcinogen, including the age of exposure and the time-varying intensity of exposure [...]
openaire +3 more sources
Molecular Oncology, EarlyView.BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi +11 more
wiley +1 more source
Sodium arsenite-induced DNA methylation alterations exacerbated by p53 knockout in MCF7 cells
HeliyonEpigenetic alterations are ubiquitous across human malignancies. Thus, functional characterization of epigenetic events deregulated by environmental pollutants should enhance our understanding of the mechanisms of carcinogenesis and inform preventive ...
Felicia Fei-Lei Chung +5 more
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Cytochrome P450 CYP1A1: wider roles in cancer progression and prevention
BMC Cancer, 2009 CYP1A1 is one of the main cytochrome P450 enzymes, examined extensively for its capacity to activate compounds with carcinogenic properties. Continuous exposure to inhalation chemicals and environmental carcinogens is thought to increase the level of ...
Tsatsakis Aristidis M +2 more
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Cells, 2022 Specific gene and miRNA expression patterns are potential early biomarkers of harmful environmental carcinogen exposures. The aim of our research was to develop an assay panel by using several miRNAs for the rapid screening of potential carcinogens.
Andras Tomesz +13 more
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