Environmental Carcinogenesis as a Stochastic Evolutionary Failure of Senescence-Control Systems [PDF]
Environmental carcinogenesis is traditionally explained by the accumulation of genetic alterations induced by exogenous carcinogens. However, most exposed cells do not undergo malignant transformation because intrinsic tumor-suppressive mechanisms limit ...
Jose-Ramon Blanco, Amancio Carnero
doaj +2 more sources
An approach to estimating the environmental burden of cancer from known and probable carcinogens: application to Ontario, Canada [PDF]
Background Quantifying the potential cancer cases associated with environmental carcinogen exposure can help inform efforts to improve population health.
Susan Lavinia Greco +8 more
doaj +2 more sources
Awareness of environmental carcinogens and cancer risk among Jordanians
Background In light of the existing body of scientific data, many substances are now recognized or reasonably assumed to be human carcinogens. Public knowledge about modifiable environmental carcinogens is regarded as a crucial first step in primary ...
Walaa B. El Gazzar +9 more
doaj +2 more sources
Epidemiological Research on Occupational and Environmental Carcinogens [PDF]
The cancer risk associated with exposure to environmental and occupational carcinogens such as asbestos, benzene, radiation, or lifestyle carcinogens such as cigarette smoking depends on the entire history of exposure to the carcinogen, including the age of exposure and the time-varying intensity of exposure [...]
Caterina Ledda
openaire +4 more sources
The multitude and diversity of environmental carcinogens
We have recently proposed that lifestyle-related factors, screening and aging cannot fully account for the present overall growing incidence of cancer. In order to propose the concept that in addition to lifestyle related factors, exogenous environmental factors may play a more important role in carcinogenesis than it is expected, and may therefore ...
Belpomme, Dominique +6 more
openaire +4 more sources
A signature-agnostic test for differences between tumor mutation spectra reveals carcinogen and ancestry effects [PDF]
Despite dozens of tools to identify mutational signatures in cancer samples, there is not an established metric for quantifying whether signature exposures differ significantly between two heterogeneous groups of samples.
Samuel F. M. Hart +3 more
doaj +2 more sources
Global and regional burden of cancer in 2016 arising from occupational exposure to selected carcinogens: a systematic analysis for the Global Burden of Disease Study 2016 [PDF]
OBJECTIVES: This study provides a detailed analysis of the global and regional burden of cancer due to occupational carcinogens from the Global Burden of Disease 2016 study.
GBD 2016 Occupational Carcinogens Collaborators +4 more
core +5 more sources
Chemopreventive roles of medicinal foods against environmental carcinogens-induced cancers [PDF]
Objective: Cancer remains the major cause of death globally apart from cardiovascular diseases. Behavioural and dietary risks could trigger up to 70% of new cancer cases in the next 20 years based on speculations.
J. Teibo +7 more
doaj +1 more source
Compliance with the legal limits set at the European level for the content of polycyclic aromatic hydrocarbons (PAH), which are harmful to human health and the environment, is of central importance for the recycling of rubber, particularly end-of-life ...
Stefan Hoyer +4 more
doaj +1 more source
Background Over 800 pesticides are registered for use in the United States. Human studies indicate concern that some pesticides currently in use in large quantities may also pose a carcinogenic hazard.
Pamela J. Schwingl +2 more
doaj +1 more source

