Results 91 to 100 of about 284,642 (297)
Enhancer Reprogramming Reveals the Tumorigenic Role of PTPRZ1 in Lung Squamous Cell Carcinoma
Advanced Science, EarlyView.Lung squamous cell cancer (LUSC) is deadly due to lack of good treatments. Here, multiomics techniques are applied to LUSC tumors and find thousands of cancer‐specific enhancers controlling key genes. Interestingly, the gene PTPRZ1 is identified as a critical oncogene driven by the LUSC‐acquired enhancers. PTPRZ1 is activated by MDK, fueling cancer via
Yong‐Qiang Ning +11 more
wiley +1 more source
The Carcinogenic Action of 4-Aminodiphenyl and 3:2'-Dimethyl-4-Aminodiphenyl [PDF]
, 1952 A. L. WALPOLE +2 more
openalex +1 more source
Advanced Science, EarlyView.It is shown that hepatic c‐Fos responds to feeding, altering de novo lipogenesis, glycolysis, and a wide range of steatosis‐associated metabolic signaling pathways. Obesogenic diets cause hepatic c‐Fos overexpression, insulin resistance, and the induction of metabolic reprogramming‐related genes.
Ao Li +8 more
wiley +1 more source
THE CARCINOGENICITY OF CERTAIN DERIVATIVES OF p-DIMETHYLAMINOAZOBENZENE IN THE RAT [PDF]
, 1948 James A. Miller, Elizabeth C. Miller
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Tumor Microenvironment‐Responsive Nanomedicines for Potentiating Cancer Immunotherapy
Advanced Science, EarlyView.Strategies for TME‐responsive Nanomaterials to Potentiate Cancer Immunotherapy. Abstract Immunotherapy has emerged as a transformative paradigm in oncology, yet its clinical efficacy remains constrained by the immunosuppressive tumor microenvironment and inadequate spatiotemporal control of existing modalities, resulting in suboptimal patient response ...
Qianqian Huang +7 more
wiley +1 more source
HygieneIn the European Union, Occupational Safety and Health legislation generally refers to European Regulation (CE) n. 1272/2008 to define and classify carcinogens of concern for occupational risk assessment and exposure assessment.
Carolina Zellino +9 more
doaj +1 more source
Innovative Approach to Recycle Lithium‐Ion Battery Electrolytes via Sequential Chemical Processes
Advanced Energy Materials, EarlyView.A chemical separation method is developed to recycle and purify nonaqueous electrolytes from spent lithium‐ion batteries. The new process consists of a sequence of precipitation in tandem with each distillation and solvent‐assisted vacuum extraction to obtain high‐quality electrolyte precursors.
Ting‐Wei Hsu +2 more
wiley +1 more source
JOINT ACTION OF A CHEMICAL CARCINOGEN AND A NEOPLASTIC VIRUS TO INDUCE CANCER IN RABBITS [PDF]
, 1951 Stanfield Rogers, Peyton Rous
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Advanced Energy Materials, EarlyView.Component‐level engineering in alkaline water electrolysis (AWE) is systematically analyzed, highlighting strategies in porous electrodes, bubble management, membranes, and flow fields to overcome mass‐transport bottlenecks. By linking microstructural design to multi‐scale ionic and gas transport, this Review establishes design principles that connect ...
Qian Zhang +8 more
wiley +1 more source
Advanced Energy and Sustainability Research, EarlyView.This study optimizes salinity gradient power generation using reverse electrodialysis (RED) by analyzing key operational parameters through factorial experiments and machine learning. Life cycle assessment reveals RED environmental impact and sustainability compared to other renewables, offering insights into future material choices and system ...
Younes Mohammadi +5 more
wiley +1 more source