Results 81 to 90 of about 282,417 (263)

Biological Water Dynamics and Entropy: A Biophysical Origin of Cancer and Other Diseases

open access: yesEntropy, 2013
This paper postulates that water structure is altered by biomolecules as well as by disease-enabling entities such as certain solvated ions, and in turn water dynamics and structure affect the function of biomolecular interactions.
Stephanie Seneff   +2 more
doaj   +1 more source

Eco‐Friendly Solvent System for Inkjet Deposition of Wide Bandgap Perovskite Solar Cells Enabling Tandem Integration

open access: yesAdvanced Science, EarlyView.
The fabrication of wide‐bandgap perovskite thin films via green solvents integrated with inkjet printing is developed. Controlled crystallization of the perovskite layer is achieved by optimizing ink formulation and additive engineering, enabling power conversion efficiencies above 17% for single junctions and 28% for perovskite/silicon tandem solar ...
Uma Kousalya Dangudubiyyam   +12 more
wiley   +1 more source

A New Switchable Zr12 Oxocluster Based Large Pore Metal–Organic Framework Functionalized With Spin Crossover Complexes for Acetic Acid Colorimetric Sensing

open access: yesAngewandte Chemie, EarlyView.
We present here (1)⊂MIP‐216(Zr), a new hybrid material composed of an FeII spin crossover complex (1) loaded in the pores of a new hydrophobic metal–organic framework (MIP‐216(Zr), that presents a high affinity toward acetic acid and acts as a highly sensitive colorimetric sensor of acetic acid vapor due to a spin state switching of the encapsulated ...
Emmelyne Cuza   +8 more
wiley   +2 more sources

Disrupting Helicobacter pylori Iron Homeostasis With Bismuth Nanodrug‐Mediated Nutritional Trap for Targeted Gastric Infection Therapy

open access: yesAdvanced Science, EarlyView.
A “nutritional trap” strategy centered on disrupting bacterial iron homeostasis is proposed. The synthesized Bi‐TP@FU (TBF) can target Helicobacter pylori, interfere with the bacterial iron uptake and utilization processes to disrupt its iron homeostasis, induce bacterial death, and meanwhile preserve the balance of the intestinal flora.
Tianye Fang   +13 more
wiley   +1 more source

Carcinogens and mutagens in Polish enterprises in 2022–2023

open access: yesMedycyna Pracy
Background The aim of the study is to present information on the occurrence of carcinogenic or mutagenic agents in Polish enterprises in 2022–2023, based on information from the Central Register of Data on Exposure to Carcinogenic, Mutagenic or ...
Katarzyna Konieczko   +4 more
doaj   +1 more source

Total Aflatoxin Contamination Level in Flour in Mongolia and Aflatoxin Intake

open access: yesCentral Asian Journal of Medical Sciences, 2016
Objectives: This study aimed to assess the total aflatoxin contamination level in flour, flour storage conditions, and the aflatoxin intake in Mongolia.
Gerelmaa Lkhaasuren   +4 more
doaj   +1 more source

Rewiring Pyroptosis to Potentiate Cancer Immunotherapy via a Gasdermin D Agonist Bypassing Caspase‐3

open access: yesAdvanced Science, EarlyView.
This work introduces a small‐molecule agonist, DIBDO, that bypasses Casp‐3 to directly trigger GSDMD‐mediated pyroptosis in tumors. Activated by glutathione, DIBDO generates singlet oxygen and molecular iodine, blocking Casp‐3 pathways and inducing immunogenic cell death.
Dan Zhao   +6 more
wiley   +1 more source

The process of cancer. Part I. The role of selected factors in the induction of carcinogenesis

open access: yesJournal of Education, Health and Sport, 2019
Summary Introduction and objective: Cancer arises from genetic and epigenetic changes in the cell. Indication of the direct causes of cancer is no doubt very difficult, because the process of carcinogenesis is a multi-level and multi-stage. Knowledge of
Sylwia Paulina Jopkiewicz
doaj  

Pyrazole‐Derived Antibacterial Compounds Effectively Treat Methicillin‐Resistant Staphylococcus Aureus Infections by Inhibiting Aspartate Transcarbamoylase

open access: yesAdvanced Science, EarlyView.
This study unveils a novel antibacterial mechanism against MRSA, in which the compound Py‐27 selectively targets and inhibits aspartate transcarbamoylase (ATCase), a key enzyme in pyrimidine synthesis. This inhibition disrupts DNA replication, induces oxidative damage, leading to potent bactericidal activity.
Xiaorong Yang   +11 more
wiley   +1 more source

Assessing biomarkers of exposure to carcinogens associated with combustible cigarettes, electronic cigarettes, and heated tobacco products: a systematic review and meta-analysis

open access: yesFrontiers in Pharmacology
IntroductionThere is growing global concern about the emissions of harmful and potentially harmful constituents (HPHCs) associated with electronic cigarette (EC) and heated tobacco product (HTP) use.
Yue Cao   +10 more
doaj   +1 more source

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