Results 91 to 100 of about 310,687 (304)

Aged ZnO Nanoparticles Promote Breast Cancer Lung Metastasis by Remodeling the Pulmonary Microenvironment Through the CXCL10/Wnt/β‐Catenin Axis

open access: yesAdvanced Science, EarlyView.
In summary, pulmonary exposure to ZnO NPs, particularly aged NPs, promotes breast cancer metastasis by remodelling the lung tumour microenvironment. Aged ZnO NPs enrich M2‐macrophages, MDSCs and activated CAFs to form an immunosuppressive metastatic niche. CXCL10 from these cells drives metastasis via Wnt/β‐catenin activation.
Yong Zhu   +8 more
wiley   +1 more source

ALTERATION OF RETROVIRUS INDUCED TRANSFORMATION BY CHEMICAL CARCINOGENS.

open access: yes, 1984
ALTERATION OF RETROVIRUS INDUCED TRANSFORMATION BY CHEMICAL ...
WAYNE WEBSTER. WILSON (7966412)
core   +3 more sources

Recent trends in the industrial use and emission of known and suspected carcinogens in Ontario, Canada

open access: yes, 2017
Background: In 2010, Ontario, Canada’s most populous province, implemented its Toxics Reduction Act, Ontario Regulation 455/09 (TRA), which requires four major manufacturing and mineral processing industry groups that already report ...
Catherine E. Slavik   +2 more
core   +1 more source

Histone Lactylation Drives WNK1 Expression to Promote Esophageal Squamous Cell Carcinoma Progression Through Histone H3 Ser10 Phosphorylation

open access: yesAdvanced Science, EarlyView.
In brief. Yan et al. demonstrated that the excess lactate produced by the enhanced glycolysis pathway in esophageal cancer can lactylate H3K23, H3K23la can be enriched in the WNK1 promoter region to promote WNK1 expression, thereby increasing the phosphorylation of the p‐H3 Ser10 site, and p‐H3S10 can be enriched in the AKT1 promoter region to promote ...
Mingyang Yan   +12 more
wiley   +1 more source

Genotype identification of the Human Papilloma Virus in cervicouterine lesions carrier patients

open access: yesRevista Electrónica Dr. Zoilo E. Marinello Vidaurreta, 2016
Background: during the last years there has been a high prevalence of women infected with genotypes of the human papilloma virus, considered as a high risk because of its high oncogenicity.Objective: to identify the genotypes of the human papilloma virus
Alexander Morales Fontaine   +3 more
doaj  

Mac‐2 Binding Protein Glycosylation Isomer (M2BPGi)–Based Risk Stratification Refined by Tumor Metabolic Activity in Hepatocellular Carcinoma

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
M2BPGi reflects background liver fibrosis and hepatic functional impairment. PET SUVmax reflects tumor metabolic aggressiveness. Their combination identifies a dual‐high subgroup with the poorest recurrence‐free and overall survival. ABSTRACT Aim To evaluate the prognostic significance of preoperative Mac‐2 binding protein glycosylation isomer (M2BPGi)
Kojiro Shirabe   +8 more
wiley   +1 more source

Principles of establishing occupational exposure limits for carcinogens in Poland and in other EU countries [PDF]

open access: yes, 2013
The principles of determining exposure limits for carcinogens adopted in Poland, the European Union and in other selected countries of the EC are discussed in this article.
Jolanta Skowroń   +3 more
core   +1 more source

Cannabis and tobacco smoke are not equally carcinogenic

open access: yesHarm Reduction Journal, 2005
More people are using the cannabis plant as modern basic and clinical science reaffirms and extends its medicinal uses. Concomitantly, concern and opposition to smoked medicine has occurred, in part due to the known carcinogenic consequences of smoking ...
Melamede Robert
doaj   +1 more source

Biological Water Dynamics and Entropy: A Biophysical Origin of Cancer and Other Diseases

open access: yesEntropy, 2013
This paper postulates that water structure is altered by biomolecules as well as by disease-enabling entities such as certain solvated ions, and in turn water dynamics and structure affect the function of biomolecular interactions.
Stephanie Seneff   +2 more
doaj   +1 more source

Nonmutagenic carcinogens induce intrachromosomal recombination in dividing yeast cells. [PDF]

open access: yes, 1993
A large number of animal and human carcinogens without apparent genotoxic activity exist (nonmutagenic carcinogens) that are difficult or impossible to detect with the currently used short-term tests.
R H Schiestl, Schiestl, RH
core   +1 more source

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