Results 61 to 70 of about 310,687 (304)

Determination of 1-chloro-2,3-epoxypropane in order to assess the working environment

open access: yesMedycyna Pracy, 2020
Background 1-Chloro-2,3-epoxypropane, known as epichlorohydrin (ECH), is a colorless liquid used in the production of epoxy resins, synthetic glycerine, elastomers, glycidyl ethers, surfactants, polyamide-epichlorohydrin resins and others ...
Anna Jeżewska   +2 more
doaj   +1 more source

EBV‐Driven ODC1 Upregulation Enhances Polyamine Anabolism to Promote Viral Replication and Cisplatin Resistance in Nasopharyngeal Carcinoma

open access: yesAdvanced Science, EarlyView.
EBV‑BZLF1 initiates ODC1‑driven polyamine anabolism that correlates with poor clinical prognosis in nasopharyngeal carcinoma. The ODC1–spermidine axis promotes viral replication, cell proliferation and innate immune evasion. Pharmacological inhibition of ODC1 rescues cisplatin sensitivity, establishing ODC1 as a viable therapeutic target for EBV ...
Yueshuo Li   +9 more
wiley   +1 more source

STUDY OF PLASMA AND CYTOSOLIC GLUTATHIONE IN CADMIUM TOXICITY

open access: yesGomal Journal of Medical Sciences, 2014
Background: Cadmium causes oxidative stress because this metal lacerate antioxidant defense system in intracellular as well as extra cellular compartments resulting in depletion of reduced glutathione or GSH contents in these areas.
Hashmat Ullah   +5 more
doaj  

Occupational exposure to welding fume in Australia: An online survey

open access: yesAustralian and New Zealand Journal of Public Health
Objective: This survey aimed to investigate exposure to welding fume in Australian workplaces and the use of protective and control measures among workers. Methods: Data were collected via a cross-sectional online survey of workers and employers involved
Lin Fritschi   +4 more
doaj   +1 more source

Histological and histochemical changes of the intestinal mucosa at the urothelial-enteric anastomotic site

open access: yesInternational Brazilian Journal of Urology, 2006
OBJECTIVE: The incorporation of bowel segments for urinary tract reconstruction may induce intestinal mucosal changes with the development of metabolic, nutritional, gastrointestinal and carcinogenic complications.
Marcos A. Castro   +4 more
doaj   +1 more source

Arsenic Methyltransferase and Methylation of Inorganic Arsenic

open access: yesBiomolecules, 2020
Arsenic occurs naturally in the environment, and exists predominantly as inorganic arsenite (As (III) and arsenate As (V)). Arsenic contamination of drinking water has long been recognized as a major global health concern. Arsenic exposure causes changes
Nirmal K. Roy, Anthony Murphy, Max Costa
doaj   +1 more source

Advances in Se Wide‐Bandgap Photovoltaics and TexSe1‐x SWIR Photodiodes

open access: yesAdvanced Science, EarlyView.
In this review, fundamental properties and current challenges in Se photovoltaics (PVs) for tandem and indoor PVs and TexSe1‐x alloys for short wave infrared photodiodes are discussed. A case is made for the practicality of elemental chalcogenide optoelectronics, and a pathway toward resolving the key challenges in these respective technologies is ...
Adam D. Alfieri, Deep Jariwala
wiley   +1 more source

Functionalization and Metal Ion Encapsulation Within a Triaxial Supramolecular Weave

open access: yesAngewandte Chemie, EarlyView.
The functionalization of a triaxially woven supramolecular weave was achieved. Pre‐assembly modification of the peptide‐perylene monoimide building block enabled facile and homogeneous introduction of acetyl, pivaloyl and thiophene moieties throughout the assembly without disrupting the woven structure.
Andreas Herdlitschka   +6 more
wiley   +2 more sources

Repurposing FDA‐Approved Drugs to Inhibit Fungal PPTases for Broad‐Spectrum Synergy

open access: yesAdvanced Science, EarlyView.
Fungal secondary metabolites serve as crucial virulence effectors; however, the potential of their biosynthetic pathways as antifungal targets remains inadequately comprehended. Repurposed FDA‐approved drugs inhibit fungal PPTase (essential for secondary metabolism) in vivo.
Zili Song   +7 more
wiley   +1 more source

Photoactivated Platinum Complexes: Targeting Membrane Proteins and Organelles for Precision Cancer Therapy

open access: yesAngewandte Chemie, EarlyView.
This review highlights an emerging anticancer approach integrating platinum agents into photodynamic therapy (PDT) and photoactivated chemotherapy (PACT) systems, further augmented by cancer cell membrane‐ and organelle‐targeting. By directing photoactivated platinum complexes from nontargeted distribution to cancer cells or defined subcellular sites ...
Shu Chen   +3 more
wiley   +2 more sources

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