An integrated in vitro carcinogenicity test that distinguishes between genotoxic carcinogens, non-genotoxic carcinogens, and non-carcinogens [PDF]
Chemical safety testing plays a crucial role in product and pharmacological development, as well as chemoprevention; however, in vitro genotoxicity safety tests do not always accurately predict the chemicals that will be in vivo carcinogens. If chemicals
Ume-kulsoom Shah +5 more
core +1 more source
The impacts of including information about the number of carcinogens in smoke on standardized cigarette packs in the UK [PDF]
Background: Since May 2017, standardised packaging has been mandatory in the UK, with packs required to display an ‘information message’ explaining that there are more than 70 carcinogens in tobacco smoke.
McNeill, Ann +7 more
core +1 more source
Decoding Synergistic Pathways in Bimetallic MOFs for Advanced Oxidation Processes
This review presents a unified framework linking metal pairing and framework design with electronic structure, redox cycling, oxidant activation, reactive‐species generation, and catalytic performance across photocatalytic and oxidant‐based BMOF‐AOPs. The resulting design principles guide the development of hydrolytically stable and efficient BMOFs for
Karim El‐Naggar +2 more
wiley +1 more source
Assessment of Cadmium (Cd) and Lead (Pb) Blood Concentration on the Risk of Endometrial Cancer
Background: Cadmium (Cd) and lead (Pb) are heavy metals with carcinogenic potential. Their increased concentration has been correlated with a risk of malignancies, including breast, lung, kidney, gastrointestinal, and gynecological cancers.
Kaja Michalczyk +7 more
doaj +1 more source
Listing occupational carcinogens
The occupational environment has been a most fruitful one for investigating the etiology of human cancer. Many recognized human carcinogens are occupational carcinogens.
Lakhani, R. +23 more
core +1 more source
Machine Learning for Green Solvents: Assessment, Selection and Substitution
Environmental regulations have intensified demand for green solvents, but discovery is limited by Solvent Selection Guides (SSGs) that quantify solvent sustainability. Training a machine learning model on GlaxoSmithKline SSG, a database of sustainability metrics for 10,189 solvents, GreenSolventDB is developed. Integrated with Hansen solubility metrics,
Rohan Datta +4 more
wiley +1 more source
Determination of 1-chloro-2,3-epoxypropane in order to assess the working environment
Background 1-Chloro-2,3-epoxypropane, known as epichlorohydrin (ECH), is a colorless liquid used in the production of epoxy resins, synthetic glycerine, elastomers, glycidyl ethers, surfactants, polyamide-epichlorohydrin resins and others ...
Anna Jeżewska +2 more
doaj +1 more source
ML Workflows for Screening Degradation‐Relevant Properties of Forever Chemicals
The environmental persistence of per‐ and polyfluoroalkyl substances (PFAS) necessitates efficient remediation strategies. This study presents physics‐informed machine learning workflows that accurately predict critical degradation properties, including bond dissociation energies and polarizability.
Pranoy Ray +3 more
wiley +1 more source
STUDY OF PLASMA AND CYTOSOLIC GLUTATHIONE IN CADMIUM TOXICITY
Background: Cadmium causes oxidative stress because this metal lacerate antioxidant defense system in intracellular as well as extra cellular compartments resulting in depletion of reduced glutathione or GSH contents in these areas.
Hashmat Ullah +5 more
doaj
Occupational exposure to welding fume in Australia: An online survey
Objective: This survey aimed to investigate exposure to welding fume in Australian workplaces and the use of protective and control measures among workers. Methods: Data were collected via a cross-sectional online survey of workers and employers involved
Lin Fritschi +4 more
doaj +1 more source

