Results 61 to 70 of about 354,109 (308)

A population-based study of glutathione-S-transferase M1, T1 and P1 genotypes [PDF]

open access: yes, 2008
A retrospective study on healthy, unrelated subjects was conducted in order to estimate population glutathione-S-transferases (GST) genotype frequencies in Slovak population of men and compare our results with already published data (GSEC project)^1^.
Duš   +6 more
core   +1 more source

Bacterial reduction of N-oxides of tobacco- specific nitrosamines (TSNA) [PDF]

open access: yes, 1996
1 Contrary to established metabolic pattern, a recent investigation of NNK metabolism produced in rat urine higher levels of 4-(methylnitrosamino)-1-(3-pyridyl)-1- butanone (NNK) and 4-(methylnitrosamino)-1-(3-pyri dyl)-1-butanol (NNAL) than their N ...
Calmels S.   +4 more
core   +1 more source

Carcinogenicity of saccharin. [PDF]

open access: yesEnvironmental Health Perspectives, 1978
Saccharin is carcinogenic for the urinary bladder in rats and mice, and most likely is carcinogenic in human beings. The neoplasms of the urinary bladder are malignant and invade and metastasize. Male rats are more susceptible to urinary bladder carcinogenesis than female rats. Rats exposed as fetuses develop neoplasms more readily than rats exposed as
openaire   +3 more sources

Malectin Alleviates Endoplasmic Reticulum Stress in Gestational Diabetes Mellitus via Glycoprotein Quality Control Mechanisms

open access: yesAdvanced Science, EarlyView.
Malectin alleviates high glucose‐induced ER stress and damage in placental trophoblasts, a function dependent on its six critical carbohydrate‐binding residues. In a GDM mouse model, administration of TAT‐Malectin ameliorated hyperglycemia and placental ER stress and prevented fetal macrosomia.
Jiahui Zhu   +12 more
wiley   +1 more source

Histological and histochemical changes of the intestinal mucosa at the urothelial-enteric anastomotic site

open access: yesInternational Brazilian Journal of Urology, 2006
OBJECTIVE: The incorporation of bowel segments for urinary tract reconstruction may induce intestinal mucosal changes with the development of metabolic, nutritional, gastrointestinal and carcinogenic complications.
Marcos A. Castro   +4 more
doaj   +1 more source

Determination of 1-chloro-2,3-epoxypropane in order to assess the working environment

open access: yesMedycyna Pracy, 2020
Background 1-Chloro-2,3-epoxypropane, known as epichlorohydrin (ECH), is a colorless liquid used in the production of epoxy resins, synthetic glycerine, elastomers, glycidyl ethers, surfactants, polyamide-epichlorohydrin resins and others ...
Anna Jeżewska   +2 more
doaj   +1 more source

Case-control study of arsenic in drinking water and lung cancer in California and Nevada. [PDF]

open access: yes, 2013
Millions of people are exposed to arsenic in drinking water, which at high concentrations is known to cause lung cancer in humans. At lower concentrations, the risks are unknown.
Balmes, John R   +5 more
core   +1 more source

Natural Products Inspired Scaffold Diversification Leads to Unnatural Molecular Warhead and Covalent Strategy to Modulating Protein Function through Electrophilic Bromine Transfer

open access: yesAdvanced Science, EarlyView.
We report a new thiolate‐reactive α,α‐gem‐dibromo lactam warhead that activates transcription factor Nrf2 and demonstrates anti‐inflammatory activities, which have implications in cancer, neurodegeneration, and cardiovascular diseases. RNA‐seq illuminated detailed transcriptional profiles, and chemical reactions with cysteine‐containing compounds ...
Beau R. Brummel   +16 more
wiley   +1 more source

STUDY OF PLASMA AND CYTOSOLIC GLUTATHIONE IN CADMIUM TOXICITY

open access: yesGomal Journal of Medical Sciences, 2014
Background: Cadmium causes oxidative stress because this metal lacerate antioxidant defense system in intracellular as well as extra cellular compartments resulting in depletion of reduced glutathione or GSH contents in these areas.
Hashmat Ullah   +5 more
doaj  

Occupational exposure to welding fume in Australia: An online survey

open access: yesAustralian and New Zealand Journal of Public Health
Objective: This survey aimed to investigate exposure to welding fume in Australian workplaces and the use of protective and control measures among workers. Methods: Data were collected via a cross-sectional online survey of workers and employers involved
Lin Fritschi   +4 more
doaj   +1 more source

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