Results 11 to 20 of about 352,926 (358)
Cadmium, carcinogen, co-carcinogen and anti carcinogen [PDF]
Indian Journal of Clinical Biochemistry, 2001 As a stress agent, inducing apoptosis and blocking it, Cd can have both helpful and harmful effects. The atmosphere is a thin envelope which makes the worid a global village. Cd is the most toxic metal in air. As both the first and second messenger of the stress response, it is synergistically toxic with all other stressors, including many other ...
Priyanka Tomar +3 more
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Oxidative Stress in the Carcinogenicity of Chemical Carcinogens [PDF]
Cancers, 2013 This review highlights several in vivo studies utilizing non-genotoxic and genotoxic chemical carcinogens, and the mechanisms of their high and low dose carcinogenicities with respect to formation of oxidative stress. Here, we survey the examples and discuss possible mechanisms of hormetic effects with cytochrome P450 inducers, such as phenobarbital, a-
Anna Kakehashi +3 more
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Nonmutagenic carcinogens induce intrachromosomal recombination in dividing yeast cells. [PDF]
, 1993 A large number of animal and human carcinogens without apparent genotoxic activity exist (nonmutagenic carcinogens) that are difficult or impossible to detect with the currently used short-term tests.
Schiestl, RH
core +2 more sources
Preventing hereditary cancers caused by opportunistic carcinogens [PDF]
, 2011 Objectives Previous studies reported inherited BRCA1/2 deficits appear to cause cancer by impairing normal protective responses to some carcinogens.
Bernard Friedenson
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Epidemiology, Biostatistics, and Public Health, 2022 Millions of people have tattoos. The systemic effects of tattoo colorants (TCs) are mostly unknown. Several tattoos are on the market, which contain carcinogenic compounds such as poly aromatic hydrocarbons compounds or carcinogenic aromatic amines.
Sabbioni, Gabriele, Hauri, Urs
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Cell transformation assays for prediction of carcinogenic potential: State of the science and future research needs [PDF]
, 2011 Copyright @ 2011 The Authors. This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0), which permits unrestricted non-commercial use ...
A. D. Scott +65 more
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Threshold in Carcinogenicity of Genotoxic Carcinogens [PDF]
Journal of Carcinogenesis & Mutagenesis, 2014 Nowadays the idea of threshold in the carcinogenicity of chemical carcinogens has attracted interest in the field of carcinogenesis. With genotoxic agents there is considerable experimental evidence in support of the idea. Here, we report on the low dose carcinogenicity in rats observed with heterocyclic amines contained in cooked food, 2-amino-3,8 ...
Hideki Wanibuchi +3 more
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Occupational cancers – Epidemiology and certification
Medycyna Pracy, 2018 The etiology of cancer is multifactorial. Malignant tumors caused by factors occurring in the work environment, classified as carcinogenic in humans, can be recognized as an occupational disease.
Marta Wiszniewska +6 more
doaj +1 more source
International Journal of Circumpolar Health, 2018 Objective: Foetuses and neonates of women who use tobacco are exposed to nicotine and tobacco-derived carcinogens. We determined the relationship between urine biomarkers of tobacco toxicant exposure postpartum and in the neonates of Alaska Native (AN ...
Neal L. Benowitz +10 more
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Supervised mutational signatures for obesity and other tissue-specific etiological factors in cancer
eLife, 2021 Determining the etiologic basis of the mutations that are responsible for cancer is one of the fundamental challenges in modern cancer research. Different mutational processes induce different types of DNA mutations, providing ‘mutational signatures ...
Bahman Afsari +12 more
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