Objective: Foetuses and neonates of women who use tobacco are exposed to nicotine and tobacco-derived carcinogens. We determined the relationship between urine biomarkers of tobacco toxicant exposure postpartum and in the neonates of Alaska Native (AN ...
Neal L. Benowitz +10 more
doaj +1 more source
Mutations in pathways depending on BRCA1 and BRCA2 may increase cancer risks from an environmental carcinogen [PDF]
Recently, the President’s Cancer Panel [2008-2009] protested that preventive action is not taken when uncertainty exists about potential harm from a chemical, because the US regulatory approach demands that a hazard be incontrovertibly ...
Bernard Friedenson
core +2 more sources
Assessing the carcinogenic potential of low-dose exposures to chemical mixtures in the environment: the challenge ahead. [PDF]
Lifestyle factors are responsible for a considerable portion of cancer incidence worldwide, but credible estimates from the World Health Organization and the International Agency for Research on Cancer (IARC) suggest that the fraction of cancers ...
Ab Hamid, Hasiah +173 more
core +11 more sources
Supervised mutational signatures for obesity and other tissue-specific etiological factors in cancer
Determining the etiologic basis of the mutations that are responsible for cancer is one of the fundamental challenges in modern cancer research. Different mutational processes induce different types of DNA mutations, providing ‘mutational signatures ...
Bahman Afsari +12 more
doaj +1 more source
Risk associated with the presence of mycotoxins (aflatoxins and ochratoxin A) in foodstuffs: the case of fermented fish (adjuevan) marketed in Abidjan (Côte d’Ivoire) Description of the subject.
Kouakou Gains Kpan Kpan +3 more
doaj +1 more source
Health effects of exposure to radon: implications of the radon bed mattress incident in Korea [PDF]
Radon is a naturally occurring radioactive material formed by the slow decay of uranium and thorium found in the earth’s crust or construction materials. Internal exposure to radon accounts for about half of the natural background radiation dose to which
Songwon Seo +6 more
doaj +1 more source
Preventing hereditary cancers caused by opportunistic carcinogens [PDF]
Objectives Previous studies reported inherited BRCA1/2 deficits appear to cause cancer by impairing normal protective responses to some carcinogens.
Bernard Friedenson
core +2 more sources
Scientific Ignorance and Reliable Patterns of Evidence in Toxic Tort Causation: Is There a Need for Liability Reform? [PDF]
As a first step to preserving the central aims of tort law, courts will need to recognize the wide variety of respectable, reliable patterns of evidence on which scientists themselves rely for drawing inferences about the toxicity of substances.
Cranor, Carl F., Eastmond, David A.
core +2 more sources
Review of selected methods for estimating risk from occupational exposure to carcinogenic substances
Assessing the expected level of cancer risk associated with occupational exposure to chemical substances is extremely important, as it forms the basis for the proper and safe organization of work in a company.
Małgorzata Kupczewska-Dobecka +2 more
doaj +1 more source
Mouse models of colorectal cancer. [PDF]
Colorectal cancer is one of the most common malignancies in the world. Many mouse models have been developed to evaluate features of colorectal cancer in humans. These can be grouped into genetically-engineered, chemically-induced, and inoculated models.
Koeffler, H Phillip +2 more
core +2 more sources

