Results 31 to 40 of about 19,658 (200)

Increased expression of 5-hydroxytryptamine(2A/B) receptors in idiopathic pulmonary fibrosis: a rationale for therapeutic intervention [PDF]

, 2010
Background Idiopathic pulmonary fibrosis (IPF) has a poor prognosis and limited responsiveness to available treatments. It is characterised by epithelial cell injury, fibroblast activation and proliferation and extracellular matrix deposition ...
Amarie, Oana Veronica, Dumitrascu, Rio, Eickelberg, Oliver, Grimminger, Friedrich, Königshoff, Melanie, Reiter, Rudolf, Schermuly, Ralph Theo, Seeger, Werner, Udalov, Sergey   +8 more
core   +1 more source

Primary Testicular Carcinoid Tumor presenting as Carcinoid Heart Disease

Indian Journal of Urology, 2015
Primary carcinoid tumors of the testis are very rare, and they seldom present with carcinoid syndrome. We report a hereto unreported instance, where a patient with a long-standing testicular mass presented with carcinoid heart disease, an uncommon form ...
Manjunath L Chikkaraddi, Sudeep Krishna, Manjunath Shetty   +2 more
doaj   +1 more source

A Rare Case of Carcinoid Constrictive Pericarditis

JACC: Case Reports, 2020
We describe a case of atypical carcinoid heart disease. A 62-year-old woman with well-differentiated neuroendocrine tumor metastatic to the liver and lymph nodes presented with recurrent unilateral pleural effusions and lower extremity edema ...
Teresa S. Wang, MD, Emily K. Bergsland, MD, Ruth Zhang, MD, Kai Ihnken, MD, Kirsten Tolstrup, MD   +4 more
doaj   +1 more source

Biochemical factors in the blood serum of neuroendocrine tumor patients with carcinoid syndrome

Успехи молекулярной онкологии, 2022
Introduction. Carcinoid syndrome is the most common functional syndrome in patients with neuroendocrine tumors. More than 40 biochemical factors are responsible for the manifestation of carcinoid syndrome, among which serotonin is the most important. The
N. V. Lyubimova, Yu. S. Timofeev, A. V. Lebedeva, A. V. Artamonova, I. S. Stilidi, N. E. Kushlinskii   +5 more
doaj   +1 more source

Chromogranin A: From Laboratory to Clinical Aspects of Patients with Neuroendocrine Tumors [PDF]

, 2018
Background. Neuroendocrine tumors (NETs) are characterized by having behavior and prognosis that depend upon tumor histology, primary site, staging, and proliferative index.
Baldelli, Roberto, Campana, Davide, Di Giacinto, Paola, Isidori, Andrea, Lania, Andrea, Lenzi, Andrea, Rizza, Laura, Rota, Francesca, Zuppi, Paolo   +8 more
core   +1 more source

Carcinoid heart disease revealed by cyanosis with both right and left valvular involvement: a case report

Journal of Medical Case Reports, 2018
Background Carcinoid heart disease is a frequent complication of carcinoid syndrome. It is related to the release by the carcinoid tumor and/or its metastases of bioactive substances such as serotonin.
Khadija Khay, Salim Arous, Tarik Bentaoune, Abdenasser Drighil, Rachida Habbal   +4 more
doaj   +1 more source

Carcinoid Heart Disease

Structural Heart, 2020
Carcinoid heart disease is seen in 50% of patients with carcinoid syndrome and is the main cause of morbidity and mortality.
Amin Sabet, Mina Haghighiabyaneh, Chirag Rajyaguru, Ajit Raisinghani, Daniel Kupsky, Anthony N. DeMaria   +5 more
  +5 more sources

Metabolic Signatures of Lung Cancer in Biofluids: NMR-Based Metabonomics of Blood Plasma [PDF]

, 2011
In this work, the variations in the metabolic profile of blood plasma from lung cancer patients and healthy controls were investigated through NMR-based metabonomics, to assess the potential of this approach for lung cancer screening and diagnosis.
Ana Gomes, Ana M. Gil, António S. Barros, Asiago V. M., Bathe O. F., Bell J. D., Brian J. Goodfellow, Brière J.-J., Carrola J., Cláudia M. Rocha, Daykin C. A., Dong J., Duarte I. F., Duarte I. F., Erol A., Fan T. W. M., Fiorenza A. M., Fiorenza A. M., Freedman D. S., Gao H., Gao H. C., Gu H. W., Haffner H. T., Heber D., Iola F. Duarte, Isabel M. Carreira, Joana Carrola, João Bernardo, Jordan K. W., Keun H. C., Kochhar S., Lai H.-S., Laiakis E. C., Lin L., Lina Carvalho, Liu M., Lokhov P. G., Ludwig C., Ma Y., MacIntyre D. A., Maeda J., Muntoni S., Naini A. B., Norton J. A., Okamoto N., Pirozynski M., Psychogios N., Qiu Y. P., Ritchie S. A., Rocha C. M., Sitter B., Spratlin J. L., Sreekumar A., Stringer K. A., Thysell E., Tiziani S., Travis W. D., Trygg J., Urayama S., Vitor Sousa, Xu Q. S., Xue R., Yin P., Zhang J. A., Zhang Z. Y., Zhou J., Zira A. N.   +66 more
core   +2 more sources

Carcinoid Right Heart Disease

Journal of Medical Cases, 2020
Carcinoid heart disease is an unusual cause of right heart failure. We present the case of a 53-year-old man with a history of metastatic carcinoid tumors originating from the appendix, status post-chemotherapy, and liver embolizations. The patient presented with a right-sided valvular disease with severe pulmonic valve regurgitation, right ventricle ...
Sanchez-Nadales, Alejandro, Celis-Barreto, Valentina, Anampa-Guzman, Andrea, Salazar-Leon, Mariani, Contreras-Chavez, Pamela   +4 more
openaire   +3 more sources

Telotristat ethyl in carcinoid syndrome: safety and efficacy in the TELECAST phase 3 trial [PDF]

, 2018
Telotristat ethyl, a tryptophan hydroxylase inhibitor, was efficacious and well tolerated in the phase 3 TELESTAR study in patients with carcinoid syndrome (CS) experiencing ≥4 bowel movements per day (BMs/day) while on somatostatin analogs (SSAs ...
Anthony, Lowell B., Benavent, Marta, Fleming, Douglas, Fleming, Rosanna, Garcia-Carbonero, Rocio, Gross, David J., Hörsch, Dieter, Jiang, Wenjun, Kassler-Taub, Kenneth, Kulke, Matthew K., Kunz, Pamela L., Lapuerta, Pablo, Pavel, Marianne, Perros, Petros, Srirajaskanthan, Raj, Warner, Richard R. P., Wason, Suman, Weickert, Martin O.   +17 more
core   +2 more sources