Results 91 to 100 of about 304,742 (351)

Short SULF1/SULF2 splice variants predominate in mammary tumours with a potential to facilitate receptor tyrosine kinase-mediated cell signalling [PDF]

, 2016
The relative roles of SULF1 and SULF2 enzymes in tumour growth are controversial, but short SULF1/SULF2 splice variants predominate in human mammary tumours despite their non-detectable levels in normal mammary tissue. Compared with the normal, the level
Dhoot, G K, Gill, R M S, Mehra, V, Milford, E   +3 more
core   +1 more source

Breast: Secretory ductal carcinoma [PDF]

Atlas of Genetics and Cytogenetics in Oncology and Haematology, 2011
Review on Breast: Secretory ductal carcinoma, with data on clinics, and the genes involved.
openaire   +2 more sources

Highly multiplexed digital PCR assay for simultaneous quantification of variant allele frequencies and copy number alterations of KRAS and GNAS in pancreatic cancer precursors

Molecular Oncology, EarlyView.
Combining melting curve analysis enhances the multiplexing capability of digital PCR. Here, we developed a 14‐plex assay to simultaneously measure single nucleotide mutations and amplifications of KRAS and GNAS, which are common driver genes in pancreatic cancer precursors. This assay accurately quantified variant allele frequencies in clinical samples
Junko Tanaka, Tatsuo Nakagawa, Yusuke Ono, Yoshio Kamura, Takeshi Ishida, Hidemasa Kawabata, Kenji Takahashi, Hiroki Sato, Andrew S. Liss, Yusuke Mizukami, Takahide Yokoi   +10 more
wiley   +1 more source

Infiltrating ductal carcinoma of breast presenting as areolar dermal lesion [PDF]

, 2012
Infiltrating ductal carcinoma is the most common form of invasive breast cancer. It accounts for 80% of all types of breast cancer. We report an unusual presentation of histologically proven case of infiltrating ductal carcinoma of breast presented ...
Afzal, Shaista, Khan, Shaista, Minhas, Khurram, Shafqat, Gulnaz   +3 more
core   +1 more source

Predicting invasive breast cancer versus DCIS in different age groups. [PDF]

, 2014
BackgroundIncreasing focus on potentially unnecessary diagnosis and treatment of certain breast cancers prompted our investigation of whether clinical and mammographic features predictive of invasive breast cancer versus ductal carcinoma in situ (DCIS ...
Alagoz, Oguzhan, Ayvaci, Mehmet US, Burnside, Elizabeth S, Chhatwal, Jagpreet, Kerlikowske, Karla, Munoz del Rio, Alejandro, Nassif, Houssam, Sickles, Edward A   +7 more
core   +1 more source

Ductal Carcinoma In Situ Biology, Biomarkers, and Diagnosis

Frontiers in Oncology, 2017
Ductal carcinoma in situ (DCIS) is an often-diagnosed breast disease and a known, non-obligate, precursor to invasive breast carcinoma. In this review, we explore the clinical and pathological features of DCIS, fundamental elements of DCIS biology ...
Kylie L. Gorringe, S. Fox
semanticscholar   +1 more source

Interplay of integrins and selectins in metastasis

Molecular Oncology, EarlyView.
Here we review the role of integrins and their interplay with selectins in metastasis. The efficacy of integrin‐targeted therapies may be reduced in tumors where metastasis relies heavily on selectins. In certain tumors, integrins and selectins exhibit a synergistic interaction during intraperitoneal dissemination.
Diana Maltseva, Ashot Nersisyan, Alexander Tonevitsky   +2 more
wiley   +1 more source

Effectiveness of triennial screening with clinical breast examination: 14‐years follow‐up outcomes of randomized clinical trial in Trivandrum, India

Cancer, Volume 129, Issue 2, Page 272-282, 15 January 2023., 2023
Abstract Background This study presents the preliminary results of a randomized controlled trial (RCT) initiated in January 2006 in India to evaluate the effectiveness of clinical breast examination (CBE) in reducing breast cancer mortality as compared to a no‐screening control group reported significant downstaging in the intervention group.
Kunnambath Ramadas, Partha Basu, Beela S. Mathew, Richard Muwonge, Muraleedharan Venugopal, Aparna M. Prakasan, Rafi Malu, Eric Lucas, Paul Augustine, Rari P. Mony, Somanathan Thara, Rengaswamy Sankaranarayanan   +11 more
wiley   +1 more source

Spectrum of Special Variants of Breast Carcinoma and Differentiated Ductal Carcinomas with their Immunohistochemistry Profile in a Tertiary Care Centre

Journal of Medical Sciences and Health
Background: Breast cancer is a diverse disease with varying characteristics in morphology, presentation, treatment, and prognosis. It constitutes 25% of cancers in Indian women.
N Manjula, C Jayanthi, S Srivani, Damodara Kumaran   +3 more
doaj   +1 more source

Adverse surgical outcomes in screen-detected ductal carcinoma in situ of the breast [PDF]

, 2014
Background: The Sloane Project is the largest prospective audit of ductal carcinoma in situ (DCIS) worldwide, with over 12000 patients registered between 2003 and 2012, accounting for 50% of screen-detected DCIS diagnosed in the UK over the period of ...
,, Ball, Graham, Clements, Karen, Dobson, Hilary, Evans, Andrew, Hanby, Andrew, Lawrence, Gill, Maxwell, Anthony, Pinder, Sarah E, Thomas, Jeremy, Thompson, Alastair, Wallis, Matthew   +11 more
core   +1 more source