Results 71 to 80 of about 1,379,743 (300)

Case Report: Ductal Carcinoma in Situ Within A Granulomatous Mastitis

European Journal of Breast Health, 2018
Granulomatous lobular mastitis is a rare chronic breast disease, firstly described by Kessler and Wolloch in 1972. In this article we present a 35-yearold patient with granulomatous lobular mastitis and in situ ductal carcinoma and discuss ...
Mine Özşen, Şahsine Tolunay, M. Şehsuvar Gökgöz   +2 more
doaj   +1 more source

Multi‐regional Organoid Biobank Reveals FAK‐ACSL1‐Driven Doxorubicin‐Resistance and Predictive Biomarkers in Breast Cancer

Advanced Science, EarlyView.
This study established a high‐quality organoid biobank derived from 68 tumor sites across 50 Chinese patients, elucidated the drug sensitivity‐based molecular subtyping in breast cancer, and revealed a novel mechanism of drug resistance mediated by the FAK‐ACSL1 pathway.
Hao Xu, Zhijun Qin, Jiapeng Yang, Baoyuan Zhang, Manqing Cao, Peng Wang, Zaiqi Wang, Jinghui Cheng, Lei Wang, Hong Liu, Hui Yang   +10 more
wiley   +1 more source

Coexistence of invasive ductal breast carcinoma and fibroadenoma

The Pan African Medical Journal, 2019
Fibroadenomas are the most common breast disease that occurs usually in young. The coexistence of an invasive ductal carcinoma and a fibroadenoma in the ipsilateral breast is extremely rare. We present the case of a 52 years woman, presented to us for an
Fatma Saadallah, Imen Bouraoui, Lamia Naija, Saida Sakhri, Ines Zemni, Jamel Ben Hassouna, Tarak Ben Dhieb, Hatem Bouzaiene, Khaled Rahal   +7 more
doaj   +1 more source

[Ductal carcinoma in situ of the breast].

Il Giornale di chirurgia, 2006
The Authors report their experience about 127 ductal carcinoma in situ (DCIS) of the breast. Guidelines for surgical treatment are: radiological or clinical diagnosis, tumor's extension, histological classification, grading and margin status. At the present the Authors prefer breast conserving surgery with tumor margin's study.
PROCACCINI, Eugenio, RUGGIERO, Roberto, DOCIMO, Giovanni, IOVINO, Francesco, PROCACCINI F., GILI S., LO SCHIAVO F.   +6 more
openaire   +2 more sources

Gut‐Liver Translocation of Bacteroides Uniformis Alleviates Advanced Metabolic Dysfunction‐Associated Steatotic Liver Disease by Suppressing Hepatocyte Ferroptosis via Propionic Acid Secretion

Advanced Science, EarlyView.
Systematic characterization of the liver‐resident microbiota in advanced metabolic dysfunction‐associated steatotic liver disease (MASLD) reveals a consistent depletion of Bacteroides uniformis (B. uniformis) in both hepatic and gut microbial communities. Oral gavage of B.
Haiyang Liu, Zun Fan, Zhen Liu, Lei Qin, Xin Zhao   +4 more
wiley   +1 more source

GM‐CSF Promotes Neutrophil PD‐L1 Expression Through the VEGFR‐2/STAT6/CSF2 Signaling Axis in Oral Squamous Cell Carcinoma

Advanced Science, EarlyView.
VEGFR‐2 signaling in OSCC activates Src–STAT6‐dependent CSF2 transcription, driving tumor‐derived GM‐CSF secretion. GM‐CSF programs neutrophils to express PD‐L1 through STAT5–mTOR/S6K signaling, suppressing cytotoxic CD8+ T cells. This pathway reveals a tumor–neutrophil immune checkpoint circuit that limits anti‐PD‐1 responsiveness in OSCC.
Fangxing Zhu, Yuanhe You, Yiyi Zhang, Yibin Dai, Xinyu Zhou, Yong Fu, Xi Lu, Yingying Huang, Zhihang Zhou, Ronghui Xia, Wutong Ju, Zhaoqi Yuan, Laiping Zhong, Tongchao Zhao   +13 more
wiley   +1 more source

Does shear wave ultrasound independently predict axillary lymph node metastasis in women with invasive breast cancer? [PDF]

, 2013
Shear wave elastography (SWE) shows promise as an adjunct to greyscale ultrasound examination in assessing breast masses. In breast cancer, higher lesion stiffness on SWE has been shown to be associated with features of poor prognosis.
Thomson, Kim, Petra Rauchhaus, Patsy Whelehan, Rauchhaus, Petra, Andrew Evans, Vinnicombe, Sarah, Michie, Caroline O, Caroline O. Michie, Kim Thomson, Purdie, Colin A, Whelehan, Patsy; id_orcid, Alastair Thompson, Jordan, Lee B., Sarah Vinnicombe, Lee B. Jordan, Evans, Andrew, Thompson, Alastair, Colin A. Purdie   +17 more
core   +1 more source

SemanticST: A Scalable Multi‐Contextual Graph Learning Framework for Uncovering Spatial Niches and Robust Multi‐Sample Integration in Spatial Transcriptomics

Advanced Science, EarlyView.
Technical limitations often let dominant signals overshadow rare cell types and fine‐grained heterogeneity in spatial transcriptomics. SemanticST, a graph neural network using multi‐semantic graph fusion and a novel min‐cut loss, recovers these subtle patterns.
Roxana Zahedi, Ahmadreza Argha, Nona Farbehi, Ivan Bakhshayeshi, Thantrira Porntaveetus, Youqiong Ye, Nigel H. Lovell, Hamid Alinejad‐Rokny   +7 more
wiley   +1 more source

Primary neuroendocrine carcinoma of the breast: report of 2 cases and literature review

Radiology Case Reports, 2017
Neuroendocrine tumors of the breast are very rare accounting for less than 0.1% of all breast cancers and less than 1% of all neuroendocrine tumors.
Fernando Collado-Mesa, MD, Jose M. Net, MD, Geetika A. Klevos, MD, Monica M. Yepes, MD   +3 more
doaj   +1 more source

Atypical ductal hyperplasia is a multipotent precursor of breast carcinoma [PDF]

, 2019
The current model for breast cancer progression proposes independent “low‐grade (LG) like” and “high‐grade (HG) like” pathways but lacks a known precursor to HG cancer.
Campbell, IG, Doyle, Maria, Kylie L Gorringe, Mann, GB, Hill, Prue, Mann, G. Bruce, David L Goode, Wajiha Sufyan, Magnus Zethoven, Miligy, IM, Murugasu, Anand, Emad A Rakha, Elder, K, Islam M Miligy, Green, Andrew R, Green, AR, Goode, DL, Thio, N, Semple, T, Stephen B Fox, Gorringe, KL, Prue Hill, Anand Murugasu, G Bruce Mann, Goode, David L., Campbell, Ian G., Ian G Campbell, Sufyan, W, Kader, T, David J Byrne, Rakha, Emad A, Andrew R Green, Byrne, DJ, Thio, Niko, Gorringe, Kylie L., Pang, JMB, Jia‐Min B Pang, Sufyan, Wajiha, Murugasu, A, Hill, P, Elder, Kenneth, Tanjina Kader, Semple, Timothy, Rakha, EA, Kenneth Elder, Maria Doyle, Zethoven, M, Fox, Stephen B., Kader, Tanjina, Doyle, M, Byrne, David J., Zethoven, Magnus, Pang, Jia-Min B., Miligy, Islam M, Niko Thio, Timothy Semple, Fox, SB   +56 more
core   +1 more source