Results 91 to 100 of about 105,263 (261)

Targeting the intratumoral microbiota to overcome cancer immunotherapy resistance

Interdisciplinary Medicine, EarlyView.
This review delineates the mechanisms of intratumoral microbiota in cancer immunotherapy resistance, and offers strategies for microbiota‐targeted precision immunotherapy. Abstract Cancer remains a significant global health threat. The tumor microenvironment (TME) is a sophisticated ecological niche that exerts a pivotal effect on treatment outcomes ...
Bufu Tang, Tong Jiang, Yaling Lin, Wei Zhang, Hongjie Fan, Minjie Yang, Bingzhe Li, Yaozu Liu, Changyu Li, Xuran Jin, Wen Zhang, Zhiping Yan, Qianqian Zhao, Xuefeng Kan, Xudong Qu   +14 more
wiley   +1 more source

DIVERSITY OF HISTOLOGICAL VARIANTS OF BREAST CANCER: A TERTIARY CARE HOSPITAL EXPERIENCE IN KARACHI, PAKISTAN

Pakistan Armed Forces Medical Journal, 2020
Objective: To determine the prevalence of histological subtypes of breast cancer and its association with age, molecular subtype, menopausal status, parity, obesity and tumor grade. Study Design: Prospective, observational study. Place and Duration
Shumyla Beg, Ghulam Haider, Ejaz Khan, Aisha Shahid, Paras Memon, Raja Rahul, Bhunisha Pavan, Kiran Abbas   +7 more
doaj  

Serum Midkine as a Biomarker for Hepatocellular Carcinoma Treatment Response and Prognostication

Journal of Clinical Laboratory Analysis, EarlyView.
Up‐to‐date, tumor markers are considered more helpful in the evaluation of treatment response and prognostication rather than diagnosis. Identifying a valid biomarker to help clinical management of hepatocellular carcinoma (HCC) is still a challenge, especially the alpha‐fetoprotein (AFP) negative HCC. This study evaluated the efficacy of serum Midkine
Yanfang Luo, Qiuwei Lu, Jing Huang, Liejun Jiang   +3 more
wiley   +1 more source

Omission of Sentinel Lymph Node Biopsy in Breast Cancer: A Real‐World Validation of the Patient Populations of the SOUND and INSEMA Trials

Journal of Surgical Oncology, EarlyView.
ABSTRACT Background Treatment guidelines recommending omission of axillary surgery in breast cancer are largely based on the SOUND and INSEMA trials. However, the extent to which their study populations represent real‐world patients remains unclear.
Tia Puiras, Eeva Juhanoja, Anselm Tamminen   +2 more
wiley   +1 more source

Consultoria em patologia cirúrgica mamária: variabilidade interobservador no diagnóstico de lesões proliferativas intraductais atípicas Consultation in breast surgical pathology: interobserver diagnostic variability of atypical intraductal proliferative lesions

Revista Brasileira de Ginecologia e Obstetrícia, 2013
OBJETIVO: Avaliar a concordância nos diagnósticos histopatológicos de lesões mamárias proliferativas intraductais entre patologistas gerais e especialistas em patologia mamária.
Amanda Arantes Perez, Débora Balabram, Marcio de Almeida Salles, Helenice Gobbi   +3 more
doaj  

Case Report: Sneaky DCIS-like invasive ductal carcinoma of the breast in the setting of extensive DCIS

Frontiers in Medicine
In most cases, invasive ductal carcinoma (IDC) of the breast is identifiable when it presents with classic infiltrative growth patterns. However, a subset of IDC can present in a very sneaky way, significantly mimicking the appearance of ductal carcinoma
Chong Chen, Chong Chen, Yateng Tie, Xinjuan Zhang, Niuniu Hou, Niuniu Hou, Yun Song, Yun Song, Dong Ren, Dong Ren   +9 more
doaj   +1 more source

Ductal carcinomain situ in breast carcinogenesis

The Journal of Pathology, 1999
Evidence is mounting that ductal carcinoma in situ (DCIS) is a direct precursor of invasive breast cancer. Recent molecular biological and cytogenetic studies have revealed chromosomal gains and losses involved in breast carcinogenesis. This editorial discusses how the gains and losses on the different chromosomes fit into previously defined ...
openaire   +4 more sources

Management of Satellite Lesions in Hepatocellular Carcinoma: An Updated Review

Journal of Surgical Oncology, EarlyView.
ABSTRACT Satellite lesions, defined as microscopic or small macroscopic tumor nodules within 2 cm of a primary hepatocellular carcinoma (HCC), represent early intrahepatic dissemination and are strongly associated with aggressive tumor biology.
Andy Tran, Mohammed O. Suraju, Ihuoma Tasie, Abdelrahman K. Abdalla, Hassan Aziz   +4 more
wiley   +1 more source

EVALUATION OF SOME SERUM ENZYMES LEVELS IN BREAST CANCER PATIENTS

The Iraqi Journal of Medical Sciences, 2004
Background: Breast cancer is the most common gynecological malignancy in many parts of the world. It is the major cause of death for women, and its occurrence has a particular relevance to women's health worldwide.
doaj   +1 more source