Results 101 to 110 of about 1,379,743 (300)

Flowcytometric Analysis of Tumor Associated Macrophages in Invasive Ductal Carcinoma of Breast [PDF]

Background: Invasive ductal carcinoma is the most common type of breast cancer in Iran. Impaired immune responses occur frequently in cancer patients, but the mechanisms of the induced immune defects remain poorly understood.
حسن, زهیر محمد, روانگرد, فاطمه, فرازمند, سوسن, امانی, داور, کریم زاده, مجتبی   +4 more
core  

CXCL3 Antagonism Reverses Systemic Antitumor Immune Memory Impairment Associated With High Tumor Burden and Sensitizes Anti‐PD‐1 Therapy

Advanced Science, EarlyView.
This study reveals that large tumors secrete more chemokine CXCL3, which recruits immunosuppressive neutrophils to the periphery, thereby impairing the activation and memory of systemic tumor‑reactive CD8+ T cells. CXCL3 antagonism restores systemic immune memory and enhances the antitumor efficacy of anti‑PD‑1 therapy, offering a potential strategy to
Ji Wang, Xinyu Tang, Zeju Li, Qi Qi, Chang Sun, Wen Sun, Weiya Zhang, Yue Yin, Ya Deng, Peiwen Ling, Yifan Xu, Guangshun Sun, Yi Ren, Hong Pan, Shui Wang, Wenbin Zhou   +15 more
wiley   +1 more source

Gallbladder metastasis in invasive ductal breast cancer with concurrent gallstones and gallbladder carcinoma

Discover Oncology
The gallbladder is an uncommon location for tumor metastases. Breast cancer seldom spreads to the gallbladder, although melanoma and renal cell tumors typically do.
Rujuan Wang, Feng Zhao, Tao Yan, Yongtian Li, Danqing Cheng, Wenping Wang, Chongyue Tian, Hao Yu   +7 more
doaj   +1 more source

Nanofabricated Biomaterials Model Tumor Extracellular Matrix Topography

Advanced NanoBiomed Research, EarlyView.
The unique structure and composition of the tumor microenvironment and its associated extracellular matrix (ECM) exert profound effects on cancer cell behavior that are difficult to model in vitro. This perspective discusses the utility of nanofabricated biosubstrates, such as the novel collagen‐coated nanogrooved array, for recapitulating the ...
Vic Zamloot, JinSeok Park
wiley   +1 more source

High TTK expression drives primary cilia deficiency in ductal carcinomas: An integrated analysis based on TCGA/GTEx data

生物医学转化
Objective To investigate the mechanism underlying primary cilia loss in ductal carcinomas (breast, pancreatic, and cholangiocarcinoma). Methods Transcriptomic data from ductal carcinomas (breast ductal carcinoma, pancreatic ductal adenocarcinoma ...
Li Zhengyang, Yu Hongwei, Zhao Huiming, Pan Feifei, Liu Haotian, Wu Lele, Shi Wengui, Jiao Zuoyi   +7 more
doaj   +1 more source

Secretory Breast Carcinoma: A Case Report with MRI Findings

대한영상의학회지, 2019
Secretory carcinoma of the breast is an extremely rare, clinically and histologically distinct variant of invasive ductal carcinoma, with an indolent growth pattern and a more favorable prognosis than that of typical ductal carcinoma.
Sung Hee Shin, Hye Jung Kim, Won Hwa Kim, Hoseok Lee, Wan Wook Kim, Ji Young Park, Dong Sug Kim   +6 more
doaj   +1 more source

Characterization of the extracellular matrix from human and dog umbilical cords

The Anatomical Record, EarlyView.
Abstract The extracellular matrix is important for maintaining tissue morphogenesis and homeostasis; it can also be used as a biomaterial for the production of biological scaffolds. Particularly, the umbilical cord has shown potential in the production of scaffolds for small‐diameter vessels.
Ana Carla Mendonça, Roberta Losi Guembarovski, Carlos Alberto Miqueloto, Alda Fiorina Maria Losi Guembarovski, Caio Garcia Barbosa da Silva, Laís Capelasso Lucas Pinheiro, Phelipe Oliveira Favaron   +6 more
wiley   +1 more source

Exposure‐adjusted safety and efficacy of GLP‐I and GLP‐1/GIP receptor agonists compared with non‐GLP‐I for weight management and type 2 diabetes: Based on FDA medical and statistical reports of 34 280 safety and 36 312 efficacy subjects

British Journal of Clinical Pharmacology, EarlyView.
Aims This work aimed to contextualize glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) and glucose‐dependent insulinotropic polypeptide (GIP) receptor agonists safety and efficacy regarding weight management (WM); we analysed Food and Drug Administration (FDA) Medical Reviews to analyse 14 medications using patient‐exposure year normalization and ...
Aishwarya Prasad, Anshu Arora, Arun Arora, Jeena Vaid, Arif Khan   +4 more
wiley   +1 more source

Evaluation of carbonic anhydrase IX as a therapeutic target for inhibition of breast cancer invasion and metastasis using a series of in vitro breast cancer models [PDF]

, 2015
This research was financed in part by a Grant of the 7th Framework Program of the European Union (METOXIA project; HEALTH‐F2‐2009‐222741) and the NGI Pre- Seed grant (NWO n° 93613002).Triple negative, resistant or metastatic disease are major factors in ...
Kunkler, Ian H., Jarman, Edward J, Kunkler, Ian, Pavathaneni, Nanda- Kumar, Meehan, James, Jarman, Edward, Ward, Carol, Harrison, David James, Langdon, Simon P., Dixon, J. Michael, Um, In Hwa, Supuran, Claudiu, Lambin, Philippe, Winum, Jean-Yves, Um, Inhwa, Dixon, MIchael, Supuran, Claudiu Trandafir, Renshaw, Lorna, Harrison, David J, Dubois, Ludwig, Langdon, Simon, Thomas, Jeremy, Mullen, Peter, Kay, Charlene, Jarman, Edward J., Kay, Charlene; id_orcid, Supuran, Claudiu T, Harrison, David, Pavathaneni, Nanda-Kumar, Thomas, Jeremy S., Harrison, David J.   +30 more
core   +2 more sources