Results 51 to 60 of about 304,742 (351)

Unusual case of Paget disease of the nipple diagnosed by nipple scraping cytology [PDF]

, 2020
Paget disease of the nipple is a rare presentation of breast cancer. It is sometimes mistaken for a benign skin condition of the nipple and surrounding areola, which can significantly delay the diagnosis and treatment.
Herbst, Ewa, McIntosh, Violet Merle, Tismenetsky, Mikhail   +2 more
core   +1 more source

Matrix Metalloproteinase 13 Is Induced in Fibroblasts in Polyomavirus Middle T Antigen-Driven Mammary Carcinoma without Influencing Tumor Progression [PDF]

, 2008
Matrix metalloproteinase (MMP) 13 (collagenase 3) is an extracellular matrix remodeling enzyme that is induced in myofibroblasts during the earliest invasive stages of human breast carcinoma, suggesting that it is involved in tumor progression.
Askautrud, Hanne A., Christensen, Ib J., Edwards, Dylan R., Egeblad, Mikala, Lund, Leif R., Nielsen, Boye S., Pedersen, Tanja X., Pennington, Caroline J., Rank, Fritz, Werb, Zena   +9 more
core   +3 more sources

Ductal carcinoma in situ: to treat or not to treat, that is the question

British Journal of Cancer, 2019
Ductal carcinoma in situ (DCIS) now represents 20–25% of all ‘breast cancers’ consequent upon detection by population-based breast cancer screening programmes.
M. Seijen, E. Lips, A. Thompson, S. Nik-Zainal, A. Futreal, E. Hwang, E. Verschuur, J. Lane, J. Jonkers, D. Rea, J. Wesseling, J. Wesseling, Precision team   +12 more
semanticscholar   +1 more source

Current updates of CRISPR/Cas9‐mediated genome editing and targeting within tumor cells: an innovative strategy of cancer management

Cancer Communications, Volume 42, Issue 12, Page 1257-1287, December 2022., 2022
Abstract Clustered regularly interspaced short palindromic repeats‐associated protein (CRISPR/Cas9), an adaptive microbial immune system, has been exploited as a robust, accurate, efficient and programmable method for genome targeting and editing. This innovative and revolutionary technique can play a significant role in animal modeling, in vivo genome
Khaled S. Allemailem, Mohammed A Alsahli, Ahmad Almatroudi, Faris Alrumaihi, Fahd Khaleefah Alkhaleefah, Arshad Husain Rahmani, Amjad Ali Khan   +6 more
wiley   +1 more source

Pathomimetic avatars reveal divergent roles of microenvironment in invasive transition of ductal carcinoma in situ [PDF]

, 2017
The breast tumor microenvironment regulates progression of ductal carcinoma in situ (DCIS) to invasive ductal carcinoma (IDC). However, it is unclear how interactions between breast epithelial and stromal cells can drive this progression and whether ...
Aggarwal, Neha, Anbalagan, Arulselvi, Cavallo-Medved, Dora, Chalasani, Anita, Chen, Xuequn, E. Franco, Omar E., Hayward, Simon W., Ji, Kyungmin, Mattingly, Raymond R., Sameni, Mansoureh, Sloane, Bonnie F.   +10 more
core   +3 more sources

Independent predictors of breast malignancy in screen-detected microcalcifications: biopsy results in 2545 cases [PDF]

, 2011
Background: Mammographic microcalcifications are associated with many benign lesions, ductal carcinoma in situ (DCIS) and invasive cancer. Careful assessment criteria are required to minimise benign biopsies while optimising cancer diagnosis.
Downey, P., Farshid, G., Gill, P., Pieterse, S., Sullivan, T.   +4 more
core   +2 more sources

A Multigene Expression Assay to Predict Local Recurrence Risk for Ductal Carcinoma In Situ of the Breast

Journal of the National Cancer Institute, 2013
Background For women with ductal carcinoma in situ (DCIS) of the breast, the risk of developing an ipsilateral breast event (IBE; defined as local recurrence of DCIS or invasive carcinoma) after surgical excision without radiation is not well defined by ...
L. Solin, R. Gray, F. Baehner, S. Butler, L. Hughes, C. Yoshizawa, D. Cherbavaz, S. Shak, D. Page, G. Sledge, N. Davidson, J. Ingle, E. Perez, W. Wood, J. Sparano, S. Badve   +15 more
semanticscholar   +1 more source

Protein expression of c-erbB-2 and p53 in normal ducts, ductal carcinoma in situ and invasive carcinoma of the same breast

São Paulo Medical Journal
CONTEXT AND OBJECTIVE: Breast cancer is thought to derive from progressively aberrant, non-invasive breast lesions, but it is not known exactly how invasive breast cancer develops from these lesions.
Marcus Vinicius Martins de Menezes, Anna Letícia Oliveira Cestari, Orlando Almeida, Marcelo Alvarenga, Glauce Aparecida Pinto, Maria Salete Costa Gurgel, Gustavo Antônio de Souza, Luiz Carlos Zeferino   +7 more
doaj   +1 more source

Expression and intracellular localization of FKHRL1 in mammary gland neoplasms. [PDF]

, 2004
FKHRL1 (FOXO3a), a member of the Forkhead family of genes, has been considered to be involved in the development of breast tumors; however, the in vivo expression and activation status of FKHRL1 in breast tumors still remains unclear.
Akagi, Tadaatsu, Hayashi, Kazuhiko, Jin, Gui-Shan, Kondo, Eisaku, Liu, Yi-Xuan, Miyake, Takayoshi, Shibata, Masao, Takashima, Takako, Yoshino, Tadashi   +8 more
core   +1 more source

Ductal carcinoma in situ of the male breast [PDF]

Cancer, 1994
Ductal carcinoma in situ (DCIS) of the male breast is an uncommon disease, accounting for approximately 7% of all male breast carcinomas. Compared with invasive carcinomas of the breast, the prognosis associated with DCIS in men is excellent; however, clinical features, pathology, and treatment of this disease are not well defined in the literature ...
Jo Buyske, J. Lawrence Munson, Gasan Mackarem, Megha G. Joshi, Mauricio G. Camus, Leonard J. Barbarisi, Laura E. Sanders, Arthur K. C. Lee, Ricardo L. Rossi, Kevin S. Hughes   +9 more
openaire   +3 more sources