Results 61 to 70 of about 304,742 (351)

IL-6 triggers malignant features in mammospheres from human ductal breast carcinoma and normal mammary gland.

open access: yesJournal of Clinical Investigation, 2007
High serum levels of IL-6 correlate with poor outcome in breast cancer patients. However, no data are available on the relationship between IL-6 and mammary stem/progenitor cells, which may fuel the genesis of breast cancer in vivo.
P. Sansone   +11 more
semanticscholar   +1 more source

A Deep Analysis of Transfer Learning Based Breast Cancer Detection Using Histopathology Images [PDF]

open access: yesarXiv, 2023
Breast cancer is one of the most common and dangerous cancers in women, while it can also afflict men. Breast cancer treatment and detection are greatly aided by the use of histopathological images since they contain sufficient phenotypic data. A Deep Neural Network (DNN) is commonly employed to improve accuracy and breast cancer detection.
arxiv  

Clinical-pathological features of an occult mixed mucinous male breast cancer. a case report [PDF]

open access: yes, 2017
Mucinous carcinoma of the male breast is an uncommon malignant breast neoplasm and its diagnoses remain difficult. It is probably due to such a low rate of breast cancer cases that men tend to be diagnosed at an older age than women and with a later ...
Bonifacino, Adriana   +7 more
core   +1 more source

Association of Radiotherapy With Survival in Women Treated for Ductal Carcinoma In Situ With Lumpectomy or Mastectomy

open access: yesJAMA Network Open, 2018
Key Points Question Is adjuvant radiation associated with a reduction in breast cancer mortality in patients treated for ductal carcinoma in situ? Findings Using a matched approach in a large cohort of patients treated for ductal carcinoma in situ ...
V. Giannakeas, V. Sopik, S. Narod
semanticscholar   +1 more source

Decoding the dual role of autophagy in cancer through transcriptional and epigenetic regulation

open access: yesFEBS Letters, EarlyView.
Transcriptional and epigenetic regulation controls autophagy, which exerts context‐dependent effects on cancer: Autophagy suppresses tumorigenesis by maintaining cellular homeostasis or promotes tumor progression by supporting survival under stress. In this “In a Nutshell” article, we explore the intricate mechanisms of the dual function of autophagy ...
Young Suk Yu, Ik Soo Kim, Sung Hee Baek
wiley   +1 more source

Atypical Ductal Hyperplasia at the Margin of Lumpectomy Performed for Early Stage Breast Cancer: Is there Enough Evidence to Formulate Guidelines? [PDF]

open access: yes, 2012
Background. Negative margins are associated with a reduced risk of ipsilateral breast tumor recurrence (IBTR) in women with early stage breast cancer treated with breast conserving surgery (BCS).
Baker, Jennifer L   +2 more
core   +3 more sources

Unique clinicopathological features of metaplastic breast carcinoma compared with invasive ductal carcinoma and poor prognostic indicators

open access: yesWorld Journal of Surgical Oncology, 2013
BackgroundMetaplastic breast carcinoma is a rare aggressive malignant neoplasm. The purposes of this study are to review the pathologic features and clinical outcomes of metaplastic breast carcinoma compared to invasive ductal carcinoma and to evaluate ...
Yanni Song   +12 more
semanticscholar   +1 more source

Autophagy in cancer and protein conformational disorders

open access: yesFEBS Letters, EarlyView.
Autophagy plays a crucial role in numerous biological processes, including protein and organelle quality control, development, immunity, and metabolism. Hence, dysregulation or mutations in autophagy‐related genes have been implicated in a wide range of human diseases.
Sergio Attanasio
wiley   +1 more source

Recurrent Invasive Ductal Breast Carcinoma Presenting as Primary Adrenal Insufficiency with Adrenal Crisis

open access: yesAACE Clinical Case Reports, 2020
: Objective: We report the first case of recurrent ductal breast carcinoma presenting as primary adrenal insufficiency. Methods: We describe a patient who developed a recurrence of invasive ductal breast carcinoma which went undetected until the patient
Mitha Madhava Naik, MD   +2 more
doaj  

The Study of BRCA1 and BRCA2 Gene Mutations in Benign and Malignant Lesions of the Breast

open access: yesSokoto Journal of Medical Laboratory Science, 2023
Understanding the role of BRCA 1 and BRCA2 gene mutations is critical in the study of breast carcinogenesis. The aim was to study was to investigate BRCA | and BRCA2 gene mutations in benign and malignant lesions of the breast.
Ekundina Victor Olukayode , Unuigbokhai Ayomide Olohigbe , Wilson Serbia Princess
doaj  

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