Results 11 to 20 of about 8,031 (177)

Goniothalamin as a Styryl-Lactone Toxicophore in Cancer Models: Electrophile-Driven DNA Damage, Reactive Oxygen Species-Endoplasmic Reticulum Stress Signaling and Detoxification-Relevant Safety Considerations. [PDF]

J Biochem Mol Toxicol
Goniothalamin (GTN) exerts anticancer effects by promoting reactive oxygen species (ROS) generation, glutathione (GSH) depletion, DNA damage, endoplasmic reticulum (ER) stress, and mitochondrial dysfunction. These interconnected events trigger apoptosis, necroptosis, anoikis, and autophagy, while modulating mitogen‐activated protein kinase (MAPK ...
Joković N, Pešić S, Novaković M, Krstić AD, Setzer WN, Sharifi-Rad J, Calina D.   +6 more
europepmc   +2 more sources

Blood-based proteomic profiling reveals context-dependent changes in BCL2-associated signaling during taxane therapy in breast cancer patients. [PDF]

FEBS Open Bio
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Munshani S, Ibrahim EY, Rodwin RL, Ferrucci LM, Blenman K, Lustberg M, Ehrlich BE.   +6 more
europepmc   +2 more sources

Hyperbolastic modeling of tumor growth with a combined treatment of iodoacetate and dimethylsulphoxide

BMC Cancer, 2010
Background An understanding of growth dynamics of tumors is important in understanding progression of cancer and designing appropriate treatment strategies.
Bursac Zoran, Tabatabai Mohammad A, Eby Wayne M   +2 more
doaj   +1 more source

Growth Inhibition and Apoptosis of Ehrlich Ascites Carcinoma Cells by Methanol Extract from the Calyx of Hibiscus Sabdariffa Linn

Central Asian Journal of Medical Sciences, 2018
Objectives: This study focused on the antioxidant and anticancer activities of methanolic extract of Hibiscus sabdariffa calyx. Methods: In vitro methods were used to determine the different types of phytochemical content and antioxidant activity of ...
Tanzima Yeasmin, Hanif Ali, Rumana Yesmin, Majidul Islam, Akter Hoshen, Rowshanul Habib, Mohammed Abdus Satter, Kazi Muhammad Faisal Haque   +7 more
doaj   +1 more source

Anticancer redox activity of gallium nanoparticles accompanied with low dose of gamma radiation in female mice

Tumor Biology, 2018
Guided treatments with nanoparticles and radiotherapy are a new approach in cancer therapy. This study evaluated the beneficial antitumor effects of γ-radiation together with gallium nanoparticles against solid Ehrlich carcinoma in female mice.
Eman I Kandil, Sawsan M El-sonbaty, Fatma SM Moawed, Ola MS Khedr   +3 more
doaj   +1 more source

Prophylactic antineoplastic activity of Toxoplasma gondii RH derived antigen against ehrlich solid carcinoma with evidence of shared antigens by comparative immunoblotting

Infectious Agents and Cancer, 2023
Background With cancer cases escalation, an urgent request to develop novel combating strategies arise. Pathogen-based cancer-immunotherapy is getting more consideration.
Maha M. Eissa, Maha R. Gaafar, Layla K. Younis, Cherine A. Ismail, Nahla El Skhawy   +4 more
doaj   +1 more source

Quercetin activates vitamin D receptor and ameliorates breast cancer induced hepatic inflammation and fibrosis

Frontiers in Nutrition, 2023
AimsTo explore the hepatoprotective role of quercetin and its novel molecular mechanism of action on breast cancer associated hepatic inflammation and fibrosis via Vitamin D receptor (VDR).Main methodsWe used Ehrlich Ascites Carcinoma (mouse mammary ...
Nirmala G. Sannappa Gowda, Varsha D. Shiragannavar, Lakshana D. Puttahanumantharayappa, Ashwini Tumkur Shivakumar, Siva Dallavalasa, Chaithanya G. Basavaraju, Smitha S. Bhat, Shashanka K. Prasad, Shashanka K. Prasad, Ravishankar M. Vamadevaiah, SubbaRao V. Madhunapantula, Prasanna K. Santhekadur   +11 more
doaj   +1 more source

Immunization Against Ehrlich's Ascites Carcinoma with X-Irradiated Tumor Cells.

Experimental Biology and Medicine, 1959
SummaryPre-immunization with irradiated Ehrlich's ascites tumor cells protected mice against subsequent ip transplants of viable cells. Immunization procedures started one day after sc challenge with the tumor, significantly reduced mortality. Such post-immunization did not inhibit the rapid multiplication that follows ip transplantation of the tumor ...
D M, DONALDSON, J R, MITCHELL
openaire   +2 more sources

Antitumor and radiosensitizing synergistic effects of apigenin and cryptotanshinone against solid Ehrlich carcinoma in female mice

Tumor Biology, 2017
Considerable attention has been paid to the introduction of novel naturally occurring plant-derived radiosensitizer compounds in order to augment the radiation efficacy and improve the treatment outcome of different tumors.
Amina M Medhat, Khaled Sh Azab, Mahmoud M Said, Neama M El Fatih, Nermeen M El Bakary   +4 more
doaj   +1 more source

Fermented milk supplemented with water-soluble curcumin ameliorates survival rate, selected biochemical parameters and fecal microbiota of Ehrlich ascites carcinoma-bearing mice

SN Applied Sciences, 2023
This study assessed the impact of fermented cow and soy milk supplemented with curcumin on enhancement the health status of female Swiss mice under Ehrlich ascites carcinoma (EAC) condition.
Tay E. Abdelrazik, Abeer M. Badr, Fouad M. F. Elshaghabee   +2 more
doaj   +1 more source