Results 31 to 40 of about 8,031 (177)

Evaluation of the level of gamma radiation dose on some immune system parameters against cancer

Bioscience Journal, 2019
The positive impact of exposure to low-dose gamma irradiation (LDR) on tumor regression and immune response has recently been emphasized. The present study aimed to investigate the T-helper 1 / T-helper 2 (Th1/ Th2) cytokine balance, serum protein ...
Abdelmonsef Abdelaziz Elhadary, Ebtisam Abdelmageed Marzook, Hanan Abdallah Abdelmonem   +2 more
doaj   +3 more sources

Synthesis and Antitumor Activity of Doxycycline Polymeric Nanoparticles: Effect on Tumor Apoptosis in Solid Ehrlich Carcinoma [PDF]

Molecules, 2020
Objectives: The aim of this study was to prepare doxycycline polymeric nanoparticles (DOXY-PNPs) with hope to enhance its chemotherapeutic potential against solid Ehrlich carcinoma (SEC). Methods: Three DOXY-PNPs were formulated by nanoprecipitation method using hydroxypropyl methyl cellulose (HPMC) as a polymer.
Ahmed R. Gardouh, Mohammed A. Attia, Eman T. Enan, Alaaeldeen M. Elbahaie, Rania A. Fouad, Mohamed El-Shafey, Amal M. Youssef, Suliman Y. Alomar, Zinab Abd-Elhady Ali, Sawsan A. Zaitone, Mona K.E. Qushawy   +10 more
openaire   +3 more sources

Antitumor activity of two Streptomyces extracts (Ag18 & Ag20) on Ehrlich ascites tumor in mice in vitro and in vivo studies [PDF]

Journal of Bioscience and Applied Research, 2015
This study aimed to evaluate the potent antitumor activity of metabolites from Streptomyces as antitumor activity using in vitro and in vivo studies. The Streptomyces were purely isolated from the soil samples, processed to obtain their extracts.
Amany Gaber, Osama Badr, Saad Emara, Atef Ibrahim   +3 more
doaj   +1 more source

MOESM1 of Tumor growth activity of duloxetine in Ehrlich carcinoma in mice

, 2018
Additional file 1. Additional tables.
Moura, Ed, Cunha Leal, Plinio, Serra, Izabel, Paulo Ribeiro, Bruno, Nascimento, Johnny, Nascimento, Flavia, Sakata, Rioko   +6 more
openaire   +1 more source

A nanoplatform that induces dual‐amino acid deprivation to reverse tumor immunosuppression and enhance metabolic immunotherapy

BMEMat, EarlyView.
ZIF‐8‐based nanoparticles co‐delivering CB‐839 (glutaminase inhibitor) and 1‐MT (IDO1 inhibitor), dual‐targeting glutamine/tryptophan metabolism to induce immunogenic cell death, activate STING, block kynurenine production, reverse immunosuppression, and enhance cancer immunotherapy to suppress primary/distant tumors.
Wenli Ning, Yunhan Sun, Mingyang Li, Shilu Liu, Fangjie Yi, Hongfei Wang, Ruibing Bai, Dongdong Liu, Fen Zhao, Guiqiang Zhang, Xiao Fu   +10 more
wiley   +1 more source

Synthesis, Cytotoxicity, and Apoptosis‐Associated Cell Death Activity of an Isatin‐Containing Pyrimidine‐Derived Cu(II) Complex

Journal of Applied Toxicology, EarlyView.
ABSTRACT A Cu(II) complex derived from a pyrimidine with the isatin group was synthesized and tested for its cytotoxic effects on A549 lung cancer and MCF‐7 breast cancer cell lines, as well as its effects on apoptosis‐associated cell death and cell cycle regulation in A549 cells. To evaluate cytotoxicity, MTT assays were performed at 24, 48, and 72 h,
Müjgan Kesik Oktay, Cansu Topkaya, Elif Kağa, Yasin Eren, Ramazan Güp   +4 more
wiley   +1 more source

Muscle wasting in cancer cachexia: Mechanisms and the role of exercise

Experimental Physiology, EarlyView.
Abstract Cancer cachexia (CC) is a multifactorial disease marked by a severe and progressive loss of lean muscle mass and characterized further by inflammation and a negative energy/protein balance, ultimately leading to muscle atrophy and loss of muscle tissue.
Zoe P. Libramento, Louisa Tichy, Traci L. Parry   +2 more
wiley   +1 more source

Metabolic effects of Lactuca sativa extract on experimentally induced Ehrlich ascites carcinoma [PDF]

Benha Veterinary Medical Journal, 2018
The present study aimed to determine the effect of Lactuca sativa (lettuce) extract on alleviating Ehrlich ascites carcinoma (EAC) in female mice. EAC was induced by injection of 0.2 ml of (2.5×106 tumor cells with single cells suspension) in the medial ...
Nancy M. H. Salaam, Ahmed I. E. Awadin, Omnia M. Abd-elhamid, M. K Mahfouz, H. A Abdelmaksoud   +4 more
doaj   +1 more source

Traditional Uses, Phytochemistry, and Multi‐Target Pharmacological Activities of Senna alexandrina

Chemistry &Biodiversity, Volume 23, Issue 10, October 2026.
Senna alexandrina is a medicinally important plant with documented use across Traditional Chinese, Islamic, Ayurvedic, and Unani medicine systems. Phytochemical investigations have yielded 219 characterized compounds, predominantly anthraquinones, flavonoids, and polysaccharides, distributed across leaves, pods, and aerial parts.
Diana Afrina Rella, Khai‐Lin Hew, Yeun‐Mun Choo   +2 more
wiley   +1 more source

Antibacterial and antitumor activities of a lectin-rich preparation from Microgramma vacciniifolia rhizome

Current Research in Pharmacology and Drug Discovery, 2022
The rhizome of Microgramma vacciniifolia contains a lectin (carbohydrate-binding protein) called MvRL. Studies demonstrated that a MvRL-rich fraction did not show in vivo genotoxicity and acute toxicity in mice. This study aimed to evaluate the MvRL-rich
Gabriela Cavalcante da Silva, Alisson Macário de Oliveira, Wêndeo Kennedy Costa, Antônio Felix da Silva Filho, Maira Galdino da Rocha Pitta, Moacyr Jesus Barreto de Melo Rêgo, Ivone Antônia de Souza, Patrícia Maria Guedes Paiva, Thiago Henrique Napoleão   +8 more
doaj   +1 more source