Results 41 to 50 of about 21,761 (224)

Overview of Genus Prosopis Toxicity Reports and its Beneficial Biomedical Properties [PDF]

, 2016
Secondary plant metabolites are regarded as promising sources of plant-protecting substances and they are one of the most important lines of plant defense against pests. The range of cellular targets for these substances is very wide and covers metabolic
Gamarra Luques, Carlos Diego, Hapon, María Belén, Persia, Andres, Rinaldini, Estefanía   +3 more
core   +1 more source

Antitumor activity of two Streptomyces extracts (Ag18 & Ag20) on Ehrlich ascites tumor in mice in vitro and in vivo studies [PDF]

Journal of Bioscience and Applied Research, 2015
This study aimed to evaluate the potent antitumor activity of metabolites from Streptomyces as antitumor activity using in vitro and in vivo studies. The Streptomyces were purely isolated from the soil samples, processed to obtain their extracts.
Amany Gaber, Osama Badr, Saad Emara, Atef Ibrahim   +3 more
doaj   +1 more source

Studies on the host-mediated action of the streptococcal preparation, OK-432, in cancer chemotherapy [PDF]

, 1974
The streptococcal preparation, OK.432, with predominant host-mediated mode of action, was studied. By giving OK-432 to mice intraperitoneally prior to transplantation of Ehrlich carcinoma, a host-mediated action to increase life-span was clearly ...
Hiraki, Kiyoshi, Kimura, Ikuro, Onoshi, Taisuke, Sugiyama, Motoharu, Watanabe, Tatsuo, Yasuhara, Shozo   +5 more
core   +1 more source

Antitumor Activity of Prosopis glandulosa Torr. on Ehrlich Ascites Carcinoma (EAC) Tumor Bearing Mice.

Iranian journal of pharmaceutical research : IJPR, 2011
The antitumor activity of ethanol extract of Prosopis glandulosa Torr. (EPG) was evaluated against Ehrlich ascites carcinoma (EAC) tumor model in Swiss albino mice on dose dependent manner. The activity was assessed using survival time, average increase in body weight, hematological parameters and solid tumor volume.
Senthil Kumar, Raju, Rajkapoor, Balasubramanian, Perumal, Perumal, Dhanasekaran, Thangavel, Alvin Jose, Manonmani, Jothimanivannan, Chennakesavalu   +5 more
openaire   +2 more sources

European surveillance of infections in cancer patients - ESIC [PDF]

, 1999
Major advances in cancer therapy result from development of multidrug chemotherapy regimens. Besides death from tumor progression, infections are currently one of the major causes of mortality and morbidity.
Buchheidt, D., Donnelly, J. P., Helmerking, M., Hiddemann, Wolfgang, Karthaus, M., Krcmery, V., Schiel, X., Wilhelm, M.   +7 more
core   +1 more source

A nanoplatform that induces dual‐amino acid deprivation to reverse tumor immunosuppression and enhance metabolic immunotherapy

BMEMat, EarlyView.
ZIF‐8‐based nanoparticles co‐delivering CB‐839 (glutaminase inhibitor) and 1‐MT (IDO1 inhibitor), dual‐targeting glutamine/tryptophan metabolism to induce immunogenic cell death, activate STING, block kynurenine production, reverse immunosuppression, and enhance cancer immunotherapy to suppress primary/distant tumors.
Wenli Ning, Yunhan Sun, Mingyang Li, Shilu Liu, Fangjie Yi, Hongfei Wang, Ruibing Bai, Dongdong Liu, Fen Zhao, Guiqiang Zhang, Xiao Fu   +10 more
wiley   +1 more source

Induction of IL‐9‐producing CD8+ T cells by ascochlorin derivatives

British Journal of Pharmacology, EarlyView.
A newly synthesised ascochlorin derivative, N184, induces small amounts of IL‐9‐producing CD8+ T cells. N184 improved the survival of CD8+ T cells and enhanced their antitumour activity, partially in an IL‐9‐dependent manner. The antitumour effect was completely dependent on IFNγ secretion rather than the cytotoxic activity of CD8+ T cells.
Natsumi Imano, Mikako Nishida, Miho Tokumasu, Weiyang Zhao, Nahoko Yamashita, Heiichiro Udono   +5 more
wiley   +1 more source

Anti-neoplastic action of Cimetidine/Vitamin C on histamine and the PI3K/AKT/mTOR pathway in Ehrlich breast cancer

Scientific Reports, 2022
The main focus of our study is to assess the anti-cancer activity of cimetidine and vitamin C via combating the tumor supportive role of mast cell mediators (histamine, VEGF, and TNF-α) within the tumor microenvironment and their effect on the protein ...
Sherihan Salaheldin Abdelhamid Ibrahim, Sarah A. Abd El-Aal, Ahmed M. Reda, Samar El Achy, Yasmine Shahine   +4 more
doaj   +1 more source

Antibacterial and antitumor activities of a lectin-rich preparation from Microgramma vacciniifolia rhizome

Current Research in Pharmacology and Drug Discovery, 2022
The rhizome of Microgramma vacciniifolia contains a lectin (carbohydrate-binding protein) called MvRL. Studies demonstrated that a MvRL-rich fraction did not show in vivo genotoxicity and acute toxicity in mice. This study aimed to evaluate the MvRL-rich
Gabriela Cavalcante da Silva, Alisson Macário de Oliveira, Wêndeo Kennedy Costa, Antônio Felix da Silva Filho, Maira Galdino da Rocha Pitta, Moacyr Jesus Barreto de Melo Rêgo, Ivone Antônia de Souza, Patrícia Maria Guedes Paiva, Thiago Henrique Napoleão   +8 more
doaj   +1 more source

Studies on relationship between serum properdin and cancer II. Studies on the serum properdin levels of tumor bearing animals and patients with malignant tumors [PDF]

, 1961
1. The properdin levels in sera from mice bearing Ehrlich ascitic carcinoma and from rabbits with Brown-Pearce carcinoma decrease inversely with the increase of the ascites or the tumors. In the incipient period of tumor transplantation, the level rather
Orita, Kunzo
core   +1 more source