Results 131 to 140 of about 1,923,290 (310)
This review summarizes recent advances in metal‐based nanomaterials (MBNs) as multifunctional platforms for next‐generation diagnostics and nanodynamic therapies (NDTs), highlighting their structural tunability, diverse therapeutic modalities, and broad biomedical applications in oncology and infectious disease control.
Qihang Ding +11 more
wiley +1 more source
There is great geographical variation in the distribution of hepatocellular carcinoma (HCC), with the majority of all cases worldwide found in the Asia–Pacific region, where HCC is one of the leading public health problems.
M. Omata +20 more
semanticscholar +1 more source
Mitochondria‐Targeted Nanomotor: H2S‐Driven Cascade Therapy for Hepatocellular Carcinoma
A mitochondrial‐targeted nanomotor integrates photodynamic therapy, mild photothermal therapy, and enzyme dynamic therapy into a self‐amplifying cascade through H2S‐driven metabolic reprogramming. Abstract Despite advances in combination therapies for cancer treatment, most strategies rely on modular‐additive designs that lack dynamic molecular cues to
Chengcheng Li +11 more
wiley +1 more source
OBJECTIVES: Fibrolamellar hepatocellular carcinoma is a rare primary malignant liver tumor that differs from conventional hepatocellular carcinoma in several aspects.
Aline Lopes Chagas +10 more
doaj +1 more source
This study introduces glutathione‐stabilized gold nanoparticles for targeted lithium delivery (LiG‐AuNPs), enabling the controlled modulation of Glycogen Synthase Kinase‐3 (GSK‐3β). These non‐toxic, 2‐nm particles release lithium intracellularly, effectively inhibiting GSK‐3β in the brain without significant plasma lithium alterations.
Antonio Buonerba +20 more
wiley +1 more source
Advances in Electrochemical Urea Biosensors: Trends and Future Prospects
This review explores advances in enzymatic and non‐enzymatic biosensors, emphasizing electrochemical detection, material innovations, and IoT integration for real‐time tracking. Key challenges and future opportunities in enhancing sensitivity, selectivity, and portability are highlighted, showcasing biosensors as promising tools for next‐generation ...
Samar Shurbaji +6 more
wiley +1 more source
Role of transarterial chemoembolization as neoadjuvant treatment in T2 stage patients waiting for liver transplantation [PDF]
RIASSUNTO Scopo: Valutare retrospettivamente i risultati clinici a lungo termine di pazienti cirrotici con HCC allo stadio T2 sottoposti a trapianto ortotopico di fegato (TOF) dopo chemioembolizzazione intraarteriosa (TACE), rispetto ai risultati ...
BARATTINI, MATTEO
core
ATF5‐Dependent GDF15 Expression Mediates Anesthesia‐Induced Neuroprotection Against Stroke
Anesthesia‐induced preconditioning protects against perioperative stroke. By manipulating ATF5 in excitatory neurons, it is shown that anesthesia‐driven ATF5 upregulation activates the mitochondrial unfolded protein response (UPRmt) and elevates GDF15 expression.
Xianshu Ju +11 more
wiley +1 more source
The study identifies TRIM15 as a key driver in the development of obesity‐associated esophageal adenocarcinoma (EAC). Mechanistically, TRIM15 degrades YY2 through the proteasome pathway, suppressing FOXRED1 transcription and ultimately accelerating tumor proliferation.
Haohui Wang +10 more
wiley +1 more source
Evaluation of Hepatocellular Carcinoma Transarterial Chemoembolization using Quantitative Analysis of 2D and 3D Real-time Contrast Enhanced Ultrasound. [PDF]
Quantitative 2D and 3D contrast-enhanced ultrasound (CEUS) was assessed to evaluate early transarterial chemoembolization (TACE) treatment response. Seventeen patients scheduled for TACE for the treatment of hepatocellular carcinoma participated in the ...
Eisenbrey, John R. +7 more
core +1 more source

