Results 161 to 170 of about 942,442 (285)

Retraction: T-box Transcription Factor Tbx3 Contributes to Human Hepatocellular Carcinoma Cell Migration and Invasion by Repressing E-Cadherin Expression. [PDF]

Oncol Res
Oncology Research Editorial Office.
europepmc   +1 more source

Autophagy Orchestrates Anti‐Tumor Immunity to Enhance Chemosensitivity via the FBXW2/C/EBPβ/TIMP‐2 Axis in Colorectal Cancer

Advanced Science, EarlyView.
Chemotherapy leverages tumor‐cell autophagy to reshape the colorectal cancer immune microenvironment. Autophagy degrades FBXW2 to promote C/EBPβ‐mediated TIMP‐2 transcription and MMP‐9 suppression, driving intra‐tumoral CD8+ T‐cell infiltration. Targeting MMP‐2/9 or restoring TIMP‐2 overcomes chemo‐resistance in autophagy‐deficient tumors. ABSTRACT The
Bing Cheng, Chaoying Wei, Zhitong Niu, Jinxin Chen, Guojie Long, Yingzhen Weng, Qiufeng Liu, Yue Jiang, Panpan Wang, Ronghua Zhang, Qiang Yu, Xiaojian Wu, Wenyu Wang   +12 more
wiley   +1 more source

RETRACTION: Long Noncoding RNA NR2F1-AS1 Enhances the Migration and Invasion of Hepatocellular Carcinoma via Modulating miR-642a/DEK Pathway. [PDF]

J Oncol
Oncology JO.
europepmc   +1 more source

An Optimized Freeze‐Dry Multimodal Workflow for Sequential Micro‐CT Imaging, Histology, and Molecular Profiling: A Use Case in Human Liver Fibrosis

Advanced Science, EarlyView.
Optimized freeze‐drying and eosin staining deliver artifact‐free micro‐CT images of liver tissue at near‐histological detail, then hand the same specimen back for sectioning, staining, and sequencing. Fibrotic volume distinguishes normal liver from cirrhosis, while preserved RNA reveals inflammatory gene upregulation—one biopsy, three dimensions, and a
Kristijan Skok, Laura Činč Ćurić, Jernej Vajda, Silvia Schauer, Martin Wagner, Rudolf Stauber, Carolin Lackner, Karl Kashofer, Markus Plass, Giovanny Rodriguez Blanco, Ian R. Wanless, Uroš Maver, Katrin Panzitt, Boštjan Vihar   +13 more
wiley   +1 more source

Combined hepatocellular cholangiocarcinoma: A rare hepatic malignancy exhibiting concurrent imaging features of hepatocellular carcinoma and intrahepatic cholangiocarcinoma. [PDF]

Radiol Case Rep
Qian XJ, Girgis S, Wilson MP, Low G.
europepmc   +1 more source

The Cancer Cell Metabolic Reprogramming Remodels the Tumor Microenvironment: Molecular Mechanisms and Therapeutic Strategies

Advanced Science, EarlyView.
This review elucidates how cancer cell metabolic reprogramming—across glucose, lipid, amino acid, and nucleotide pathways—remodels the tumor microenvironment to suppress anti‐tumor immunity and promote immune escape. Targeting these metabolic axes offers promising strategies to overcome immunotherapy resistance and enhance cancer treatment.
Guoqing Xiang, Zhicheng Zhou, Xue Jiang, Zhenguang Du, Yangyang Zhan, Xinli Liu   +5 more
wiley   +1 more source

DEB-TACE Combined with Immunotherapy and Targeted Therapy for Advanced Hepatocellular Carcinoma with Scapular Metastasis: A Case Report. [PDF]

J Hepatocell Carcinoma
Zhang W, Kang D, Xu Q, Piao L.
europepmc   +1 more source

GPC-3 in hepatocellular carcinoma: current perspectives

, 2016
Yongle Wu,1 Hui Liu,2 Huiguo Ding1 1Department of Gastroenterology and Hepatology, 2Department of Pathology, Beijing You’an Hospital, Affiliated with Capital Medical University, Beijing, People’s Republic of China Abstract: Glypican-3 (GPC3),
Liu H, Ding H, Wu Y
core  

OAF Blocks SIAH1‐Mediated Degradation of SCPX, a Therapeutic Strategy for MASLD

Advanced Science, EarlyView.
This study shows OAF directly binds to SCPX and inhibits its interaction with the E3 ligase SIAH1, thereby protecting SCPX from ubiquitin‐dependent degradation and stabilizing its levels. This OAF‐SCPX axis represents a novel pathway in lipid homeostasis, highlighting OAF as a promising therapeutic candidate for MASLD.
Zongxi Li, Jingyue Song, Kaili Ma, Shunan Tang, Shuqian Wang, Wenya Ji, Chen Lu, Ting Zhang, Huaping Zheng, Xiaowei Zheng, Shanshan Lai, Cheng Deng   +11 more
wiley   +1 more source

Serum AKR1B10 in Early Hepatocellular Carcinoma: Superiority to AFP or Disease-Spectrum-Dependent Complementarity? [PDF]

Liver Int
Tian Y, Li W.
europepmc   +1 more source