Results 231 to 240 of about 1,772,404 (331)

C1q+ Macrophage–Tumor Cell Interaction Promoted Tumorigenesis via GPR17/PI3K/AKT Pathway Induced DNA Hypermethylation in Nasopharyngeal Carcinoma

open access: yesAdvanced Science, EarlyView.
In the TME of NPC, C1q secreted by C1q+ TAMs interacted with GPR17 to activate PI3K/AKT signaling through strengthening GPR17 coupling PI3K and increasing calcium levels in tumor cells. The activated PI3K/AKT signaling further induces DNA hypermethylation to promote the malignancy and stemness of tumor cells.
Yunzhi Liu   +11 more
wiley   +1 more source

The diagnosis, classification, and treatment of sarcoma in this era of artificial intelligence and immunotherapy

open access: yesCancer Communications, Volume 42, Issue 12, Page 1288-1313, December 2022., 2022
Abstract Soft‐tissue sarcomas (STS) represent a group of rare and heterogeneous tumors associated with several challenges, including incorrect or late diagnosis, the lack of clinical expertise, and limited therapeutic options. Digital pathology and radiomics represent transformative technologies that appear promising for improving the accuracy of ...
Amandine Crombé   +2 more
wiley   +1 more source

Chronological changes in etiology, pathological and imaging findings in primary liver cancer from 2001 to 2020. [PDF]

open access: yesJpn J Clin Oncol
Tsuzaki J   +15 more
europepmc   +1 more source

Association between surgical difficulty and tumor location based on subsegments of the Glisson branches in laparoscopic liver resection

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
Our study validates the need for a more detailed and accurate tumor location scoring system within the IWATE criteria. The proposed classification based on subsegmental Glisson branches provides a sophisticated tool for assessing LLR difficulty. By providing a more detailed assessment, this new system has the potential to enhance surgical planning ...
Taisuke Imamura   +9 more
wiley   +1 more source

Updated risk prediction model for pancreaticoduodenectomy using data from the National Clinical Database in Japan

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
The calibration plots of the updated risk models for the endpoints were analyzed in each cohort. The predicted probability of each endpoint matched the observed probability in the development and validation cohorts. Abstract Aim Risk prediction models for mortality, severe postoperative complications, and postoperative pancreatic fistula in patients ...
Masamichi Mizuma   +8 more
wiley   +1 more source

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