In the TME of NPC, C1q secreted by C1q+ TAMs interacted with GPR17 to activate PI3K/AKT signaling through strengthening GPR17 coupling PI3K and increasing calcium levels in tumor cells. The activated PI3K/AKT signaling further induces DNA hypermethylation to promote the malignancy and stemness of tumor cells.
Yunzhi Liu+11 more
wiley +1 more source
Abstract Soft‐tissue sarcomas (STS) represent a group of rare and heterogeneous tumors associated with several challenges, including incorrect or late diagnosis, the lack of clinical expertise, and limited therapeutic options. Digital pathology and radiomics represent transformative technologies that appear promising for improving the accuracy of ...
Amandine Crombé+2 more
wiley +1 more source
A Chemotherapy Response-Related Gene Signature and DNAJC8 as Key Mediators of Hepatocellular Carcinoma Progression and Drug Resistance. [PDF]
Ye Y, Zeng Y, Huang S, Zhu C, Wang Q.
europepmc +1 more source
Chronological changes in etiology, pathological and imaging findings in primary liver cancer from 2001 to 2020. [PDF]
Tsuzaki J+15 more
europepmc +1 more source
Insights into the history and trends of nanotechnology for the treatment of hepatocellular carcinoma: a bibliometric-based visual analysis. [PDF]
Zhao Y, Wang X, Yang X, Li J, Han B.
europepmc +1 more source
Research Progress on the Protective Effect of Green Tea Polyphenol (-)-Epigallocatechin-3-Gallate (EGCG) on the Liver. [PDF]
Zhou F, Deng S, Luo Y, Liu Z, Liu C.
europepmc +1 more source
Our study validates the need for a more detailed and accurate tumor location scoring system within the IWATE criteria. The proposed classification based on subsegmental Glisson branches provides a sophisticated tool for assessing LLR difficulty. By providing a more detailed assessment, this new system has the potential to enhance surgical planning ...
Taisuke Imamura+9 more
wiley +1 more source
Two treatment methods for hepatocellular carcinoma: Lenvatinib or bevacizumab combined with sintilimab and interventional therapy. [PDF]
Zhao FY, Zhang XM, Qian NS.
europepmc +1 more source
The calibration plots of the updated risk models for the endpoints were analyzed in each cohort. The predicted probability of each endpoint matched the observed probability in the development and validation cohorts. Abstract Aim Risk prediction models for mortality, severe postoperative complications, and postoperative pancreatic fistula in patients ...
Masamichi Mizuma+8 more
wiley +1 more source
A novel approach for engineering DHCM/GelMA microgels: application in hepatocellular carcinoma cell encapsulation and chemoresistance research. [PDF]
Zhou D+7 more
europepmc +1 more source