Results 261 to 270 of about 1,937,940 (311)

Erratum: LncRNA <i>HEIH</i> modulates the proliferation, migration, and invasion of hepatocellular carcinoma cells by regulating the <i>miR-193a-5p</i>/<i>CDK8</i> axis. [PDF]

Transl Cancer Res
Editorial Office.
europepmc   +1 more source

Hepatectomy in children. [PDF]

, 1982
Iwatsuki, S, Starzl, TE
core  

T Cell Exhaustion in Cancer Immunotherapy: Heterogeneity, Mechanisms, and Therapeutic Opportunities

Advanced Science, EarlyView.
T cell exhaustion limits immunotherapy efficacy. This article delineates its progression from stem‐like to terminally exhausted states, governed by persistent antigen, transcription factors, epigenetics, and metabolism. It maps the exhaustion landscape in the TME and proposes integrated reversal strategies, providing a translational roadmap to overcome
Yang Yu, Xiaoyu Yao, Qingyang Wang, Mengrui Yang, Runze Li, Jiangjiang Qin, Jing Zhuang, Changgang Sun   +7 more
wiley   +1 more source

Primary and secondary pseudo-stability and progression after atezolizumab with and without bevacizumab. [PDF]

J Immunother Cancer
Govindu S, Gowda P, Muquith M, Espinoza M, Hsiehchen D.   +4 more
europepmc   +1 more source

Targeted Degradation of eEF2K by a Structure‐Guided PROTAC Strategy for the Treatment of Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
This study developed an eEF2K‐targeting PROTAC, A6, that efficiently degrades eEF2K in TNBC cells, inhibiting tumor growth in vitro and in vivo. To enhance tumor‐specific delivery, we engineered A6@ZIF‐8, a pH‐sensitive nanocarrier, which improved drug accumulation at tumor sites, offering a promising therapeutic strategy for TNBC through targeted ...
Shijun Cao, Changxin Zhong, Shilong Jiang, Yungui Li, Yang Xi, Mingxuan Xiao, Ting Jiang, Xiaoya Wan, Zonglin Chen, Xiaohui Yu, Yan Cheng   +10 more
wiley   +1 more source

Prognostic Determinants and Treatment Strategies Associated with Long-Term Survival in Early-Stage Hepatocellular Carcinoma: A Retrospective Cohort Study. [PDF]

J Hepatocell Carcinoma
Pan KC, Huang HL, Lu SN, Chang TS.
europepmc   +1 more source

Dual Aptamers‐Based SETDB1 PROTACs as Effective Anti‐Tumor Strategies for Breast Cancer

Advanced Science, EarlyView.
This study establishes dual‐aptamer PROTACs targeting SETDB1 using a SETDB1‐specific aptamer conjugated to AS1411. The designed PROTACs penetrate cells, recruit MDM2 to degrade SETDB1, and inhibit cancer cell proliferation and migration. Remarkably, they also overcome tamoxifen resistance and enhance CD8+ T cell cytotoxicity, suppressing tumor growth ...
Yanxuan Guo, Yingge Lv, Shuyu Huang, Chang Liu, Yan Ouyang, Bei Lan, Chenghao Xuan   +6 more
wiley   +1 more source

Microwave ablation for hepatocellular carcinoma: A single-center experience and outcomes. [PDF]

North Clin Istanb
Demir M, Avci MT, Agackiran A, Emir S, Acar A, Canbak T.   +5 more
europepmc   +1 more source

Erratum for the Research Article "Fasting improves therapeutic response in hepatocellular carcinoma through p53-dependent metabolic synergism" by J. Krstic <i>et al</i>.

Sci Adv
europepmc   +1 more source

Ultrasound imaging in orthotopic hepatocellular carcinoma models: Promise, practicality, and points for refinement. [PDF]

World J Hepatol
Ghosh D, Kumar A.
europepmc   +1 more source