Results 261 to 270 of about 2,051,186 (321)

A comprehensive proteome and phosphoproteome atlas across nine organs of the Chinese hamster

Animal Models and Experimental Medicine, EarlyView.
This study presents the first comprehensive proteome and phosphoproteome atlas of the Chinese hamster across nine organs (heart, liver, lung, kidney, spleen, cerebral cortex, skeletal muscle, stomach, and testis or ovary). A total of 14 219 proteins were identified in the proteome, with 11 828 phosphorylated proteins and 47 122 phosphorylation sites ...
Luyao Zhang, Tao Ding, Wanjun Peng, Jie Kong, Xiaoyue Tang, Jiyu Xu, Qiaochu Wang, Zhiyi Zhang, Chunmei Shi, Yizhuo Tian, Huilan Yang, Yehong Yang, Yue Wu, Xiaoyan Liu, Jiangfeng Liu, Juntao Yang   +15 more
wiley   +1 more source

Incorporation of Novel Synthetic Glycolipids in Liposomal Nanoparticles Affects Opsonization and In Vivo Clearance

Angewandte Chemie, EarlyView.
We prepared five glycosylated liposomal nanoparticles (G‐LNPs) to investigate the role of glycosylation and protein corona in modulating the in vivo behavior of G‐LNPs. We show that IgG and complement C3 adsorption enhanced liposomal nanoparticle clearance, with IgG promoting subsequent C3 binding.
Yingjie Yu, Xuehan Li, Yu Gao, Shijia Tao, Xiaofei Li, Lemei Zhao, Wenshuai Han, Hao Fan, Ying Qiu, Man Wang, Luying Zhou, Xiaoyan Fang, Wenhua Yang, Haiyang Zhang, Volker Mailänder, Daniel Crespy, Katharina Landfester, Shuai Jiang, Xiangzhao Mao   +18 more
wiley   +2 more sources

Transcriptomic validation of a 7,12 Dimethylbenz(a)anthracene (DMBA)‐induced leukemia rat model: Parallels with human leukemogenesis

Animal Models and Experimental Medicine, EarlyView.
7,12‐Dimethylbenz[a]anthracene (DMBA) could induce leukemia and other types of cancers in rat models. Transcriptomics revealed gene expression profile that parallels with human leukemia. DMBA‐induced differential gene expression could validate the developed rat model.
Khaldoon Alsamman, Omar S. El‐Masry
wiley   +1 more source

Vemurafenib Induces Apoptosis via JNK Activation and AKT Inhibition in Hepatocellular Carcinoma. [PDF]

J Cancer
Cho YR, Huang K, Liu Z, Kim H, Kim CY, Ma L, Yee N, Kim CR, Park GH, Zhang J, Ryoo ZY, Kim SH, Kim MO.   +12 more
europepmc   +1 more source

Therapeutic Applications of Stimuli‐Based Release and Engineering of Extracellular Vesicles

Advanced NanoBiomed Research, EarlyView.
This review summarizes the effects of endogenous and exogenous stimuli, their effects on the natural release of extracellular vesicles, as well as their uptake and release. It also gives an overview of stimuli‐responsive EVs and their therapeutic applications. Extracellular vesicles (EVs), nano‐ to microsized lipid bilayer membrane‐bound particles, are
Gloria Kemunto, Kristen Dellinger
wiley   +1 more source

Identification of <i>EFNA</i> family as new potential prognostic biomarkers correlated with immune cell infiltration in hepatocellular carcinoma. [PDF]

Transl Cancer Res
Wang J, Li X, Zheng B, Chen Z, Chen F, Fang X.   +5 more
europepmc   +1 more source

Development and validation of a digital PCR assay targeting plasma <i>FAR1</i> methylation for early detection of hepatocellular carcinoma. [PDF]

Epigenetics
Park SJ, Lee YY, Chung YK, Jung BH, An J, Han J, Moon Y, Wang HJ.   +7 more
europepmc   +1 more source

"WBC-HBP Dissociation" Unveils Occult Xanthogranulomatous Inflammation Mimicking Hepatocellular Carcinoma in Diabetic Patients. [PDF]

J Hepatocell Carcinoma
Zhu XY, Liu KC, Zhu ZB, Zhang SG.
europepmc   +1 more source

Nanoclay‐Engineered Scaffolds for the Controlled Delivery of Biomolecules in Regenerative Medicine

Asia-Pacific Journal of Chemical Engineering, EarlyView.
ABSTRACT Regenerative medicine combines biomaterials, cells, scaffolds, and bioactive agents via modern technologies to aid in the reconstruction and repair of damaged tissues. Among these, nanoclay scaffolds have demonstrated unique advantages in facilitating the delivery of therapeutic agents.
Mehri Shadi, Saeed Vafaei‐Nezhad, Ahmad Gholamalizadeh Ahangar   +2 more
wiley   +1 more source

Transcriptomic Analysis Reveals the Role of <i>TRIM26</i> in Hepatocellular Carcinoma and Its Association With the Wnt/<i>β</i>-catenin Signaling Pathway. [PDF]

Hum Mutat
Song C, Hou Z, Wu H, Li X.
europepmc   +1 more source