Results 291 to 300 of about 2,051,186 (321)
Some of the next articles are maybe not open access.

Global epidemiology and genetics of hepatocellular carcinoma.

Gastroenterology, 2023
Hepatocellular carcinoma (HCC) is one of the leading cancers worldwide. Classically, HCC develops in genetically susceptible individuals who are exposed to risk factors especially in the presence of liver cirrhosis.
M. Toh   +6 more
semanticscholar   +1 more source

Nivolumab versus sorafenib in advanced hepatocellular carcinoma (CheckMate 459): a randomised, multicentre, open-label, phase 3 trial.

The Lancet Oncology, 2021
BACKGROUND Single-agent nivolumab showed durable responses, manageable safety, and promising survival in patients with advanced hepatocellular carcinoma in the phase 1-2 CheckMate 040 study.
T. Yau   +26 more
semanticscholar   +1 more source

Sintilimab plus a bevacizumab biosimilar (IBI305) versus sorafenib in unresectable hepatocellular carcinoma (ORIENT-32): a randomised, open-label, phase 2-3 study.

The Lancet Oncology, 2021
BACKGROUND China has a high burden of hepatocellular carcinoma, and hepatitis B virus (HBV) infection is the main causative factor. Patients with hepatocellular carcinoma have a poor prognosis and a substantial unmet clinical need.
Z. Ren   +39 more
semanticscholar   +1 more source

Hepatocellular carcinoma

The Lancet, 1999
Hepatocellular carcinoma (HCC) for most patients is a terminal complication of chronic inflammatory and fibrotic liver disease. With regrettably few exceptions, treatment is largely palliative, and long-term survival is rare. However, the major causes of HCC worldwide are known and preventable.
D F, Schafer, M F, Sorrell
openaire   +2 more sources

Hepatocellular carcinoma

Disease-a-Month, 2004
This year the number of papers published regarding hepatocellular carcinoma (HCC) continued to increase compared with last year, coinciding with an increase in incidence and awareness of this tumor.Molecular clock studies determined that hepatitis C-related HCC will continue to increase over the next 20 years mimicking the Japanese epidemic.
Joseph, Ahn, Steven L, Flamm
  +7 more sources

Hepatocellular carcinoma

Wiener Medizinische Wochenschrift, 2014
Hepatocellular carcinoma (HCC) is a heterogeneous tumor with many factors implicated in its development, with chronic infection and cirrhosis by hepatitis B virus (HBV) being the most prevalent. Cirrhosis due to metabolic syndrome, alcohol consumption, viral infection with hepatitis C virus (HCV) is also involved in its development.
Maria, Daoudaki, Ioannis, Fouzas
openaire   +3 more sources

EASL Clinical Practice Guidelines on the management of hepatocellular carcinoma.

Journal of Hepatology
Liver cancer is the third leading cause of cancer-related deaths worldwide, with hepatocellular carcinoma (HCC) accounting for approximately 90% of primary liver cancers.
Bruno Sangro   +10 more
semanticscholar   +1 more source

Hepatocellular carcinoma

The Lancet, 2018
Hepatocellular carcinoma appears frequently in patients with cirrhosis. Surveillance by biannual ultrasound is recommended for such patients because it allows diagnosis at an early stage, when effective therapies are feasible. The best candidates for resection are patients with a solitary tumour and preserved liver function.
Alejandro, Forner   +2 more
openaire   +2 more sources

Pembrolizumab in patients with advanced hepatocellular carcinoma previously treated with sorafenib (KEYNOTE-224): a non-randomised, open-label phase 2 trial.

The Lancet Oncology, 2018
BACKGROUND Immune checkpoint blockade therapy has shown promising results in patients with advanced hepatocellular carcinoma. We aimed to assess the efficacy and safety of pembrolizumab in this patient population.
A. Zhu   +20 more
semanticscholar   +1 more source

Hepatocellular Carcinoma

Clinics in Liver Disease, 2006
The number of patients who have hepatocellular carcinoma (HCC) is expected to more than double over the next 1 to 2 decades. Patients who have cirrhosis, regardless of cause, are at the highest risk for developing HCC. This article discusses surveillance of these patients for HCC by alpha-fetoprotein and ultrasound, evaluation using imaging ...
Jorge A, Marrero, Shawn, Pelletier
openaire   +2 more sources

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