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Outcomes of pleomorphic lobular carcinoma versus invasive lobular carcinoma

open access: yesBreast, 2019
Pleomorphic lobular carcinoma (PLC) is a rare histologic variant of invasive lobular carcinoma (ILC) that has been associated with worse clinical outcomes than classic ILC. Owing to its rarity, high-volume studies of its clinical characteristics and prognosis are lacking.
Sandra Hatch   +2 more
exaly   +3 more sources
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Lobular carcinoma in situ

Journal of Surgical Oncology, 1980
AbstractLobular carcinoma in situ remains controversial in nomenclature, histology, and therapy. The original description and therapeutic recommendations remain a significant contribution to better control of breast cancer. We believe the sophistication of mammography, not available at the time of the earliest therapeutic recommednations, provides the ...
R W, Powers, P H, O'Brien, A, Kreutner
openaire   +2 more sources

Mammography of Lobular Carcinoma

Radiology, 1963
Lobular carcinoma of the breast, first described as a separate entity in 1941 by Foote and Stewart (1, 9), represents an early stage in the development of mammary cancer (5, 6). Neoplastic cells slowly replace the epithelial cells of the lobule while its basic structure is retained (8).
A G, BORDEN, J, GERSHON-COHEN
openaire   +2 more sources

Lobular carcinoma in situ

European Journal of Cancer Prevention, 2008
The diagnosis of lobular carcinoma in situ (LCIS) provokes considerable anxiety in patients owing to misconceptions about this diagnosis. Initially LCIS was considered a premalignant lesion, but it is now a marker of increased risk. The number of women diagnosed with LCIS has increased in recent years most likely owing to more rigorous breast cancer ...
Nelia, Afonso, David, Bouwman
openaire   +2 more sources

Synchronous lobular carcinoma in situ and invasive lobular cancer: Marker or precursor for invasive lobular carcinoma

European Journal of Surgical Oncology, 2014
Lobular carcinoma in situ (LCIS) is a known risk factor for invasive breast carcinoma, but there is increasing data indicating a possible precursor relationship. This study investigates the incidence of lobular carcinoma in situ that occurs with invasive lobular carcinoma (ILC).Women diagnosed with ILC or LCIS from 2000 to 2010 were retrospectively ...
Philip S Dale, D Xiang
exaly   +3 more sources

Florid lobular carcinoma in situ: molecular profiling and comparison to classic lobular carcinoma in situ and pleomorphic lobular carcinoma in situ

Human Pathology, 2013
We evaluated genomic alterations and biomarker expression in 20 florid lobular carcinomas in situ using array-based comparative genomic hybridization and immunohistochemical analysis. The genetic characteristics of florid lobular carcinoma in situ were compared with 20 classic lobular carcinomas in situ and 21 pleomorphic lobular carcinomas in situ ...
Sandra J Shin   +2 more
exaly   +3 more sources

Infiltrating lobular carcinoma without lobular carcinoma in situ

Cancer, 1972
Seventeen patients had breast carcinoma with cell populations and histologic growth patterns identical to the infiltrating lobular carcinomas associated with lobular carcinoma in situ (CIS). However, no lobular CIS was demonstrable in the breasts.
openaire   +2 more sources

Lobular Carcinoma in Situ

2010
The reduced mortality from breast cancer seen in recent years is probably related to an accumulation of factors, including the use of aggressive multi-disciplinary treatment regimes, advances in our understanding of the cell biology of breast tumours and hence the development of targeted therapies, knowledge of the associated risk factors for ...
Da Silva, Leonard   +2 more
openaire   +4 more sources

Disseminated Lobular Carcinoma - A Predominantly Pleomorphic Lobular Carcinoma of the Whole Breast

Pathology - Research and Practice, 1980
Contrary to the usual distribution of lobular carcinoma in situ in a few lobules or terminal ducts, a case of disseminated lobular carcinoma is described occupying all lobules of the whole breast. The tumor developed in the left breast of a 61-year-old woman with the clinical symptoms of an increasing diffuse induration.
R, Bässler, H, Kronsbein
openaire   +2 more sources

Prognostic Value of Coexisting Lobular Carcinoma In Situ With Invasive Lobular Carcinoma

Applied Immunohistochemistry & Molecular Morphology, 2016
Aims and Objectives: Recent studies show that lobular carcinoma in situ (LCIS) and invasive lobular carcinoma (ILC) share similar genetic molecular biology. There are increasing concerns regarding the biological significance of LCIS.
Aparna, Harbhajanka   +7 more
openaire   +2 more sources

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