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Lobular carcinoma with cytoplasmic granules
Diagnostic Cytopathology, 2001AbstractWe report on a case of invasive lobular carcinoma of the breast with a previously undescribed cytologic feature. Diff‐Quik‐stained cytologic preparations showed uniform single cells with prominent coarse cytoplasmic granules. Ultrastructurally, the granules showed features suggestive of autophagosomes and/or degenerative mitochondria.
A, Vdovenko +3 more
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Absence of lobular carcinoma in situ is a poor prognostic marker in invasive lobular carcinoma
European Journal of Cancer, 2023To determine if the outcomes of patients with ILC co-occurring with LCIS are similar to pure ILC and if the presence of LCIS is a prognostic factor for ILC.In an observational, population-based investigation using data from the MD Anderson breast cancer prospectively collected electronic database, we analysed patients with a diagnosis of stage I-III ...
Jason A, Mouabbi +10 more
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[Lobular carcinoma in situ and lobular cancer (lobular carcinoma) of the breast].
Arkhiv patologii, 1977The histological characterization of mammary cancer (MC) is of leading importance for prognosis and choice of therapeutic methods (directed hormonal and chemotherapy). In this respect of interest is the morphological picture of a special form of MC, lobular cancer which is characterized by the most malignant course, marked infiltrative and less ...
Z V, Gol'bert, E E, Sorkin
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Lobular Lesions (Lobular Neoplasia, Invasive Lobular Carcinoma)
2017Lobular breast lesions described in this chapter encompass a spectrum of conditions that share in common a proliferation of neoplastic lobular-type cells, which are morphologically rounded, mostly uniform cells with a tendency for discohesion.
Puay Hoon Tan, Aysegul A. Sahin
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Lobular carcinoma in situ with microinvasion
Journal of Surgical Oncology, 1998Six patients with lobular carcinoma in situ with microinvasion were described in this report. Lobular carcinoma in situ is not known to progress to microinvasive disease. Although this feature is rare, the current under standing that lobular carcinoma in situ is a marker needs to be revised.
T, Nemoto +5 more
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Invasive Lobular Carcinoma of the Breast
Surgical Pathology Clinics, 2012Invasive lobular carcinoma of the breast is a distinct histologic type with specific clinical, radiologic, and microscopic features, which is increasing in incidence in the Western World. Routine pathologic prognostic factors, including grade, lymph node stage, and size are of significance in predicting outcome in this group of patients who, overall ...
Marianna, Philippidou, Sarah E, Pinder
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In Situ Lobular Carcinoma of the Breast
Archives of Surgery, 1981Nineteen patients who did not have mastectomy for in situ lobular carcinoma that was diagnosed by excisional biopsy were followed up for a period of seven to 21 years. In two patients, infiltrating carcinoma developed; each had mastectomies. They were followed up for 20 and 21 years.
E, Curletti, J, Giordano
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Infiltrating lobular carcinoma of the breast
Histopathology, 1982On review of the histology of 1050 primary breast carcinomas, 103 cases of infiltrating lobular carcinoma were identified and clinical and survival data collected in each case. The tumours were then separated into four groups on the basis of histological pattern and these groups shown to have significantly different survival times.
J M, Dixon +4 more
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Lobular carcinoma in situ of the breast
Seminars in Surgical Oncology, 1996Lobular carcinoma in situ (LCIS) of the breast is commonly identified as an incidental finding in breast biopsies performed because of either a mammographic abnormality or a palpable mass. Although long recognized as an entity, the significance and optimal treatment of LCIS remains controversial.
R A, Goldschmidt, T A, Victor
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Lobular carcinoma in situ and invasive lobular cancer of the breast
Current Opinion in Obstetrics and Gynecology, 2005The incidence of lobular carcinoma in situ and invasive lobular carcinoma of the breast is increasing. Recent data suggest that lobular carcinoma in situ is an indolent precursor for breast cancer, rather than a pure risk factor. This could imply free surgical margins become important.
Veronique, Cocquyt, Simon, Van Belle
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