Results 211 to 220 of about 104,892 (304)

Cancer Prevalence Among Large Cohort of Individuals With Down Syndrome: Implications for Screening Guidelines

Cancer Medicine, Volume 15, Issue 6, June 2026.
Individuals with Down syndrome have distinctive cancer profiles as compared with the general US population. Healthcare guidelines related to cancer screenings should reflect these unique profiles. ABSTRACT Introduction It is known that individuals with Down syndrome (DS) have a significantly different spectrum of malignancies and neoplasms.
Veronica Fitzpatrick, Akaninyene Noah, Anne Rivelli, Rachel Johnson, Melissa Zak, Joaquin Espinosa, Brian Chicoine   +6 more
wiley   +1 more source

Case Report: Intramyometrial uterine large-cell neuroendocrine carcinoma mimicking adenomyosis and leiomyomas with rapid fatal relapse. [PDF]

Front Oncol
Yi X, Yuan L, Sun S, An R.
europepmc   +1 more source

Penile Metastasis From Dedifferentiated Prostate Cancer With Low PSA Levels: A Case Report

Clinical Case Reports, Volume 14, Issue 6, June 2026.
ABSTRACT Penile metastasis from prostate cancer is rare and is associated with a poor prognosis; however, there is currently a lack of high‐level evidence to guide the management of this condition. This case report describes a 68‐year‐old male with prostate cancer who developed a penile metastasis during follow‐up. This occurred despite stable prostate‐
Xianqi Shen, Xinwen Nian, Bosi Zhang, Yan Wang, Zhenyang Dong, Min Qu, Xu Gao   +6 more
wiley   +1 more source

Rethinking the prognostic and biological significance of neuroendocrine marker expression in colorectal carcinoma. [PDF]

Front Endocrinol (Lausanne)
Mangogna A, Sabella G, Milione M.
europepmc   +1 more source

Homeobox B13 activates the hypoxia‐inducible factor 1 pathway through histone lactylation thereby reprogramming lipid metabolism and promoting sorafenib resistance in hepatocellular carcinoma

Journal of Cell Communication and Signaling, Volume 20, Issue 2, June 2026.
Lactylation‐mediated metabolism reprogramming in HCC sorafenib resistance. In sorafenib‐resistant hepatocellular carcinoma (HCC) cells, lactate accumulation drives histone H3 lysine 18 lactylation (H3K18la). This modification is specifically enriched in the promoter region of homeobox B13 (HOXB13), activating HOXB13 transcription and upregulating its ...
Qingqing Xie, Fangxia Teng, Ting Ding, Huaizhe Zhang, Jian Huang, Shu Zhang   +5 more
wiley   +1 more source

Primary pure small cell neuroendocrine carcinoma of the endometrium: a case report. [PDF]

J Med Case Rep
Gao S, Sun X.
europepmc   +1 more source

SIRT1: Protean roles at the nexus of health, disease, and therapeutics

Journal of Cell Communication and Signaling, Volume 20, Issue 2, June 2026.
SIRT1 serves as a central regulator linking metabolism, stress responses, and disease. It influences diverse processes, including transcriptional and posttranscriptional gene expression and protein activity, inflammation, mitochondrial function, and cell survival, through the deacetylation of multiple protein targets. While SIRT1 often plays protective
Brahim Chaqour
wiley   +1 more source

Diagnostic Utility of T-PIT, PIT-1, and SF-1 in Differentiating Pituitary Neuroendocrine Tumors From Sinonasal and Skull Base Tumors. [PDF]

Appl Immunohistochem Mol Morphol
Elsafy H, Lakis NS, Haeri M, Shrock DL, Bishop JA, Rooper LM, Stevens TM.   +6 more
europepmc   +1 more source

Fascia‐Fat‐Fascia “Sandwich Graft” Decreases Postoperative Cerebrospinal Fluid Leak Rate for High‐Flow Skull Base Defects

International Forum of Allergy &Rhinology, Volume 16, Issue 6, Page 646-649, June 2026.
Vidit M. Talati, Kathy Zhang, Kimberly X. Wei, Margaret B. Mitchell, Nithin D. Adappa, Michael A. Kohanski, Jennifer E. Douglas, Christina Jackson, John Y. K. Lee, Phillip B. Storm, Jillian W. Lazor, James N. Palmer   +11 more
wiley   +1 more source