Epigenetic evolution of bladder cancer from cellular origin to clinical translation
EpiTrace‐based lineage inference supports a proposed model in which TM4SF1‐positive plastic cancer subpopulations contribute to intratumoural heterogeneity and therapy resistance in bladder cancer. This framework links epigenetic tumour evolution to urine tumour DNA methylation‐based detection and conditionally reprogrammed cell‐based ex vivo drug ...
Kaiyu Qian +8 more
wiley +1 more source
Mixed Neuroendocrine-Non-Neuroendocrine Neoplasm of the Esophagogastric Junction with Enteroblastic Differentiation and Morphologic-Immunophenotypic Discordance: A Case Report with Five-Year Disease-Free Survival. [PDF]
Yoshizawa J +4 more
europepmc +1 more source
ABSTRACT Background Pancreatic adenocarcinoma (PDAC) is characterized by its poor prognosis. Cytology is essential for diagnostic confirmation and ancillary studies. The endoscopic ultrasound (EUS) set a precedent, facilitating cytological sampling through fine‐needle aspiration (FNA), with a sensitivity of 93% and a specificity of 95%.
Judith González‐López +10 more
wiley +1 more source
Endometrial Neuroendocrine Carcinoma With Widespread Metastases: Diagnostic and Therapeutic Challenges in a Rare Malignancy. [PDF]
Aswani A +4 more
europepmc +1 more source
Compared with the detection of either marker alone, the combined detection of calcitonin (Ctn) and carcinoembryonic antigen (CEA) improved the diagnostic accuracy for medullary thyroid cancer (MTC) but did not enhance the positive predictive value (PPV).
Yu Yang +22 more
wiley +1 more source
Early-Stage Rectal Mixed Neuroendocrine-Non-neuroendocrine Neoplasm Treated With Local Excision in a Frail Elderly Patient: A Multidisciplinary Management Dilemma. [PDF]
Ahmad CM +4 more
europepmc +1 more source
Bilateral multifocal renal neuroendocrine carcinoma with synchronous pancreatic neuroendocrine carcinoma and adrenal lesion. [PDF]
Huynh QH +4 more
europepmc +1 more source
ABSTRACT Introduction Thyroid cancer, the most prevalent endocrine malignancy globally, poses challenges owing to the limited understanding of its molecular drivers. Previous research has highlighted collagen genes, such as COL13A1 and COL23A1, as key players in thyroid cancer.
Md. Wahidul Islam +6 more
wiley +1 more source
Glutathione peroxidase 2 expression in human tumors: a tissue microarray study on 18,555 tumors. [PDF]
Chirico V +26 more
europepmc +1 more source

