Results 121 to 130 of about 825,494 (348)

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

Histological Transformation to Small Cell Carcinoma of an Adenosquamous Carcinoma of the Lung With Epidermal Growth Factor Receptor Mutation in Exons 20 and 21 After Treatment With Erlotinib: Case Report

Clinical Medicine Insights: Circulatory, Respiratory and Pulmonary Medicine, 2019
Lung carcinoma currently represents 1 of the leading causes of death from cancer worldwide and regionally. The molecular identification of sensitive mutations of targeted treatment have changed the strategies of pharmacologic management in non-small cell
Liliana Fernández-Trujillo, Laura Tapia, Marcela Vallejo, Marisol Aguirre, Juliana Lores, Luz F Sua   +5 more
doaj   +1 more source

Lung cancer biopsy: Can diagnosis be changed after immunohistochemistry when the H&E-Based morphology corresponds to a specific tumor subtype?

Clinics, 2018
OBJECTIVES: Advancements in non-small cell lung cancer treatment based on targeted therapies have made the differentiation between adenocarcinoma and squamous cell carcinoma increasingly important.
Fabiola Del Carlo Bernardi, Marcela Del Carlo Bernardi, Teresa Takagaki, Sheila Aparecida Coelho Siqueira, Marisa Dolhnikoff   +4 more
doaj   +1 more source

Changes on Mitochondrial DNA Content in Non-small Cell Lung Cancer [PDF]

, 2011
Background and objective It has been proven that the mitochondrial DNA (mtDNA) mutations and content change were associated with increasing risk of tumorigenesis. MtDNA content is significantly reduced in most substantive tumors. The aim of this study is
Hongmei WANG, Jigang DAI
core  

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Non-Small Cell Lung Carcinoma with Concomitant Localized Pulmonary Melioidosis: A Rare Co-Existing Disease

Infection and Drug Resistance, 2020
Gunthiga Laplertsakul,1 Yuda Sutherasan,1 Thitiporn Suwatanapongched,2 Pimpin Incharoen,3 Tananchai Petnak1 1Division of Pulmonary and Pulmonary Critical Care Medicine, Department of Medicine, Faculty of Medicine Ramathibodi Hospital, Mahidol University,
Laplertsakul G, Sutherasan Y, Suwatanapongched T, Incharoen P, Petnak T   +4 more
doaj  

Basic and Clinical Aspects of Non-neuronal Acetylcholine: Expression of Non-neuronal Acetylcholine in Lung Cancer Provides a New Target for Cancer

Journal of Pharmacological Sciences, 2008
Lung cancer is the leading cause of cancer death worldwide and new treatment strategies are clearly needed. The recent discovery that lung and other cancers synthesize and secrete acetylcholine (ACh) which acts as an autocrine growth factor suggests that
Therapy Pingfang Song, Eliot R. Spindel
doaj   +1 more source

Submicron silica particles have cytotoxicities on hepatocellular carcinoma, non-small cell lung cancer and breast cancer by unified regulating the XLOC_001659/miR-98-5p/MAP3K2-mediated pathway. [PDF]

Toxicol Res (Camb), 2021
Shi J, Ci Y, Zheng Y, Chen W, Chen X.
europepmc   +1 more source

bcl-2 Protein in Non-Small-Cell Lung Carcinoma

New England Journal of Medicine, 1993
The proto-oncogene bcl-2 encodes a protein that inhibits programmed cell death (apoptosis). The protein is expressed in basal cells in normal human epithelium, but no data are available on the frequency or clinical importance of its expression in carcinoma.
Pezzella, F, Turley, H, Kuzu, I, Tungekar, M, Dunnill, MS, Pierce, C, Harris, A, Gatter, K, Mason, D   +8 more
openaire   +3 more sources

Predicting non-small cell lung cancer prognosis by fully automated microscopic pathology image features

Nature Communications, 2016
Lung cancer is the most prevalent cancer worldwide, and histopathological assessment is indispensable for its diagnosis. However, human evaluation of pathology slides cannot accurately predict patients’ prognoses.
Kun‐Hsing Yu, Ce Zhang, G. Berry, R. Altman, Christopher Ré, D. Rubin, M. Snyder   +6 more
semanticscholar   +1 more source