Somatically derived ovarian yolk sac tumor in a postmenopausal woman: A case report of durable remission with personalized chemotherapy. [PDF]
Popat V +4 more
europepmc +1 more source
Irreversible ECM proteolysis by remodeling enzymes shapes development, homeostasis, and disease. ECM‐degrading proteases display cell specificity and are governed by shared mechanisms, exhibiting functional redundancy in generating matrikines, growth factors, and cytokines.
Inna Solomonov, Orit Kollet, Irit Sagi
wiley +1 more source
Two Giant Cystic Uterine Adenomyomas in a Premenopausal Woman: The Largest Case to Date With Immunohistochemical Findings. [PDF]
Kitami K +7 more
europepmc +1 more source
A guide to the types, structures, and multifaceted functions of matrix metalloproteinases in cancer
Matrix metalloproteinases (MMPs) orchestrate cancer progression and metastasis through proteolytic and non‐proteolytic actions. By remodeling the tumor microenvironment, enhancing growth factor availability, and modulating cell behavior, MMPs promote proliferation, migration or invasion, and epithelial‐to‐mesenchymal transition. Alongside extracellular
Zoi Piperigkou +4 more
wiley +1 more source
Ovarian Tumor Biomarkers: Correlation Between Tumor Type and Marker Expression, and Their Role in Guiding Therapeutic Strategies. [PDF]
Gawełczyk W +6 more
europepmc +1 more source
PAX8 expression in urothelial carcinoma was investigated in 101 consecutive transurethral resections of the urinary bladder. PAX8 was positive in 10% of cases, with targeted molecular testing of these cases revealing universal TERT promoter mutations and frequent alterations in TSC1, NOTCH1 and WT1. Aims PAX8 immunohistochemistry (IHC) is often used to
Sarah Mae Lammert +5 more
wiley +1 more source
Functional miRNA Transfer in Models of Serous Ovarian Carcinoma. [PDF]
Muralidhar GG +4 more
europepmc +1 more source
Identification and characterization of a homozygous deletion found in ovarian ascites by representational difference analysis [PDF]
Gabra, H +7 more
core
Vaginal Microbiota and Ovarian Cancer: A New Frontier in Immunomodulation and Diagnosis
Microbial imbalance, dysbiosis, plays a role in ovarian carcinogenesis by interacting with the immune system and altering inflammatory pathways, notably Th17 pathways. In contrast, eubiosis, characterised by Lactobacillus dominance, protects against infections and maintains hormone metabolism.
Wafa Babay +4 more
wiley +1 more source
Expression of concern: CD117 expression in fibroblasts-like stromal cells indicates unfavorable clinical outcomes in ovarian carcinoma patients. [PDF]
PLOS One Editors.
europepmc +1 more source

