Results 51 to 60 of about 361,742 (335)

Mucins as a factor of carcinogenesis and a potential target for therapy of mucinous ovarian tumors

Опухоли женской репродуктивной системы
Mucinous ovarian carcinoma is a rare histological form of epithelial ovarian cancer. These tumors demonstrate poor objective response to standard chemotherapy regimens for epithelial ovarian cancer and PARP inhibitors maintenance therapy, resulting in ...
A. G. Kedrova, T. A. Greyan
doaj   +1 more source

Activation of MAPK signalling results in resistance to saracatinib (AZD0530) in ovarian cancer [PDF]

, 2017
SRC tyrosine kinase is frequently overexpressed and activated in late-stage, poor prognosis ovarian tumours, and preclinical studies have supported the use of targeted SRC inhibitors in the treatment of this disease.
El-Helali, Aya, Kennedy, Richard D., McCabe, Nuala, McGivern, Niamh, Mcneish, Iain A., Mullan, Paul, Paul Harkin, D   +6 more
core   +2 more sources

Serum microRNA-92 expression in patients with ovarian epithelial carcinoma

Journal of International Medical Research, 2013
Objectives Studies have reported the significance of circulating microRNAs (miRNAs) as biochemical markers of cancer. Few reports demonstrate the significance of miRNAs in the serum of patients with ovarian epithelial carcinoma (EOC).
F. Guo, Jingyan Tian, Yang Lin, Yuemei Jin, Ling Wang, M. Cui   +5 more
semanticscholar   +1 more source

Bilateral mucinous ovarian carcinoma in a young female with tumor weighing 41.1 kg

Journal of Family Medicine and Primary Care, 2022
Mucinous ovarian carcinoma is a less-prevalent subtype of epithelial tumors. We present a case of giant mucinous ovarian carcinoma weighing 41.1 kg in a 24-year-old Indian girl. Benign mucinous tumors have the potential to reach an enormous size but such
Kavita Khoiwal, Payal Kumari, Deepika Dhundi, Om Kumari, Anshu Gupta, Priyanka Gupta, Sonu Sama, Pankaj Sharma, Michael Anthony, Amrita Gaurav, Jaya Chaturvedi   +10 more
doaj   +1 more source

Apoptotic and chemotherapeutic properties of iron(III)-salophene in an ovarian cancer animal model [PDF]

, 2008
The cytotoxicity of organometallic compounds iron(III)-, cobalt(III)-, manganese(II)-, and copper(II)-salophene (-SP) on platinum-resistant ovarian cancer cell lines was compared. Fe-SP displayed selective cytotoxicity (IC 50 at ∼1 μM) against SKOV-3 and
Alptürk, O, Brard, L, Kyu, KK, Lange, TS, Luisi, BS, McCourt, C, Singh, AP, Singh, RK, Strongin, RM   +8 more
core   +3 more sources

Expression of IL-18, IL-18 Binding Protein, and IL-18 Receptor by Normal and Cancerous Human Ovarian Tissues: Possible Implication of IL-18 in the Pathogenesis of Ovarian Carcinoma

Mediators of Inflammation, 2014
Proinflammatory cytokine IL-18 has been shown to be elevated in the sera of ovarian carcinoma patients. The aim of the study was to examine the levels and cellular origin of IL-18, IL-18 binding protein, and IL-18 receptor in normal and cancerous ovarian
Liat Medina, Alex Rabinovich, Benjamin Piura, Victor Dyomin, Ruthy Shaco Levy, Mahmoud Huleihel   +5 more
doaj   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

Immuno-reactivity of Engrailed (EN)-2 in Epithelial Ovarian Neoplasms [PDF]

Research in Oncology
Background: Ovarian neoplasm refers to any tumor that originates primarily in the ovary. Epithelial ovarian neoplasms are the most common type of ovarian tumor and are classified based on their histogenetic and immunophenotypic features.
Noha Hassab El-Naby, Amr Abdelkareem, Hatem Awaga, Alshimaa Abdelall, Maisa Mohammed   +4 more
doaj   +1 more source

The diagnostic accuracy of two human epididymis protein 4 (HE4) testing systems in combination with CA125 in the differential diagnosis of ovarian masses [PDF]

, 2011
Background: Cancer antigen 125 (CA125) is the best known single tumor marker for ovarian cancer (OC). We investigated whether the additional information of the human epididymis protein 4 (HE4) improves diagnostic accuracy.
Burges, Alexander, Fuerst, Sophie, Hertlein, Linda, Hofmann, Karin, Kirschenhofer, Angela, Krocker, Katja, Lenhard, Miriam, Mayr, Doris, Nagel, Dorothea, Stieber, Petra   +9 more
core   +1 more source

RhoC is a major target of microRNA-93-5P in epithelial ovarian carcinoma tumorigenesis and progression

Molecular Cancer, 2015
BackgroundAn increasing amount of evidence has revealed that microRNAs regulate various biological processes, including cell differentiation, cell proliferation, apoptosis, drug resistance, and fat metabolism.
Xi Chen, Shuo Chen, Yin-ling Xiu, K. Sun, Z. Zong, Yang Zhao   +5 more
semanticscholar   +1 more source