Results 221 to 230 of about 92,469 (306)

Painful penile erection as a manifestation of metastatic pancreatic ductal adenocarcinoma. [PDF]

open access: yesClin J Gastroenterol
Mori H   +9 more
europepmc   +1 more source

Simvastatin Restores Cisplatin Sensitivity by Suppressing the Caveolin‐1‐Mediated PI3K/AKT Signaling Pathway in Cisplatin‐Resistant Cervical Cancer Cells

open access: yesThe FASEB Journal, Volume 40, Issue 9, 15 May 2026.
Simvastatin synergizes with cisplatin in cisplatin‐resistant cervical cancer cells through suppression of the caveolin‐1‐mediated PI3K/AKT signaling axis. ABSTRACT Cervical cancer treatment is often hindered by the emergence of cisplatin (DDP) resistance. Increasing evidence has indicated that statins possess anti‐tumor and chemosensitization potential
Yujia Zhou   +7 more
wiley   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, Volume 20, Issue 5, Page 1253-1269, May 2026.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

Portuguese Pancreatic Club Perspective on Epidemiology, Classification, and Natural History of Pancreatic Intraductal Papillary Mucinous Neoplasms. [PDF]

open access: yesGE Port J Gastroenterol
Bravo AC   +7 more
europepmc   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, Volume 20, Issue 5, Page 1237-1252, May 2026.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

Radiotherapy Enhancement by Gold Nanocluster‐functionalized Nanoliposomes Using Polychromatic Orthovoltage X‐ray Irradiation

open access: yesAdvanced Materials Interfaces, Volume 13, Issue 9, 5 May 2026.
Lipid drug carriers to which ultra‐small gold nanoparticles were added enabled more efficient radiotherapy of cultured pancreatic cancer tumors. These nanoparticles boosted radiation‐induced damage to tumors by generating more reactive molecules, though higher gold levels are needed for strong benefits.
Nazareth Milagros Carigga Gutierrez   +17 more
wiley   +1 more source

Early Radiation Therapy Response Assessment Using Multi‐Scale Photoacoustic Imaging

open access: yesAdvanced Science, Volume 13, Issue 26, 8 May 2026.
Tomographic and mesoscopic photoacoustics capture intratumoural features of radioresistance and response. ABSTRACT There is a critical unmet clinical need to identify biomarkers that predict and detect radiation therapy (RT) response in cancer. Using the unique capabilities of multi‐scale photoacoustic imaging (PAI) to depict tumor oxygenation and ...
Thierry L. Lefebvre   +12 more
wiley   +1 more source

Synchronous Pancreatic Ductal Adenocarcinoma and Thyroid Medullary Carcinoma

open access: yesHaydarpasa Numune Training and Research Hospital Medical Journal, 2017
openaire   +2 more sources

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