Results 231 to 240 of about 63,783 (265)

Interaction of pancreatic ductal carcinoma with nerves leads to nerve damage

Gastroenterology, 1994
Perineural extension of pancreatic adenocarcinoma has been explained as a mechanical extension along planes of least resistance. This study tests whether the cancer is limited to following these planes and if substances involved in cell signaling are involved in the interaction of cancer cells with nerves.Samples of tissue from patients undergoing ...
D E, Bockman, M, Büchler, H G, Beger
openaire   +2 more sources

Remnant Pancreatectomy for Pancreatic Ductal Carcinoma

HPB, 2022
D. Nagashima, M. Esaki, D. Ban, S. Nara, T. Takamoto, T. Mizui, K. Shimada   +6 more
openaire   +1 more source

The molecular genetics of pancreatic ductal carcinoma.

Minerva chirurgica, 2003
Pancreatic ductal carcinoma remains the 4th leading cause of cancer death in both men and women in the United States, with an overall 5-year survival of less than 3%. Over the last decade, significant advances have been made in our understanding of the molecular biology of pancreatic ductal carcinoma, with pancreatic cancer now considered one of the ...
openaire   +1 more source

Endocrine and intermediate cells in pancreatic ductal carcinoma and in chronic pancreatitis.

Roczniki Akademii Medycznej w Bialymstoku (1995), 2003
As most pancreatic ductal carcinomas have the genotype of ductal epithelial cells it is believed that they originate from the epithelium of these structures. It has been proved that endocrine cells are frequently present in ductal carcinoma. Morphological, immunohistochemical, ultrastructural evaluation and statistical analysis revealed the presence of
Beata, Szynaka, Lech, Zimnoch, Zbigniew, Puchalski, Piotr, Szynaka   +3 more
openaire   +1 more source

[Intraductal intraepithelial neoplasia and ductal pancreatic carcinoma].

Arkhiv patologii, 2006
The review of modern achievements in morphology and genetic characteristics of pancreatic tumors with ductal phenotype is presented. Problems of intraductal pancreatic neoplasia (PanIN) as precancerous process for ductal adenocarcinoma are considered in detail.
G A, Galil-Ogly, O V, Paklina, V V, Tsvirkun   +2 more
openaire   +1 more source

The molecular genetics of pancreatic ductal carcinoma: a review.

Surgical oncology, 2001
In the last several years, numerous advances in the field of molecular genetics have been applied to pancreatic ductal carcinoma- the 5th leading cause of cancer death in the United States. This review summaries the current knowledge about adenocarcinoma of the pancreas.
T A, Sohn, C J, Yeo
openaire   +1 more source

Pen2/ErbB4 signaling regulates stemness of pancreatic ductal carcinoma

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
Cancer stem cells (CSCs) are critical for progression, invasion, metastasis, and chemotherapy resistance of pancreatic ductal adenocarcinoma (PDAC). Presenilin enhancer 2 (Pen2), a vital component of the gamma-secretase complex, is overexpressed in various cancers and plays a significant role in carcinogenesis.
Zhongfei, Zhu, Dan, Ding, Hao, Hu, Tianlin, He   +3 more
openaire   +2 more sources

Relevant factors in the prognosis of ductal pancreatic carcinoma.

Acta chirurgica Scandinavica, 1991
Because it is important to assess relevant prognostic factors when deciding which patients will profit from pancreatic resection and which will not, 484 patients with ductal pancreatic carcinoma who were operated on between 1 January 1978 and 31 December 1987 in the Department of General and Abdominal Surgery of Mainz Medical School were studied ...
T, Böttger, J, Zech, W, Weber, K, Sorger, T, Junginger   +4 more
openaire   +1 more source

[Neoadjuvant and adjuvant therapy of ductal pancreatic carcinoma].

Zentralblatt fur Chirurgie, 2000
The optimal oncological management of ductal pancreatic cancer remains undefined. More than 60% of these patients have disseminated disease at the time of presentation. Here radical surgery alone cannot guarantee a cure. Even in the best case of a R0-resection with extended lymph node dissection the reported 5-year survival rates of 20-30% are ...
W, Hohenberger, S, Kastl
openaire   +1 more source

Proteogenomic characterization of pancreatic ductal adenocarcinoma

Cell, 2021
Christopher R Kinsinger, Ana I Robles, David Fenyö   +2 more
exaly