Results 251 to 260 of about 64,621 (307)

Exosomal miR‐4644 Targets SPRY3 to Promote Proliferation and Invasion of Pancreatic Cancer

open access: yesCancer Medicine, Volume 15, Issue 6, June 2026.
ABSTRACT Background Tumor‐derived exosomes (TDEs) can carry diverse genetic material that modulates pancreatic cancer (PC) proliferation and invasion. Despite this, the involvement of microRNAs (miRNAs) in TDE‐mediated tumor progression in PC remains inadequately explored. Methods Ultracentrifugation was used to isolate exosomes derived from AsPC‐1 and
Xiangyu Chu   +8 more
wiley   +1 more source

Role of SCAP in regulation of pancreatic homeostasis, pancreatitis, and tumorigenesis. [PDF]

open access: yesOncogene
Lilly AC   +8 more
europepmc   +1 more source

High Sensitivity ctDNA Analysis Using a Novel Panel and NOIR‐SS Technology for Monitoring Advanced Urothelial Carcinoma

open access: yesCancer Medicine, Volume 15, Issue 6, June 2026.
ABSTRACT Advanced urothelial carcinoma (aUC) has a poor prognosis, and real‐time monitoring of treatment response remains clinically challenging. Circulating tumor DNA (ctDNA) has emerged as a promising non‐invasive biomarker that may reflect tumor burden and molecular response.
Tetsuya Danno   +12 more
wiley   +1 more source

Identification of Novel Small‐Molecule Inhibitors Targeting KDM5B and Evaluation of Their Antitumour Effects

open access: yesCancer Medicine, Volume 15, Issue 6, June 2026.
ABSTRACT KDM5B, a member of the KDM5 family of histone demethylases, plays a critical role in transcriptional repression by demethylating H3K4me2/3. It regulates key biological processes such as development, stem cell maintenance, and oncogenesis, and its aberrant expression is implicated in various cancers. Accordingly, KDM5B is considered a promising
Tomoaki Hara   +16 more
wiley   +1 more source

Cervical Skip Metastases and Extensive Central Venous Thrombosis as the Initial Presentation of High‐Grade Prostate Adenocarcinoma With Discordant PI‐RADS 3 Findings: A Case Report and Diagnostic Challenge

open access: yesClinical Case Reports, Volume 14, Issue 6, June 2026.
ABSTRACT Prostate cancer can initially present with cervical lymph node “skip” metastases and extensive central venous thrombosis, without pelvic or bone involvement. A PI‐RADS 3 lesion on mpMRI does not exclude high‐grade (Gleason 5 + 5 = 10) disease. Unexplained thrombosis in elderly men warrants prostate cancer investigation.
Yuchun Luo, Benhui Lai, Juncheng Huang
wiley   +1 more source

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