Results 31 to 40 of about 89,882 (308)

A Case of Pancreatic Intraepithelial Neoplasia That Was Difficult to Diagnose Preoperatively

Case Reports in Oncology, 2015
A 63-year-old female patient presented to a local physician with pain in her back and epigastric region. An abdominal computed tomography (CT) scan revealed a pancreatic tumor, and the patient was referred to our hospital.
Hiroyuki Ito, Yoshiaki Kawaguchi, Yohei Kawashima, Atsuko Maruno, Masami Ogawa, Kenichi Hirabayashi, Tetsuya Mine   +6 more
doaj   +1 more source

An integrative approach unveils FOSL1 as an oncogene vulnerability in KRAS-driven lung and pancreatic cancer [PDF]

, 2017
KRAS mutated tumours represent a large fraction of human cancers, but the vast majority remains refractory to current clinical therapies. Thus, a deeper understanding of the molecular mechanisms triggered by KRAS oncogene may yield alternative ...
Andersen, Jesper B., Arricibita, Andrea, Bailey, Peter, Biankin, Andrew, Bozec, Aline, Chang, David K., Chuang, Chen-Hua, Guembe, Laura, Guruceaga, Elisabet, Gwinn, Dana, Khatri, Purvesh, Lecanda, Fernando, Martinez-Canarias, Susana, Mazur, Pawel K., Perurena, Naiara, Ponz-Sarvise, Mariano, Sage, Julien, Sayles, Leanne C., Sweet-Cordero, E. Alejandro, Valencia, Karmele, Vallejo, Adrian, Vicent, Silve, Zandueta, Carolina   +22 more
core   +3 more sources

Emerging therapies for pancreatic ductal carcinoma

Journal of Solid Tumors, 2016
Pancreatic ductal adenocarcinoma (PDAC) is a solid tumor mass that grows and metastasizes rapidly. There are no definitivemethods for early detection and most patients are diagnosed at a late stage. Those diagnosed at an early stage are eligible for tumorresection. However, many of these patients are soon burdened with tumor recurrence. The tumor grows
Robert Falcone, Paul J. Davis, Steven C. Stain, Shaker A. Mousa   +3 more
openaire   +2 more sources

A case of pancreatic ductal adenocarcinoma with marked infiltration with IgG4-positive cells

Journal of Cytology, 2013
A 75-year-old man was diagnosed as having pancreatic ductal carcinoma containing remarkable lymphocytic and plasma cell infiltration, as revealed by the cytological examination of endoscopic ultrasound guided fine-needle aspiration (EUS-FNA) specimen ...
M Yoneda, H Inada, K Kanayama, T Shiraishi   +3 more
doaj   +1 more source

Pictorial Review of Rare Pancreatic Tumors and Tumor-Like Lesions

대한영상의학회지, 2020
Various types of tumors and tumor-like lesions may affect the pancreas. Among them, pancreatic ductal adenocarcinoma is the most common and is generally referred to as “pancreatic cancer.” Recently, the detection rates of rare pancreatic tumors and ...
Seung Jae Lee, Sang Soo Shin, Suk Hee Heo, Yong Yeon Jeong   +3 more
doaj   +1 more source

Experimental trial for diagnosis of pancreatic ductal carcinoma based on gene expression profiles of pancreatic ductal cells [PDF]

Cancer Science, 2005
Pancreatic ductal carcinoma (PDC) remains one of the most intractable human malignancies, mainly because of the lack of sensitive detection methods. Although gene expression profiling by DNA microarray analysis is a promising tool for the development of such detection systems, a simple comparison of pancreatic tissues may yield misleading data that ...
Madoka, Ishikawa, Koji, Yoshida, Yoshihiro, Yamashita, Jun, Ota, Shuji, Takada, Hiroyuki, Kisanuki, Koji, Koinuma, Young Lim, Choi, Ruri, Kaneda, Toshiyasu, Iwao, Kiichi, Tamada, Kentaro, Sugano, Hiroyuki, Mano   +12 more
openaire   +2 more sources

Anaplastic carcinoma of the pancreas diagnosed by endoscopic ultrasound-guided fine-needle aspiration: a case report and review of the literature

Journal of Medical Case Reports, 2018
Background Anaplastic carcinoma of the pancreas is a rare pancreatic neoplasm with a poor prognosis. It is classified as a variant of ductal adenocarcinoma, but the clinical features and treatment of it remain unknown because of its rarity and ...
Kohei Oka, Ken Inoue, Satoshi Sugino, Taishi Harada, Toshifumi Tsuji, Shingo Nakashima, Takayuki Katayama, Takashi Okuda, Syuichi Kin, Akihiro Nagata, Toshiyuki Komaki, Keizo Kagawa   +11 more
doaj   +1 more source

Challenges of drug resistance in the management of pancreatic cancer [PDF]

, 2010
The current treatment of choice for metastatic pancreatic cancer involves single agent gemcitabine or combination of gemcitabine with capecitabine and erlotinib (tyrosine kinase inhibitor).
Akada, Allison, Almoguera, Andreetta, Arai, Arlt, Arteaga, Arumugam, Asano, Bachem, Baldwin, Banerjee, Bartsch, Bergers, Best, Bold, Bondar, Buck, Burris, Chakravarti, Chakravarti, Choi, Cunningham, Cunningham, Dancer, Dong, Duxbury, Duxbury, Duxbury, Duxbury, Engelman, Feldmann, Ferrero, Galmarini, Geyer, Giovannetti, Goan, Greer, Hagmann, Hahn, Henke, Hruban, Humeniuk, Ischenko, Ishikawa, Itoi, Jansen, Karapetis, Kindler, Kong, Koopman, Kulik, Lei, Lemoine, Liau, Liau, Longley, Mackey, Mackey, Mackey, Mahon, Mamaghani, Marechal, Marmor, Martin Clynes, Mata, Maxwell, Mendelsohn, Meropol, Miwa, Moertel, Molina-Arcas, Moore, Morgillo, Moriyama, Muerkoster, Muerkoster, Nakahira, Nakajima, Nakano, Naomi Walsh, Nishimura, Oguri, Okamoto, Okumura, Olive, O’Driscoll, Pao, Park, Park, Peters, Plunkett, Ray McDermott, Ritzel, Rizwan Sheikh, Robert O’Connor, Ruggeri, Safran, Saito, Sakamoto, Schuller, Sebastiani, Shah, Shi, Simon, Spratlin, Takao, Takebayashi, Treat, Tsukamoto, Tzeng, Vaishampayan, Van Cutsem, van der Wilt, Wang, Wang, Wang, Xiong, Yamasaki, Yokoi   +119 more
core   +1 more source

Screening of genes specifically activated in the pancreatic juice ductal cells from the patients with pancreatic ductal carcinoma [PDF]

Cancer Science, 2003
Pancreatic ductal carcinoma (PDC) is one of the most intractable human malignancies. Surgical resection of PDC at curable stages is hampered by a lack of sensitive and reliable detection methods. Given that DNA microarray analysis allows the expression of thousands of genes to be monitored simultaneously, it offers a potentially suitable approach to ...
Koji, Yoshida, Shuichi, Ueno, Toshiyasu, Iwao, Souichirou, Yamasaki, Akira, Tsuchida, Ken, Ohmine, Ruri, Ohki, Young Lim, Choi, Koji, Koinuma, Tomoaki, Wada, Jun, Ota, Yoshihiro, Yamashita, Kazuaki, Chayama, Kazuhiro, Sato, Hiroyuki, Mano   +14 more
openaire   +2 more sources

Molecular drivers and cells of origin in pancreatic ductal adenocarcinoma and pancreatic neuroendocrine carcinoma [PDF]

Experimental Hematology & Oncology, 2020
AbstractPancreatic cancer is one of the most common causes of cancer-related deaths worldwide. The two major histological subtypes of pancreatic cancer are pancreatic ductal adenocarcinoma (PDAC), accounting for 90% of all cases, and pancreatic neuroendocrine neoplasm (PanNEN), which makes up 3–5% of all cases.
He-Li Gao, Wen-Quan Wang, Xian-Jun Yu, Liang Liu   +3 more
openaire   +3 more sources