RelA regulates CXCL1/CXCR2-dependent oncogene-induced senescence in murine Kras-driven pancreatic carcinogenesis [PDF]
Tumor suppression that is mediated by oncogene-induced senescence (OIS) is considered to function as a safeguard during development of pancreatic ductal adenocarcinoma (PDAC). However, the mechanisms that regulate OIS in PDAC are poorly understood. Here,
Algül, Hana +17 more
core +1 more source
Multidetector computer tomography in the pancreatic adenocarcinoma assessment: an update
Ductal adenocarcinoma of the pancreas is one of the most aggressive forms of cancer, with only a minority of cases being resectable at the moment of their diagnosis.
Vincenza Granata +10 more
doaj +1 more source
Regulation of pancreatic cancer aggressiveness by stromal stiffening [PDF]
No abstract ...
A Neesse +13 more
core +1 more source
Emerging therapies for pancreatic ductal carcinoma
Pancreatic ductal adenocarcinoma (PDAC) is a solid tumor mass that grows and metastasizes rapidly. There are no definitivemethods for early detection and most patients are diagnosed at a late stage. Those diagnosed at an early stage are eligible for tumorresection. However, many of these patients are soon burdened with tumor recurrence. The tumor grows
Robert Falcone +3 more
openaire +2 more sources
Pancreatic Metastasis of Breast Cancer: A Rare Cause of Obstructive Jaundice
The pancreas is a rare site of metastasis from malignant tumours. Pancreatic metastasis accounts for less than 5% of all pancreatic malignancies. The most common malignancies metastasizing to pancreas are the renal cell carcinoma, non-small cell lung ...
Mutahir A. Tunio +3 more
doaj +4 more sources
A Case of Pancreatic Intraepithelial Neoplasia That Was Difficult to Diagnose Preoperatively
A 63-year-old female patient presented to a local physician with pain in her back and epigastric region. An abdominal computed tomography (CT) scan revealed a pancreatic tumor, and the patient was referred to our hospital.
Hiroyuki Ito +6 more
doaj +1 more source
Clinical and molecular characterization of HER2 amplified-pancreatic cancer [PDF]
<p>Background: Pancreatic cancer is one of the most lethal and molecularly diverse malignancies. Repurposing of therapeutics that target specific molecular mechanisms in different disease types offers potential for rapid improvements in outcome ...
Biankin, A.V. +27 more
core +3 more sources
A case of pancreatic ductal adenocarcinoma with marked infiltration with IgG4-positive cells
A 75-year-old man was diagnosed as having pancreatic ductal carcinoma containing remarkable lymphocytic and plasma cell infiltration, as revealed by the cytological examination of endoscopic ultrasound guided fine-needle aspiration (EUS-FNA) specimen ...
M Yoneda +3 more
doaj +1 more source
Pictorial Review of Rare Pancreatic Tumors and Tumor-Like Lesions
Various types of tumors and tumor-like lesions may affect the pancreas. Among them, pancreatic ductal adenocarcinoma is the most common and is generally referred to as “pancreatic cancer.” Recently, the detection rates of rare pancreatic tumors and ...
Seung Jae Lee +3 more
doaj +1 more source
Recent Developments in the Treatment of Pancreatic Cancer
Pancreatic duct adenocarcinoma is currently the sixth-leading cause of cancer death worldwide and the fourth in Europe, with a continuous increase in annual lethality in Portugal during the last two decades.
Jorge Paulino, Hélder Mansinho
doaj +1 more source

