Results 121 to 130 of about 1,472,301 (348)

Pediatric Renal Cell Carcinoma [PDF]

Surgical Pathology Clinics, 2010
Renal cell carcinomas are rare in children, and they show significant differences in their histology and pathogenesis when compared to those common in adults. The most common subtypes seen preferentially in children are the translocation-associated tumors, papillary renal cell carcinoma, renal medullary carcinoma, and oncocytic renal cell carcinoma ...
openaire   +2 more sources

TRMT6‐Mediated m1A Modification of CDK9 mRNA Is a Dual‐Pronged Pathogenic Driver for HBV‐Related Hepatocellular Carcinoma

Advanced Science, EarlyView.
TRMT6‐mediated m1A modification in CDK9 mRNA enhances its mRNA stability and translation efficiency, thereby increasing the protein levels of CDK9. Upregulated CDK9 promotes the progression of HCC by elevating the levels of oncogenic factors including p‐STAT3, MCL1, and BCL‐2. On the other hand, CDK9 phosphorylates TARDBP at Ser254 to activate HBV core
Rui Zhang, Dandan Zong, Rui Liu, Yubo Wang, Qingqing Gu, Yao Yao, Wenfang Zheng, Mengmeng Yuan, Simeng Wang, Rongrong Cui, Daxu Li, Siwen Dang, Peng Hou   +12 more
wiley   +1 more source

Metachronous renal cell carcinoma with metastasis to the urinary bladder, and distant organs, 28 years after radical nephrectomy: a case report

BMC Urology, 2019
Background Metachronous renal cell carcinoma after radical nephrectomy is extremely rare. Renal cell carcinoma commonly metastasizes to distant organs. However, metastasis to the urinary bladder is very uncommon.
Mustufa Babar, Saad Hamdani, Corinne Liu, Jogarao Vedula, David S. Schnapp   +4 more
doaj   +1 more source

Efficacy of temsirolimus in metastatic chromophobe renal cell carcinoma [PDF]

, 2013
<p>Background: Renal cell carcinoma (RCC) is a histopathologically and molecularly heterogeneous disease with the chromophobe subtype (chRCC) accounting for approximately 5% of all cases.
A Armstrong, A Jemal, B Paule, B Shuch, Balaji Venugopal, D Zardavas, G Hudes, G Kovacs, J Dutcher, J-J Patard, Jawaher Ansari, JMG Larkin, Lye Mun Tho, ME Gore, Michael Aitchison, PH Patel, RJ Motzer, RJ Motzer, Rob J Jones, Roderick Campbell, SK Tickoo, TK Choueiri   +21 more
core   +1 more source

Consumed by Abdominal Distention

Arthritis Care &Research, EarlyView.
Abimbola Fadairo‐Azinge, James Grenert, Brian Haas, Mary Margaretten   +3 more
wiley   +1 more source

Paving the Way to Elucidate Hg's Role in Tumorigenesis

Advanced Science, EarlyView.
Tumorigenesis can result from diverse environmental carcinogens. Among them, mercury—a lifelong bioaccumulative Group 2B carcinogen—has tumorigenic potential that remains poorly understood due to confounding co‐exposures and limited organ‐specific data.
Shouying Li, Rong Zhong, Zhenyang Yu, Hualing Fu, Jin Chen, Jia Wei, Ningwei Zhao, Le Qu, Tiantian Li, Wenli Tang, Huan Zhong   +10 more
wiley   +1 more source

Clear Cell Papillary Renal Cell Carcinoma in the Bilateral Native Kidneys after 2 Years of Renal Transplantation: Report of a Case and Review of the Literature

Case Reports in Transplantation, 2011
Renal transplantation increases the probability of malignant tumors by about 2–4-fold overall with a much higher rate for renal epithelial malignancy.
Zhanyong Bing, John E. Tomaszewski
doaj   +1 more source

Targeting Lactate and Lactylation in Cancer Metabolism and Immunotherapy

Advanced Science, EarlyView.
Lactate, once deemed a metabolic waste, emerges as a central regulator of cancer progression. This review elucidates how lactate and its epigenetic derivative, protein lactylation, orchestrate tumor metabolism, immune suppression, and therapeutic resistance.
Jiajing Gong, Yuhang Xie, Zhijie Weng, Yongzhi Wu, Longjiang Li, Bo Li   +5 more
wiley   +1 more source

Surgical management for upper tract transitional cell carcinoma [PDF]

, 2008
This review is published as a Cochrane Review in the Cochrane Database of Systematic Reviews 2008, Issue 4. Cochrane Reviews are regularly updated as new evidence emerges and in response to comments and criticisms, and the Cochrane Database of Systematic
Cohen, Nicholas P., McClinton, Samuel, N'Dow, James M. O., Nabi, Ghulam, Rai, Bhavan Prasad, Shelley, Mike   +5 more
core   +3 more sources

The Cancer Genome Atlas Comprehensive Molecular Characterization of Renal Cell Carcinoma

Cell Reports, 2018
SUMMARY Renal cell carcinoma (RCC) is not a single disease, but several histologically defined cancers with different genetic drivers, clinical courses, and therapeutic responses.
C. Ricketts, Aguirre A. de Cubas, Huihui Fan, Christof C. Smith, M. Lang, Ed Reznik, R. Bowlby, E. Gibb, Rehan Akbani, R. Beroukhim, D. Bottaro, T. Choueiri, R. Gibbs, A. Godwin, S. Haake, A. Hakimi, E. Henske, J. Hsieh, T. Ho, R. Kanchi, B. Krishnan, David J. Kwaitkowski, Wembin Lui, M. Merino, G. Mills, J. Myers, M. Nickerson, V. Reuter, L. Schmidt, C. Shelley, Hui Shen, B. Shuch, S. Signoretti, R. Srinivasan, P. Tamboli, G. Thomas, B. Vincent, C. Vocke, D. Wheeler, Lixing Yang, William T. Kim, A. G. Robertson, P. Spellman, W. Rathmell, W. Linehan   +44 more
semanticscholar   +1 more source