Results 151 to 160 of about 5,991,856 (299)

TRIM2 downregulation in clear cell renal cell carcinoma affects cell proliferation, migration, and invasion and predicts poor patients’ survival

, 2018
Wen Xiao, Xuegang Wang, Tao Wang, Jinchun Xing Department of Urology, The First Affiliated Hospital of Xiamen University, Xiamen 361003, China Background and aim: Tripartite motif containing (TRIM) family protein has been involved in multiple ...
Xing J, Wang T, Xiao W, Wang X
core  

PTBP1‐Mediated Alternative Splicing of DNAJB6 Promotes Everolimus Resistance in Clear Cell Renal Cell Carcinoma via EIF4B/PKIB/AKT/mTOR Positive Feedback Loop

Advanced Science, EarlyView.
PTBP1‐mediated alternative splicing drives a pathogenic switch to the DNAJB6b isoform in everolimus‐resistant clear cell renal cell carcinoma. This splicing event programs a positive feedback loop including EIF4B/PKIB/AKT/mTOR, promoting aggressive therapy resistance.
Xiu‐wu Pan, Hong‐feng Zheng, Mu‐chen Li, Jia‐lin Zhou, Hang‐biao Zhang, Dong‐hao Lyu, Yi‐fan Tang, Tian‐yue Yang, Yi‐fan Liu, Zi‐chang Liu, Wen‐jie Ma, Yuan‐bo Zong, Jian‐gui Liu, Zi‐xuan Gong, Hao Zhang, Ke‐qin Dong, Wang Zhou, Jian‐qin Ye, Xin‐gang Cui   +18 more
wiley   +1 more source

A collision of two primary renal neoplasms: A rare case report. [PDF]

Urol Case Rep
Chaker K, Khadhar A, Mosbahi B, Limem A, Ammous A, Nouira Y.   +5 more
europepmc   +1 more source

guichengpeng1/WSI-based-deep-learning-classifier-in-papillary-renal-cell-carcinoma: WSI-based deep learning classifier in papillary renal cell carcinoma

<p>Deep learning for predicting recurrence in papillary renal cell carcinoma.</p> <p>The model was built around multiple instance learning and comprised a MobileNet V3 representation network, a Noisy-AND pooling function, and a fully ...
Chengpeng Gui, huangkb1005
core   +1 more source

Advances in Aptamer Drug Delivery Systems for Treatment of Glioblastoma

Advanced Science, EarlyView.
Aptamers have remarkable recognition capacity which is suitable for assisting drug delivery for GB. This review demonstrates that aptamers have great potential as targeted therapeutic carriers, conjugated to various therapeutic carriers, using a range of conjugation strategies and chemistries.
Alexandra R. Paul, Alexandra Moreno Mitchell, Dean O'Neil, Yutong Luo, Khuloud T. Al‐Jamal   +4 more
wiley   +1 more source

Genetic Heterogeneity in Renal Cell Carcinoma: A Case of Concurrent Clear Cell and Papillary Renal Carcinomas. [PDF]

Case Rep Urol
Kerckhofs A, Dautricourt S, van Kempen L, De Wachter S, Ramadhan A.   +4 more
europepmc   +1 more source

Renal cell carcinoma: links and risks

, 2016
Reena Kabaria, Zachary Klaassen, Martha K Terris Department of Surgery, Section of Urology, Augusta University, Augusta, GA, USA Abstract: This review provides an overview of the incidence of renal cell carcinoma (RCC) and a summary of the most commonly
Terris MK, Klaassen Z, Kabaria R
core  

Isocyanate‐Modified Melatplatin(IV) Enhances Antitumor Efficacy via TCF4/COL6A3‐Mediated Extracellular Matrix Remodeling and cGAS‐STING Pathway Activation in Bladder Cancer

Advanced Science, EarlyView.
A series of melatonin‐conjugated platinum(IV) prodrugs was functionalized with isocyanate chains (compounds 5‒12). MP‐12C (compound 11) was identified as the lead candidate, with optimal potency and safety. MP‐12C exhibited greater efficacy than cisplatin by increasing intracellular uptake, reshaping the extracellular matrix, activating the cGAS‐STING ...
Linhui Wang, Xiaomeng Liu, Tao Zhu, Zirun Su, Ruiping Liu, Zhe Li, Kaixuan Du, Kaipeng Jia, Chong Fu, Yuda Lin, Zihan Xue, Zhe Zhang, Chong Shen, Yunkai Qie, Zhouliang Wu, Zhiheng Liu, Kangkang Liu, Jingyuan Xu, Hailong Hu   +18 more
wiley   +1 more source

Proliferative behaviour and cytogenetic changes in human renal-cell carcinoma [PDF]

, 1991
Werner, M., Stief, Christian Georg, Riese, W. de, Azpodien, J., Kirchner, H., Jonas, Udo, Allhoff, E. P., Djamilian, Mohamad H., Schlick, R. W.   +8 more
core   +1 more source

A Gut‐Brain Axis Underlying Succinate‐Associated Compulsive‐Like Behavior

Advanced Science, EarlyView.
Gut‐derived succinate is associated with an excitatory‐inhibitory imbalance in dmPFC glutamatergic neurons, involving microglial SUCNR1 activation and vagal afferent signaling via upregulated gut 5‐HT4 receptors along the DVC‐CeA‐dmPFC circuit, changes that are linked to excessive compulsive‐like behavior.
Yi Li, Ying‐Dan Zhang, Wei Wang, Xin‐Yi Wu, Di Li, Xin Gong, Fei Tian, Meng‐Yu Dai, Jian Gao, Zi‐Feng Zheng, Zi‐Yang Bi, Dong‐Dong Shi, Zhen Wang   +12 more
wiley   +1 more source