Results 71 to 80 of about 357,374 (264)

MiR-122 promotes renal cancer cell proliferation by targeting Sprouty2

Tumor Biology, 2017
MicroRNAs are short non-coding RNAs, which have been implicated in several biological processes. Aberrant expression of the microRNA miR-122 has frequently been reported in malignant cancers.
Zijie Wang, Chao Qin, Jing Zhang, Zhijian Han, Jun Tao, Qiang Cao, Wanli Zhou, Zhen Xu, Chunchun Zhao, Ruoyun Tan, Min Gu   +10 more
doaj   +1 more source

Co-insidental, Ipsilateral Renal Cell Carcinoma and Urothelial Carcinoma of Ureter: A Rare Case

, 2016
Renal cell carcinoma and urothelial carcinoma of the upper urinary tract are not rare urological malignancies, however, in a patient with renal cell carcinoma and urothelial carcinoma seen simultaneously in the same kidney is a rare event.
Tarık Yonguç, Özgü Aydoğdu, Volkan Şen, İbrahim Halil Bozkurt, Tansu Değirmenci, İbrahim Küçüktürkmen   +5 more
core   +1 more source

Clear cell renal cell carcinoma and papillary renal cell carcinoma: differentiation of distinct histological types with multiphase CT [PDF]

, 2013
PURPOSEConventional clear cell renal cell carcinoma (ccRCC) and papillary renal cell carcinoma (pRCC) have different behavioral characteristics and clinical management strategies (nephrectomy vs. nephron-sparing surgery).
David Laszlo Tarnoki, Peter Nyirady, Bence Fejer, Attila Szendroi, A. Marcell Szasz, Dora Kekesi, Viktor Berczi, Pal Bata, Janos Gyebnar, Adam Domonkos Tarnoki, Kinga Karlinger   +10 more
core   +1 more source

Super‐Resolution Ultrasound Based Cell Tracking With Polymeric Nanobubbles

Advanced Materials, EarlyView.
This study presents a super‐resolution ultrasound platform for tracking cells in vivo. Biocompatible polymeric nanobubbles are used as highly echogenic intracellular labels. Following the injection of cells and microbubbles, ultrasound localization microscopy (ULM) can dynamically match the microvascular architecture and individual cell trajectories ...
Junlin Chen, Xiaoyu Wang, Jilin Fan, Bi Wang, Hanghang Fang, Yurui Wang, Hao Cui, Mohammad Roufarshbaf, Ekaterina Savina, Alexandra Valeske, Quim Peña, Yang Shi, Andreas Herrmann, Twan Lammers, Mathias Hornef, Roman Barmin, Thomas Lisson, Georg Schmitz, Anne Rix, Fabian Kiessling   +19 more
wiley   +1 more source

Ovarian metastases from renal cell carcinoma: A report of two cases

Fujita Medical Journal
Renal cell carcinoma is a malignant tumor that is prone to distant metastasis, primarily developing in the lungs, bones, lymph nodes, liver, and brain.
Junichi Takagi, Ryoko Ichikawa, Kyohei Takada, Akiko Ohwaki, Mayuko Ito, Yutaka Torii, Hiroyuki Nomura, Haruki Nishizawa   +7 more
doaj   +1 more source

ПРАКТИЧЕСКИЕ РЕКОМЕНДАЦИИ ПО ПРЕДОТВРАЩЕНИЮ И КОРРЕКЦИИ ПОБОЧНЫХ ЭФФЕКТОВ СУНИТИНИБА

, 2010
At present Sunitinib is the drug of choice in the treatment of metastatic renal cell carcinoma. In some cases complications due to the use of the drug make it to be unreasonably discontinued, which potentially affects the results of therapy.
S. L. Gutorov, С. Л. Гуторов, Е. И. Борисова, E. I. Borisova   +3 more
core   +1 more source

TRMT6‐Mediated m1A Modification of CDK9 mRNA Is a Dual‐Pronged Pathogenic Driver for HBV‐Related Hepatocellular Carcinoma

Advanced Science, EarlyView.
TRMT6‐mediated m1A modification in CDK9 mRNA enhances its mRNA stability and translation efficiency, thereby increasing the protein levels of CDK9. Upregulated CDK9 promotes the progression of HCC by elevating the levels of oncogenic factors including p‐STAT3, MCL1, and BCL‐2. On the other hand, CDK9 phosphorylates TARDBP at Ser254 to activate HBV core
Rui Zhang, Dandan Zong, Rui Liu, Yubo Wang, Qingqing Gu, Yao Yao, Wenfang Zheng, Mengmeng Yuan, Simeng Wang, Rongrong Cui, Daxu Li, Siwen Dang, Peng Hou   +12 more
wiley   +1 more source

Mitochondria and Neuromast Tagging With Fluorescent Gallium‐Triapine Analogues: In Cellulo MP FLIM and Zebrafish Live Imaging

Advanced Science, EarlyView.
Fluorescent BODIPY‐conjugated thiosemicarbazone ligands and their Ga(III), In(III), and Fe(III) complexes, inspired by Triapine, are developed as theranostic agents. Multiphoton FLIM and confocal microscopy in cancer cells and zebrafish reveal real‐time uptake, mitochondrial localisation, and whilst spectroscopic assays indicated preserved complex ...
Megan J. Green, Michael W. Jones, Merissa Saleem, Haobo Ge, Melita Tvardauskaite, Julia Dudzic, Fernando Cortezon‐Tamarit, Rory L. Arrowsmith, Charareh Pourzand, Gabriele Kociock‐Kohn, Nicholas H. Rees, Jonathan R. Dilworth, Stephen Faulkner, Stanley W. Botchway, David Gurevich, Sofia I. Pascu   +15 more
wiley   +1 more source

DAB2IP Plays Important Clinical Significance and Correlates With Immune Infiltration in Renal Cell Carcinoma

Technology in Cancer Research & Treatment, 2020
Background: Disabled homolog 2-interacting protein is a new member of the Ras GTPase superfamily involved in the regulation of cell proliferation, apoptosis, and metastasis.
Haoyuan Cao MM, Jiandong Zhang MD, Wei Wang MD   +2 more
doaj   +1 more source

Tumor‐Derived Alpha‐1 Antitrypsin Promotes Liver Metastasis of Colorectal Cancer Through the Neutrophil Extracellular Traps–CCDC25 Pathway

Advanced Science, EarlyView.
ABSTRACT Liver metastasis is a leading cause of mortality in colorectal cancer (CRC), where the inflammatory tumor microenvironment, specifically neutrophil infiltration, significantly promotes metastatic colonization. This study reveals a pro‐metastatic role for alpha‐1 antitrypsin (A1AT) in CRC liver metastasis via a dual mechanism involving ...
Qian Fei, Chunning Li, Lei Zhan, Xiaoyan Li, Yan Hui, Yue Jin, Jing Zhang, Lu Yang, Xin Sun, Xiaoxi Li, Qian Dong, Jingdong Zhang   +11 more
wiley   +1 more source