Results 91 to 100 of about 5,029,915 (387)

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira, Anna Skwarska, Karolina Chwialkowska, Agnieszka Ostrowska, Gabriela Sokolowska, Anna Zeller, Anna Erol, Andrzej Eljaszewicz, Bartosz Hanczaruk, Anna Michalska‐Falkowska, Agnieszka Tarasik, Joanna Reszec‐Gielazyn, Pawel Knapp, Marcin Moniuszko, Adam Kretowski   +14 more
wiley   +1 more source

Effect and safety of immunotherapy among elder patients (age ≥ 65) with recurrent or metastatic nasopharyngeal carcinoma

BMC Cancer
Background The use of immune checkpoint inhibitors (ICIs) combined with chemotherapy constitutes the first-line treatment for recurrent or metastatic nasopharyngeal carcinoma (RM-NPC).
Rui-Ling Xie, Wu-Lin Cai, Yan-Feng Ouyang, Ye-Hao Zou, Rui Sun   +4 more
doaj   +1 more source

Limited recurrence distance of glioblastoma under modern radiotherapy era

BMC Cancer, 2021
Background The optimal treatment volume for Glioblastoma multiforme (GBM) is still a subject of debate worldwide. The current study was aimed to determine the distances between recurring tumors and the edge of primary lesions, and thereby provide ...
Ziwei Tu, Huifen Xiong, Yang Qiu, Guoqing Li, Li Wang, Shiyi Peng   +5 more
doaj   +1 more source

High Interleukin-6, Low Cd4+ and Cd8+ T-lymphocytes Expressions as Risk Factors of Cervical Carsinoma Infected by Human Papilloma Virus Type-52 [PDF]

, 2013
In Indonesia cervical carcinoma is the most common cancer in women and one of the leading cause of mortality. High risk human papillomavirus (HPV) is the major risk factor of cervical cancer.
Alit-Artha, A. I. (and), Joewarini, E. (E), Mahendra-Dewi, I. G. (I), Suwiyoga, I. K. (I)   +3 more
core  

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

Molecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian, Sriraam Sivachandran, Melissa Galati, Brandon Ramchatesingh, Hibo Rijal, Johnny Hanna, Elena Netchiporouk, May Chergui, Margaret Redpath, Samy Abou Setah, Ivan V. Litvinov   +10 more
wiley   +1 more source

Predictive value of nasopharyngeal microbiota for necrosis after re-irradiation in recurrent nasopharyngeal carcinoma

BMC Cancer
Background Post-radiation nasopharyngeal necrosis (PRNN) is a severe complication following re-irradiation in patients with recurrent nasopharyngeal carcinoma (NPC).
Kai Wen, Ze-Rong Huang, Yong-Long Liu, Wen-Bin Wu, Zi-Han Qin, Yan-Feng Ouyang, Xiong Zou, Rui You, You-Ping Liu, Ming-Yuan Chen, Yi-Jun Hua   +10 more
doaj   +1 more source

Nomogram Predicting the Benefits of Adding Concurrent Chemotherapy to Intensity-Modulated Radiotherapy After Induction Chemotherapy in Stages II–IVb Nasopharyngeal Carcinoma

Frontiers in Oncology, 2020
BackgroundTo compare the efficacy of induction chemotherapy plus concurrent chemoradiotherapy (IC+CCRT) versus induction chemotherapy plus radiotherapy (IC+RT) in patients with locoregionally advanced nasopharyngeal carcinoma (NPC).Patients and ...
Sai-Lan Liu, Sai-Lan Liu, Xue-Song Sun, Xue-Song Sun, Zi-Jian Lu, Zi-Jian Lu, Qiu-Yan Chen, Qiu-Yan Chen, Huan-Xin Lin, Huan-Xin Lin, Lin-Quan Tang, Lin-Quan Tang, Jin-Xin Bei, Ling Guo, Ling Guo, Hai-Qiang Mai, Hai-Qiang Mai   +16 more
doaj   +1 more source

Invasive Carcinoma

, 2017
This chapter illustrates the main form of breast cancer setting the basis of the diagnosis of malignancy on FNAC and providing some hints to direct cytological interpretation towards one or the other specific type of ...
Pinamonti M., Zanconati F.
openaire   +3 more sources

Cabozantinib in Patients with Advanced and Progressing Hepatocellular Carcinoma

New England Journal of Medicine, 2018
BACKGROUND Cabozantinib inhibits tyrosine kinases, including vascular endothelial growth factor receptors 1, 2, and 3, MET, and AXL, which are implicated in the progression of hepatocellular carcinoma and the development of resistance to sorafenib, the ...
G. Abou-Alfa, T. Meyer, A. Cheng, A. El-Khoueiry, L. Rimassa, B. Ryoo, I. Çiçin, P. Merle, Yen-Chang Chen, Joong-Won Park, J. Blanc, L. Bolondi, H. Klümpen, S. Chan, V. Zagonel, T. Pressiani, M. Ryu, A. Venook, C. Hessel, A. Borgman-Hagey, G. Schwab, R. Kelley   +21 more
semanticscholar   +1 more source

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

Molecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy, Samuel Hartzler, Paula A. Vargas Carranza, Shyaman Jayasundara, Madison E. Yates, Nimod D. Janson, Bozhi Liu, Annaleigh Benton, Majid Kazemian, Jason A. Hanna   +9 more
wiley   +1 more source