Nivolumab versus Everolimus in Advanced Renal-Cell Carcinoma.
R. Motzer +26 more
semanticscholar +1 more source
A bioinformatics screen identifies TCF19 as an aggressiveness‐sustaining gene in prostate cancer
Gene expression meta‐analysis in multiple prostate cancer patient cohorts identifies Transcription factor 19 (TCF19) as an aggressiveness‐sustaining gene with prognostic potential. TCF19 is a gene repressed by androgen signaling that sustains core cancer‐related processes such as vascular permeability or tumor growth and metastasis.
Amaia Ercilla +15 more
wiley +1 more source
Papillary carcinoma of the bladder in mice, obtained after peroral administration of tobacco tar [PDF]
Lars R. Holsti, Pentti Ermala
openalex +1 more source
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
Nuclear mass and allied phenomena in normal exocervical mucosa, squamous metaplasia, atypical hyperplasia, intraepithelial carcinoma, and invasive squamous cell carcinoma of the uterine cervix [PDF]
Alvan G. Foraker, James W. Reagan
openalex +1 more source
Nivolumab plus Ipilimumab versus Sunitinib in Advanced Renal‐Cell Carcinoma
R. Motzer +31 more
semanticscholar +1 more source
Using multi‐omic characterization, we aimed to identify key regulators specific to squamous cell lung carcinoma (SqCC). SqCC‐specific differentially expressed genes were integrated with metabolics data. High expression of the creatine transporter SLC6A8, along with elevated creatine levels, appeared to be a distinct metabolic feature of SqCC.
Johan Staaf +10 more
wiley +1 more source
Adrenal-cortical carcinoma and melanocarcinoma in a 5-year-old negro child [PDF]
John B. Poore +2 more
openalex +1 more source
Durvalumab: an investigational anti-PD-L1 monoclonal antibody for the treatment of urothelial carcinoma. [PDF]
Our expanding knowledge of immunotherapy for solid tumors has led to an explosion of clinical trials aimed at urothelial carcinoma. The primary strategy is centered on unleashing the immune system by releasing the inhibitory signals propagated by ...
Chamie, Karim +5 more
core +1 more source
A global view of hepatocellular carcinoma: trends, risk, prevention and management
J. D. Yang +5 more
semanticscholar +1 more source

