Results 331 to 340 of about 4,947,478 (390)

Lithium‐Charged Gold Nanoparticles: A New Powerful Tool for Lithium Delivery and Modulation of Glycogen Synthase Kinase 3 Activity

open access: yesAdvanced Materials, EarlyView.
This study introduces glutathione‐stabilized gold nanoparticles for targeted lithium delivery (LiG‐AuNPs), enabling the controlled modulation of Glycogen Synthase Kinase‐3 (GSK‐3β). These non‐toxic, 2‐nm particles release lithium intracellularly, effectively inhibiting GSK‐3β in the brain without significant plasma lithium alterations.
Antonio Buonerba   +20 more
wiley   +1 more source

Cancer Cells Traverse Faster in Confined Space by Modifying Vimentin filaments With Nuclear Deformation and Promoting the Growth of Desired Tumor Spheroids

open access: yesAdvanced Materials Interfaces, EarlyView.
This study demonstrates how the Vimentin intermediate (VIM) filaments distribution/density regulates the attainment of different migration modes through cytoskeleton rearrangement and controls the nuclear morphology in migrating cells under physical confinement, which facilitates the faster traversing of those cells and the growth of post‐migration ...
Md Kowsar Alam   +4 more
wiley   +1 more source

Radical Retention and Functional Stability of Plasma‐Polymerized Nanoparticles for Long‐Term Biofunctionalization

open access: yesAdvanced Materials Interfaces, EarlyView.
Plasma polymerized nanoparticles (PPNs) offer a solvent‐free route to functional nanocarriers with long‐lived radicals. This study establishes design principles for long‐term storage of PPNs, demonstrating that dry‐phase storage retains radical content, covalent reactivity, and bioactivity over extended periods. These findings advance the translational
Elmer Austria Jr.   +11 more
wiley   +1 more source

Microneedles From Shape‐Preserving Crosslinked Poly(Vinyl Alcohol) Hydrogels: Minimising Interference in Transdermal Proteomics

open access: yesAdvanced Materials Technologies, EarlyView.
Hydrogel‐forming microneedle patches are developed using shape‐preserving PVA‐PVP hydrogels, with and without chitosan, for minimally invasive transdermal protein biomarker sampling. The optimised patches enable efficient interstitial fluid uptake and proteomic analysis, while minimising interference.
Achmad Himawan   +12 more
wiley   +1 more source

Can PSMA-Targeting Radiopharmaceuticals Be Useful for Detecting Brain Metastasis of Various Tumors Using Positron Emission Tomography? [PDF]

open access: yesCancers (Basel)
Arslan E   +8 more
europepmc   +1 more source

Applications of QSPR and Machine Learning in Molecular Photonics

open access: yesAdvanced Optical Materials, EarlyView.
Quantitative structureproperty relationships (QSPR) and machine learning (ML) are transforming photochemistry by enabling pre‐synthetic screening of photoactive molecules. This review outlines advances in data‐driven discovery of optical materials and functional dyes, identifies effective descriptors and models for photophysical processes, and provides
Andrey A. Buglak   +2 more
wiley   +1 more source

Home - About - Disclaimer - Privacy