Results 61 to 70 of about 5,029,915 (387)

Primary Signet-Ring Carcinoma (Linitus Plastica) of the Colorectum presenting as Subacute Intestinal Obstruction [PDF]

open access: yes, 2012
Primary Signet-ring cell carcinoma (Linitus Plastica) of the colon and rectum is a rare form of adenocarcinoma of the large intestine and has been reported to have an extremely poor prognosis. We report a case of Primary Signet-ring cell carcinoma of the
Jagtap, SS   +4 more
core  

DACH1 suppresses breast cancer as a negative regulator of CD44. [PDF]

open access: yes, 2017
Dachshund homolog 1 (DACH1), a key cell fate determination factor, contributes to tumorigenesis, invasion, metastasis of human breast neoplasm. However, the exact molecular mechanisms for the anti-tumor roles of DACH1 in breast carcinoma are still lack ...
Kuang, Dong   +6 more
core   +2 more sources

Unique case of inverted papilloma of septum with nasopharyngeal carcinoma:Is it a metachronous tumour? [PDF]

open access: yes, 2020
Inverted papilloma is a rare and benign tumour. It affects the nasal cavity and paranasal sinuses, has a high rate of recurrence and is associated with malignant transformation.
Ferguson, Aaron S. J.   +4 more
core   +3 more sources

Integrated Genomic Analyses of Ovarian Carcinoma

open access: yesNature, 2011
A catalogue of molecular aberrations that cause ovarian cancer is critical for developing and deploying therapies that will improve patients’ lives. The Cancer Genome Atlas project has analysed messenger RNA expression, microRNA expression, promoter ...
D. Bell   +261 more
semanticscholar   +1 more source

Thyroid Carcinoma, Version 2.2022, NCCN Clinical Practice Guidelines in Oncology.

open access: yesThe Journal of the National Comprehensive Cancer Network, 2022
Differentiated thyroid carcinomas is associated with an excellent prognosis. The treatment of choice for differentiated thyroid carcinoma is surgery, followed by radioactive iodine ablation (iodine-131) in select patients and thyroxine therapy in most ...
R. Haddad   +35 more
semanticscholar   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Harnessing the machine learning and nomogram models: elevating prognostication in nonmetastatic gastric cancer with “double invasion” for personalized patient care

open access: yesEuropean Journal of Medical Research
Objective To develop and validate a machine learning framework combined with a nomogram for predicting recurrence after radical gastrectomy in patients with vascular and neural invasion.
Zhenwen Hao   +4 more
doaj   +1 more source

AHNAK and inflammatory markers predict poor survival in laryngeal carcinoma. [PDF]

open access: yes, 2012
AHNAK/Desmoyokin is a giant protein which has been recently linked to reorganization of the actin cytoskeleton, cellular migration and invasion. Here, we investigated the role of AHNAK in the pathophysiology of larynx carcinoma-one of the major subtypes ...
Bankfalvi, Agnes   +5 more
core   +2 more sources

Targeting EZH2 reverses thyroid cell dedifferentiation and enhances iodide uptake in anaplastic thyroid cancer

open access: yesFEBS Letters, EarlyView.
Anaplastic thyroid cancer (ATC) lacks iodide uptake ability due to MAPK activation increasing the expression of the histone methyltransferase EZH2, which represses thyroid differentiation genes (TDGs) such as the sodium iodide symporter (NIS). Dual inhibition of MAPK (U0126) and EZH2 (EPZ6438/Tazemetostat) reverses this mechanism, thus restoring TDG ...
Diego Claro de Mello   +6 more
wiley   +1 more source

Outcomes of patients in nasopharyngeal adenoid cystic carcinoma in the IMRT era: a single-center experience

open access: yesBMC Cancer
Objective Nasopharyngeal adenoid cystic carcinoma (NACC) is a rare malignancy with special biological features. Controversies exist regarding the treatment approach and prognostic factors in the IMRT era.
Wen-Bin Wu   +12 more
doaj   +1 more source

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