Results 81 to 90 of about 644 (187)
Exceptional Response of HER2‐Positive Breast Cancer to Osimertinib: A Case Report
An 83‐year‐old woman with synchronous EGFR L858R‐mutated lung adenocarcinoma and HER2‐positive breast cancer received osimertinib monotherapy for lung cancer without breast‐directed therapy. The breast tumor showed durable radiological and metabolic regression, with a Grade 3 therapeutic effect and HER2 amplification confirmed at postmortem biopsy ...
Hirotoshi Yasui +10 more
wiley +1 more source
Mitochondria Dictate Progressive Versus Bimodal Aging of the Mammary Gland
Breast cancer shows a bimodal age distribution with a peak at 45 and higher peak at 65. Using mice with different mitochondrial genomes, we show progressive and bimodal patterns of aging of the mammary gland with distinct pro‐tumorigenic age windows. This finding may shed light on the bimodal distribution in humans.
Edmund Charles Jenkins +6 more
wiley +1 more source
RASD2 Drives Renal Clear Cell Carcinoma Progression via RAF1 (Ser338) Phosphorylation
RASD2 drives clear cell renal cell carcinoma (ccRCC) progression by physically interacting with RAF1 to induce its Ser338 phosphorylation, which subsequently activates the P38/ERK–MAPK signaling pathway to promote malignant tumor phenotypes and poor prognosis.
Jingxuan Yu +10 more
wiley +1 more source
Estudo descritivo dos casos de câncer de mama em Goiânia, entre 1989 e 2003
OBJETIVO: Descrever os casos de câncer de mama nas mulheres residentes em Goiânia no período 1989-2003. MÉTODOS: Estudo retrospectivo, descritivo, que incluiu todos os casos de câncer de mama ocorridos nas moradoras de Goiânia, identificados pelo ...
Rodrigo Disconzi Nunes +5 more
doaj +1 more source
Secretory Carcinoma Mimicking a Mucocele: Case Report and Literature Update
ABSTRACT Aim Secretory carcinoma (SC), also known as mammary analogue secretory carcinoma, is a rare malignant neoplasm of the salivary glands, named for its histological and molecular resemblance to mammary secretory carcinoma. The aim of this study is to present a new case of SC occurring in the lower lip, initially diagnosed as a mucocele, and to ...
Débora Frota Colares +5 more
wiley +1 more source
Background: Contagious ecthyma (Orf) is a highly contagious, economically significant disease affecting sheep, goats and wild small ruminants, caused by the resilient Orf virus (ORFV). It produces thick, crusted lesions around the mouth and nostrils, especially in animals aged 3–4 months, sometimes causing near 100% mortality in immunocompromised young
Emine Nur Dincer, Ozlem Ozmen
wiley +1 more source
OBJETIVO: presentar los resultados de nuestra experiencia en el tratamiento de pacientes con cáncer de mama estadio precoz, tratadas con Radioterapia Ultrahipofraccionada (RTUF) en el servicio Dr. Enrique Gutiérrez CMDLT.
Carmen Sanchez, Sara Ott, Rosario Reyes
doaj
Introducción: El objetivo de este estudio consistió en analizar la subestimación del carcinoma ductal invasivo (CDI), en pacientes con diagnóstico preoperatorio de carcinoma ductal in situ (CDIS) e identificar los factores asociados con el riesgo de infradiagnóstico.
openaire +1 more source
Fundamento: Cuba, como otros países, investiga para dilucidar los mecanismos de defensa antitumoral y la obtención de productos inmunomoduladores con potencial terapéutico y antitumoral. Objetivo: Caracterizar los linfocitos T que infiltran estos tumores,
Jenny Yorllana Luna Esquivel +3 more
doaj
Breast Cancer. A Characterization in the Decade from 1996-2005.
Background: Breast Cancer constitutes a health problem in Cuba due to it is the first cause and localization of death for malignant tumors in females.
Lidia Torres Ajá +5 more
doaj +2 more sources

