Results 91 to 100 of about 47,297 (213)
Pathological assessment of post‐neoadjuvant treatment (NAT) breast specimens uses more laboratory resources compared with non‐NAT cases. The highest resource utilization (specimen resampling, number of tissue blocks submitted, pathologist review) occurred when the tumour bed is not grossly identifiable.
Angela Cheng +4 more
wiley +1 more source
Zebrafish provide a high‐throughput, optically transparent platform for cancer and drug screening. Their ~80% genetic homology, xenograft compatibility, and transgenic strains enable targeted photosensitizer screening, real‐time ROS and tumor imaging, and mechanistic assays, while fish embryo acute toxicity (FET) and in vitro tests streamline toxicity ...
Ethan Wilson +5 more
wiley +1 more source
ABSTRACT This study presents a comprehensive transcriptomic analysis of 128 canine mammary tumours (CMTs), aiming to characterize their molecular landscape. Differential gene expression analysis (DGE), gene set enrichment analysis (GSEA) and clustering based on the human PAM50 gene panel were applied to explore molecular differences between the ...
Ingrid Marie Moberg +8 more
wiley +1 more source
ABSTRACT Background and Aims This study aimed to assess the prognosis and outcomes of additional treatment for residual adenocarcinoma and adenoma following endoscopic papillectomy (EP) for ampullary tumors. Methods Of 191 patients who underwent EP, 43 with adenocarcinoma or adenoma and either positive or unknown pathological margins were included ...
Yusuke Kurita +24 more
wiley +1 more source
An Update on Early‐Onset Breast Cancer: Incidence, Risk Factors, Genetic Testing, and Treatment
ABSTRACT Early‐onset breast cancer presents in patients typically under the age of 40, while very early‐onset breast cancer is usually viewed as breast cancer occurring before the age of 35. Early‐onset breast cancer demonstrates specific molecular properties and has worse outcomes compared to its late‐onset breast cancer counterpart.
Leila Jahangiri
wiley +1 more source
Neoadjuvant endocrine therapy (NET) can help prevent metastases and improve survival in patients with hormone receptor‐positive (HR+) breast cancer. Identifying which HR+ patients will benefit from NET, however, remains challenging. Here, in a patient cohort in the Netherlands, the authors evaluated tumor‐stroma ratio (TSR) and magnetic resonance ...
Layla Andour +8 more
wiley +1 more source
ABSTRACT Cervical metastases from breast carcinoma should be considered in the differential diagnosis of uterine lesions in patients with prior breast cancer. Re‐biopsy is essential to detect receptor discordance (ER/PR up to 29%) and guide therapy. GCDFP‐15, mammaglobin, and GATA3 confirm mammary origin.
Mario Assenza +3 more
wiley +1 more source
ABSTRACT Background Malignant effusions in breast cancer are a minimally invasive source for molecular profiling. Effusion‐derived cytology specimens, cell blocks (CB) and post‐ThinPrep PreservCyt (PTPC) supernatant, are reliable sources for molecular testing but differ in DNA concentration and turnaround time (TAT).
Harpreet Virk +5 more
wiley +1 more source
Expert Discussion: Ductal Carcinoma in situ [PDF]
Peter Dall +6 more
openaire +2 more sources

