Results 121 to 130 of about 28,817 (265)

Bidirectional crusher gradient method to estimate the labeling efficiency of pseudo‐continuous arterial spin labeling MRI in mice

Magnetic Resonance in Medicine, Volume 95, Issue 2, Page 912-926, February 2026.
Abstract Purpose To develop an experimental method for measuring the labeling efficiency of pseudo‐continuous arterial spin labeling (pCASL) MRI in mice. Methods We propose a method using bidirectional crusher gradients to modulate vascular signals in the azygos pericallosal artery (azPA) of the mouse brain, applied with and without pCASL labeling. The
Xiuli Yang, Yuguo Li, Adnan Bibic, Maria Guadalupe Mora Alvarez, Hanzhang Lu, Zhiliang Wei   +5 more
wiley   +1 more source

Course of Pregnancy in a Woman With Familial Chylomicronemia Syndrome Treated With Plozasiran, a Small Interfering RNA Against ApoC3

JIMD Reports, Volume 67, Issue 1, January 2026.
ABSTRACT Persistent chylomicronemia is associated with severe hypertriglyceridemia (sHTG) and plasma triglycerides (TG) levels sustainably > 10 mmol/L (880 mg/dL) despite lipid lowering therapies. The main risk of persistent chylomicronemia is acute pancreatitis (AP). During the second and third trimester of pregnancy, TG levels significantly increase,
Miriam Larouche, Diane Brisson, Nathalie Roy, Claudy Grenon, Paul Poirier, Ma'an Muhsin, Daniel Gaudet   +6 more
wiley   +1 more source

Comparison of cardiac diffusion MRI using multiple prospective respiratory motion correction techniques

Magnetic Resonance in Medicine, Volume 95, Issue 1, Page 442-456, January 2026.
Abstract Purpose A novel prospective motion correction control system with slice tracking (MNav‐CoS) was compared with three other prospective respiratory motion correction techniques in performing free‐breathing cardiovascular diffusion tensor imaging (cDTI) acquisitions. Methods Ten healthy volunteers underwent cDTI using an M2SE sequence.
Stephen Jermy, Aaron Hess, Zakariye Ashkir, Betty Raman, Ian Burger, Francesca Little, Ntobeko Ntusi, Ernesta Meintjes, Elizabeth M. Tunnicliffe   +8 more
wiley   +1 more source

Clinical Utility of Serum Neurofilament Light Chain in Peripheral Neuropathy

Muscle &Nerve, Volume 73, Issue 1, Page 86-92, January 2026.
ABSTRACT Introductions/Aims The clinical utility of serum neurofilament light chain (sNfL) in the evaluation and management of peripheral neuropathy (PN) remains poorly defined. This study aimed to evaluate the utility of sNfL for diagnosing PN, assessing disease activity, and monitoring treatment response using a commercially available assay.
Chafic Karam
wiley   +1 more source

Cholesterol in mRNA‐Lipid Nanoparticles can be Replaced with the Synthetic Mycobacterial Monomycoloyl Glycerol Analogue MMG‐1

Advanced Functional Materials, Volume 35, Issue 51, December 16, 2025.
This study demonstrates that cholesterol in messenger RNA‐lipid nanoparticles (mRNA‐LNPs) can be completely replaced with an immunopotentiating lipid, i.e., a synthetic analogue of the C‐type lectin receptor agonist monomycoloyl glycerol (MMG‐1), without compromising physicochemical properties, in vivo transfection efficiency, and immunogenicity of the
Abhijeet G. Lokras, Saahil S. Baghel, Rune F. Jensen, Aneesh Thakur, Henrik Franzyk, Oskar Thofte, Marco Herrera‐Barrera, Madeleine Landry, Melike Ongun, Ahmad Tami, Marlene P. Thanthrige, Eva Callens, Corinne Beinat, Thomas Rades, Søren R. Paludan, Kristian Riesbeck, Ida Rosenkrands, Dennis Christensen, Gabriel K. Pedersen, Camilla Foged   +19 more
wiley   +1 more source

542 USE OF ANGIOTENSIN RECEPTOR/NEPRYLISIN INHIBITORS (ARNI) IN WILD TYPE TTR CARDIAC AMYLOIDOSIS (WTATTR) AND HEART FAILURE WITH REDUCED EJECTION FRACTION (HFREF) : IS IT WORTH A TRY? [PDF]

, 2022
Bianca Fowler, Antonella Vincenzi, Paolo Massa, Didi Massabo, Eleonora Lo Vullo, Maddalena Lettino   +5 more
openalex   +1 more source

Myocardial sympathetic distal axon loss in subjects with Lewy pathology: an artificial intelligence‐based histopathological analysis

Alzheimer's &Dementia, Volume 21, Issue S7, December 2025.
Abstract Background Cardiac manifestations, including arrhythmias and sudden deaths, are associated with Lewy body disease (LBD), but studies addressing the underlying histopathological mechanisms at the myocardial level are sparse. Increasing evidence supports the existence of body‐first and brain‐first subtypes of LBD, whose effects on cardiac ...
Ville Kivistö, Benjamin Englert, Jarno Tuimala, Eloise H Kok, Henri Puttonen, Anna Raunio, Pekka Karhunen, Maria K. Lehtinen, Per Borghammer, Ella Ahvenainen, Kia Colangelo, Sara Savola, Maarit Tanskanen, Karri Kaivola, Pentti J. Tienari, Darshan Kumar, Anders Paetau, Olli Tynninen, Mikko I. Mäyränpää, Tuomo Polvikoski, Liisa Myllykangas   +20 more
wiley   +1 more source

Extracardiac Accumulation of Technetium-99m-Pyrophosphate in Transthyretin Cardiac Amyloidosis

, 2021
Koji Takahashi, Daisuke Sasaki, Tomoki Sakaue, Daijiro Enomoto, Shigeki Uemura, Takafumi Okura, Shuntaro Ikeda, Daichi Yamamoto, Taizo Kono, Nobuhisa Yamamura   +9 more
openalex   +1 more source

Defining the Echocardiographic Phenotype of Patients With Cardiac Amyloidosis: A Systematic Review and Meta-Analysis [PDF]

, 2023
E. Hitchen, Jim Yip, A. Amarasekera, Jia Guo, Karima Addetia, Tuantuan Tan   +5 more
openalex   +1 more source

A Case of AL Amyloidosis With Hepatomegaly as the Main Clinical Manifestation

Clinical Case Reports, Volume 13, Issue 12, December 2025.
ABSTRACT Light chain (AL) amyloidosis presenting predominantly with hepatomegaly is a rare and frequently misdiagnosed condition. While clinical features are non‐specific, elevated ALP/GGT should raise suspicion. A liver biopsy remains the gold standard for diagnosis.
Shuchen Dong, Renjun Lv, Wei Wang, Guoling Gao, Mingfeng Zhao, Xingbin Ma   +5 more
wiley   +1 more source