Results 111 to 120 of about 720,196 (232)

Current perspectives on cardiac amyloidosis

open access: yes, 2012
Amyloidosis represents a group of diseases in which proteins undergo misfolding to form insoluble fibrils with subsequent tissue deposition. While almost all deposited amyloid fibers share a common nonbranched morphology, the affected end organs ...
Rodney H. Falk   +3 more
core   +1 more source

Cardiac Amyloidosis Versus Other Restrictive Cardiomyopathies: A Retrospective Analysis of Cardiovascular Outcomes and Arrhythmic Burden

open access: yesClinical Medicine Insights: Cardiology
Background: The arrhythmic burden and cardiovascular risks of cardiac amyloidosis compared with other types of restrictive cardiomyopathies (RCM), such as hemochromatosis and cardiac sarcoid, have not been well characterized in the literature.
Andrew Sagalov   +7 more
doaj   +1 more source

Senile cardiac amyloidosis: types, structural and functional characteristics, clinical forms, morphological diagnosis (literature review)

open access: yesИзвестия высших учебных заведений. Поволжский регион: Медицинские науки
Amyloidosis is a disease caused by the deposition of proteins with an unstable tertiary structure, which coagulate and accumulate in tissues as glycoprotein fibrils.
Nikita S. Averkin   +4 more
doaj   +1 more source

Educational Impact of Generalist–Specialist Collaborative Outpatient Training for Medical Students: A Qualitative Study

open access: yesJournal of General and Family Medicine, Volume 27, Issue 5, September 2026.
ABSTRACT Background Despite the recognized benefits of specialty outpatient training for medical students, such settings present educational challenges. To address these, our university incorporated generalist support into specialty outpatient education. The present study aimed to explore what medical students learned from this program.
Koki Nakamura   +4 more
wiley   +1 more source

From Single Cells to Diagnosis: Proteomics Technologies in the Multi‐Omics Landscape of Rare and Mitochondrial Diseases

open access: yesJournal of Inherited Metabolic Disease, Volume 49, Issue 5, September 2026.
Wetzel et al. outline how individual omics methods contribute to the diagnosis of patients with rare, and particularly mitochondrial diseases, with a focus on how spatial proteomics is joining this multi‐omics stack. ABSTRACT Proteomics by mass spectrometry has rapidly matured from a niche method into a standard tool.
Simon Wetzel   +2 more
wiley   +1 more source

Immunoglobulin Kappa Light Chain Produced by Cardiomyocytes and Participates in Maintaining Intercalated Disc Integrity

open access: yesMedComm, Volume 7, Issue 9, September 2026.
This study identifies Igκ expression in cardiomyocytes, with predominant localization at ICDs. Cardiomyocyte‐specific Igκ knockout induces cardiac dysfunction and ICDs structural disorganization. Mechanistically, Igκ stabilizes plectin to facilitate desmin‒actin network assembly and anchor desmin to DSP, which is critical for maintaining ICDs ...
Zhu Zhu   +12 more
wiley   +1 more source

Imaging cardiac innervation in amyloidosis [PDF]

open access: yes, 2019
Cardiac amyloidosis is a form of restrictive cardiomyopathy resulting in heart failure and potential risk on arrhythmia, due to amyloid infiltration of the nerve conduction system and the myocardial tissue.
Hazenberg, Bouke P C   +8 more
core   +3 more sources

Pulmonary Amyloidosis Diagnosed by Transbronchial Lung Biopsy: A Three‐Case Series With Diverse Radiological Manifestations

open access: yesRespirology Case Reports, Volume 14, Issue 9, September 2026.
Pulmonary amyloidosis presents with diverse radiological manifestations ranging from nodular lesions to diffuse interstitial abnormalities. Conventional forceps TBLB may serve different clinical roles according to disease presentation: distinguishing localized nodular amyloidosis from malignancy and providing an initial diagnostic clue to systemic ...
Masaki Tanaka   +9 more
wiley   +1 more source

Diagnostic Approach to Cardiac Amyloidosis [PDF]

open access: yes, 2014
Amyloidosis is a relatively rare disease that may be underdiagnosed and could affect the entire human body. Many organs may be affected, which could increase the morbidity and mortality.
Hirata, ken-ichi   +3 more
core  

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