Results 111 to 120 of about 720,196 (232)
Current perspectives on cardiac amyloidosis
Amyloidosis represents a group of diseases in which proteins undergo misfolding to form insoluble fibrils with subsequent tissue deposition. While almost all deposited amyloid fibers share a common nonbranched morphology, the affected end organs ...
Rodney H. Falk +3 more
core +1 more source
Background: The arrhythmic burden and cardiovascular risks of cardiac amyloidosis compared with other types of restrictive cardiomyopathies (RCM), such as hemochromatosis and cardiac sarcoid, have not been well characterized in the literature.
Andrew Sagalov +7 more
doaj +1 more source
Amyloidosis is a disease caused by the deposition of proteins with an unstable tertiary structure, which coagulate and accumulate in tissues as glycoprotein fibrils.
Nikita S. Averkin +4 more
doaj +1 more source
ABSTRACT Background Despite the recognized benefits of specialty outpatient training for medical students, such settings present educational challenges. To address these, our university incorporated generalist support into specialty outpatient education. The present study aimed to explore what medical students learned from this program.
Koki Nakamura +4 more
wiley +1 more source
Wetzel et al. outline how individual omics methods contribute to the diagnosis of patients with rare, and particularly mitochondrial diseases, with a focus on how spatial proteomics is joining this multi‐omics stack. ABSTRACT Proteomics by mass spectrometry has rapidly matured from a niche method into a standard tool.
Simon Wetzel +2 more
wiley +1 more source
This study identifies Igκ expression in cardiomyocytes, with predominant localization at ICDs. Cardiomyocyte‐specific Igκ knockout induces cardiac dysfunction and ICDs structural disorganization. Mechanistically, Igκ stabilizes plectin to facilitate desmin‒actin network assembly and anchor desmin to DSP, which is critical for maintaining ICDs ...
Zhu Zhu +12 more
wiley +1 more source
Imaging cardiac innervation in amyloidosis [PDF]
Cardiac amyloidosis is a form of restrictive cardiomyopathy resulting in heart failure and potential risk on arrhythmia, due to amyloid infiltration of the nerve conduction system and the myocardial tissue.
Hazenberg, Bouke P C +8 more
core +3 more sources
Pulmonary amyloidosis presents with diverse radiological manifestations ranging from nodular lesions to diffuse interstitial abnormalities. Conventional forceps TBLB may serve different clinical roles according to disease presentation: distinguishing localized nodular amyloidosis from malignancy and providing an initial diagnostic clue to systemic ...
Masaki Tanaka +9 more
wiley +1 more source
Diagnostic Approach to Cardiac Amyloidosis [PDF]
Amyloidosis is a relatively rare disease that may be underdiagnosed and could affect the entire human body. Many organs may be affected, which could increase the morbidity and mortality.
Hirata, ken-ichi +3 more
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