Results 121 to 130 of about 720,196 (232)
Experimental approaches to study cerebral amyloidosis in a transgenic mouse model of Alzheimer's disease [PDF]
Misfolding, aggregation and the accumulation of proteins in the brain are common characteristics of diverse age-related neurodegenerative diseases. Each of these neurodegenerative diseases is associated with abnormalities in the folding of a different
Meyer-Lühmann, Melanie
core +1 more source
Importance of tissue diagnosis in pulmonary amyloidosis, a rare albeit treatable cause of interstitial lung disease. ABSTRACT Pulmonary amyloidosis is a rare manifestation of amyloid deposition which can present as a rare albeit treatable cause of interstitial lung disease.
Kai Wen Hwang +3 more
wiley +1 more source
The identification of the glymphatic system (GS) and meningeal lymphatic vessels (mLVs) challenges the century‐old “immune‐privileged” dogma of the central nervous system (CNS), establishing a critical mechanistic link between impaired waste clearance (Aβ/tau) and the pathogenesis of Alzheimer's disease (AD).
Bingbing Song +10 more
wiley +1 more source
Neuronal senescence‐like states arise from convergent intrinsic and disease‐associated stressors and are linked to persistent dysfunction, SASP‐like signaling, and altered glial interactions. Because no single marker is definitive in post‐mitotic neurons, multimarker and context‐dependent frameworks are required to define their role in ...
Miraj Ud Din Momand +2 more
wiley +1 more source
AL Amyloidosis Presenting as Heart Failure: A Case Report and Review of Literature
Restrictive cardiomyopathy secondary to cardiac amyloidosis is an underdiagnosed cause of heart failure, and it is associated with significant morbidity and mortality.
Kumar R. +3 more
doaj +1 more source
Integrated Engineering of CAR‐T Cells for Solid Tumours
Solid tumours pose multifactorial barriers including antigen heterogeneity, immunosuppressive microenvironment, and poor T‐cell trafficking, limiting CAR‐T efficacy compared to hematologic malignancies. Integrated engineering strategies are essential, combining logic‐gated receptors for precision, metabolic‐epigenetic reprogramming for resilience, and ...
Chao Yang +5 more
wiley +1 more source
Serum amyloidosis: a cardiac amyloidosis
Jeremy A Slivnick +3 more
openaire +2 more sources
Introduction: Systemic amyloidosis is a condition where amyloid proteins accumulate in organs and tissues, causing multisystem dysfunction. Its presentation often overlaps with other conditions like lymphoproliferative disorders and multiple myeloma (MM).
Naciye Nur Tozluklu +3 more
doaj +1 more source
Aims The study aims to systematically assess the diagnostic performance of cardiac magnetic resonance (CMR) and nuclear scintigraphy (index tests) for the diagnosis and differentiation of subtypes of cardiac amyloidosis.
Jack Brownrigg +3 more
doaj +1 more source

