Results 11 to 20 of about 1,329,719 (361)
Transthyretin cardiac amyloidosis
Cardiovascular Research, 2022 Transthyretin cardiac amyloidosis (ATTR-CA) is an increasingly recognized cause of heart failure (HF) and mortality worldwide. Advances in non-invasive diagnosis, coupled with the development of effective treatments, have shifted ATTR-CA from a rare and ...
A. Porcari, M. Fontana, J. Gillmore
semanticscholar +5 more sources
Methodist DeBakey Cardiovascular Journal, 2022 Cardiac amyloidosis (CA) is a restrictive cardiomyopathy with a traditionally poor prognosis. Until recently, CA treatment options were limited and consisted predominantly of managing symptoms and disease-related complications.
Lily K. Stern, J. Patel
semanticscholar +4 more sources
Circulation, 2012 Cardiac involvement can be found in all types of amyloidosis, but is most frequent in AL amyloidosis. Severity of cardiac infiltration is by far the most relevant prognostic determinant. Once the heart is affected, amyloidosis carries a poor prognosis.
Candida Cristina Quarta +2 more
+8 more sources
Cardiac Amyloidosis in a Horse [PDF]
Journal of Veterinary Internal Medicine, 2003 Yvette S. Nout +4 more
openalex +4 more sources
Clinical Medicine, 2018 Systemic amyloidosis comprises an uncommon group of disorders caused by the extracellular deposition of misfolded proteins in various organs. Cardiac amyloid deposition, causing an infiltrative/restrictive cardiomyopathy, is a frequent feature of amyloidosis and a major determinant of survival.
Martinez-Naharro, A +2 more
+8 more sources
Heart Views, 2021 Amyloidosis represents a heterogeneous group of disorders caused by amyloid fibril deposition in the extracellular space in different organs. Among the many types of amyloidosis cardiac involvement occurs almost exclusively with immunoglobulin light chain amyloidosis (AL amyloidosis) or transthyretin amyloidosis (ATTR amyloidosis). When present cardiac
Salah Elbdri, Rachel Hajar
openaire +6 more sources
Heart Failure Clinics, 2022 Amyloid deposits are defined by their tinctorial properties. Under the light microscope amyloid deposits are eosinophilic and amorphous when stained with hematoxylin and eosin. With Congo red staining the deposits are positive and under polarized light will exhibit green birefringence.
T, Tadokoro +3 more
openaire +4 more sources
Tc-99m labelled bone scintigraphy in suspected cardiac amyloidosis
European Heart Journal, 2023 Aims To perform evaluation of widely embraced bone scintigraphy-based non-biopsy diagnostic criteria (NBDC) for ATTR amyloid cardiomyopathy (ATTR-CM) in clinical practice, and to refine serum free light chain (sFLC) ratio cut-offs that reliably exclude ...
M. Rauf +38 more
semanticscholar +1 more source
eJHaem, 2022 The causal protein of amyloid light‐chain (AL) amyloidosis is a monoclonal immunoglobulin free light chain (mFLC), which must be quantified in the serum for patient diagnosis and monitoring.
Hajer Abroud +18 more
doaj +1 more source