Results 11 to 20 of about 1,876,979 (380)

Early Extracorporeal CPR for Refractory Out-of-Hospital Cardiac Arrest.

New England Journal of Medicine, 2023
BACKGROUND Extracorporeal cardiopulmonary resuscitation (CPR) restores perfusion and oxygenation in a patient who does not have spontaneous circulation. The evidence with regard to the effect of extracorporeal CPR on survival with a favorable neurologic ...
Martje M. Suverein, T. Delnoij, R. Lorusso, G. J. Brandon Bravo Bruinsma, L. Otterspoor, Carlos V Elzo Kraemer, A. Vlaar, J. J. van der Heijden, E. Scholten, C. D. den Uil, T. Jansen, B. van den Bogaard, Marijn Kuijpers, K. Lam, J. M. Montero Cabezas, A. Driessen, S. Rittersma, Bram G. A. D. H. Heijnen, Dinis Dos Reis Miranda, G. Bleeker, Jesse de Metz, R. Hermanides, Jorge E. López Matta, S. Eberl, D. Donker, R. V. van Thiel, S. Akin, Oene VAN MEER, J. Henriques, K. Bokhoven, Loes Mandigers, J. Bunge, M. E. Bol, B. Winkens, B. Essers, P. Weerwind, J. Maessen, M. V. D. van de Poll   +37 more
semanticscholar   +1 more source

Hypothermia versus Normothermia after Out-of-Hospital Cardiac Arrest

New England Journal of Medicine, 2021
BACKGROUND: Targeted temperature management is recommended for patients after cardiac arrest, but the supporting evidence is of low certainty. METHODS: In an open-label trial with blinded assessment of outcomes, we randomly assigned 1900 adults with coma
J. Dankiewicz, T. Cronberg, G. Lilja, J. Jakobsen, Helena Levin, S. Ullén, C. Rylander, M. Wise, M. Oddo, A. Cariou, J. Bělohlávek, J. Hovdenes, M. Saxena, H. Kirkegaard, P. Young, P. Pelosi, C. Storm, F. Taccone, M. Joannidis, C. Callaway, G. Eastwood, Matt Morgan, P. Nordberg, D. Erlinge, A. Nichol, M. Chew, J. Hollenberg, M. Thomas, J. Bewley, K. Sweet, A. Grejs, S. Christensen, M. Haenggi, Anja Levis, A. Lundin, J. Düring, S. Schmidbauer, Thomas R. Keeble, G. Karamasis, C. Schrag, Edith Faessler, O. Šmíd, M. Otáhal, M. Maggiorini, P. D. Wendel Garcia, P. Jaubert, J. Cole, M. Solař, O. Borgquist, C. Leithner, Samia Abed-Maillard, L. Navarra, M. Annborn, J. Undén, I. Brunetti, Akil Awad, Peter Mcguigan, Roy Bjørkholt Olsen, T. Cassina, P. Vignon, Halvor Langeland, T. Lange, H. Friberg, N. Nielsen   +63 more
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Effect of Intra-arrest Transport, Extracorporeal Cardiopulmonary Resuscitation, and Immediate Invasive Assessment and Treatment on Functional Neurologic Outcome in Refractory Out-of-Hospital Cardiac Arrest: A Randomized Clinical Trial.

Journal of the American Medical Association (JAMA), 2022
Importance Out-of-hospital cardiac arrest (OHCA) has poor outcome. Whether intra-arrest transport, extracorporeal cardiopulmonary resuscitation (ECPR), and immediate invasive assessment and treatment (invasive strategy) is beneficial in this setting ...
J. Bělohlávek, J. Šmalcová, D. Rob, O. Franěk, O. Šmíd, Milana Pokorná, J. Horák, V. Mrázek, T. Kovárník, D. Zemánek, A. Král, S. Havranek, P. Kaválková, Lucie Kompelentova, Helena Tomková, Alan Mejstrik, J. Valášek, D. Peřan, J. Pekara, J. Rulíšek, M. Balík, M. Huptych, J. Jarkovský, J. Malík, A. Valerianova, F. Mlejnský, Petr Kolouch, P. Havránková, D. Romportl, A. Komárek, A. Linhart   +30 more
semanticscholar   +1 more source

Brain injury after cardiac arrest: pathophysiology, treatment, and prognosis

Intensive Care Medicine, 2021
Post-cardiac arrest brain injury (PCABI) is caused by initial ischaemia and subsequent reperfusion of the brain following resuscitation. In those who are admitted to intensive care unit after cardiac arrest, PCABI manifests as coma, and is the main cause
C. Sandroni, T. Cronberg, M. Sekhon
semanticscholar   +1 more source

Oxygen Targets in Comatose Survivors of Cardiac Arrest.

New England Journal of Medicine, 2022
BACKGROUND The appropriate oxygenation target for mechanical ventilation in comatose survivors of out-of-hospital cardiac arrest is unknown. METHODS In this randomized trial with a 2-by-2 factorial design, we randomly assigned comatose adults with out ...
H. Schmidt, J. Kjaergaard, C. Hassager, Simon Mølstrøm, J. Grand, B. Borregaard, Laust E Roelsgaard Obling, S. Venø, L. Sarkisian, D. Mamaev, L. Jensen, B. Nyholm, D. Høfsten, J. Josiassen, J. H. Thomsen, J. Thune, M. Lindholm, M. A. Stengaard Meyer, M. Winther-Jensen, Marc Sørensen, M. Frydland, R. Beske, R. Frikke-Schmidt, S. Wiberg, S. Boesgaard, Vibeke Lind Jørgensen, J. Møller   +26 more
semanticscholar   +1 more source

Blood-Pressure Targets in Comatose Survivors of Cardiac Arrest.

New England Journal of Medicine, 2022
BACKGROUND Evidence to support the choice of blood-pressure targets for the treatment of comatose survivors of out-of-hospital cardiac arrest who are receiving intensive care is limited.
J. Kjaergaard, J. Møller, H. Schmidt, J. Grand, Simon Mølstrøm, B. Borregaard, S. Venø, L. Sarkisian, D. Mamaev, L. Jensen, B. Nyholm, D. Høfsten, J. Josiassen, J. H. Thomsen, J. Thune, L. Obling, M. Lindholm, M. Frydland, M. Meyer, M. Winther-Jensen, R. Beske, R. Frikke-Schmidt, S. Wiberg, S. Boesgaard, S. A. Madsen, V. Jørgensen, C. Hassager   +26 more
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Racial and Ethnic Differences in Bystander CPR for Witnessed Cardiac Arrest.

New England Journal of Medicine, 2022
BACKGROUND Differences in the incidence of cardiopulmonary resuscitation (CPR) provided by bystanders contribute to survival disparities among persons with out-of-hospital cardiac arrest.
R. A. Garcia, J. Spertus, S. Girotra, B. Nallamothu, K. Kennedy, Bryan McNally, Khadijah K. Breathett, Marina del Rios, C. Sasson, P. Chan   +9 more
semanticscholar   +1 more source

The global survival rate among adult out-of-hospital cardiac arrest patients who received cardiopulmonary resuscitation: a systematic review and meta-analysis

Critical Care, 2020
Background To quantitatively summarize the available epidemiological evidence on the survival rate of out-of-hospital cardiac arrest (OHCA) patients who received cardiopulmonary resuscitation (CPR).
Shijiao Yan, Y. Gan, Nan Jiang, Rixing Wang, Yunqiang Chen, Zhiqian Luo, Q. Zong, Song Chen, C. Lv   +8 more
semanticscholar   +1 more source

In-hospital cardiac arrest: the state of the art

Critical Care, 2022
In-hospital cardiac arrest (IHCA) is associated with a high risk of death, but mortality rates are decreasing. The latest epidemiological and outcome data from several cardiac arrest registries are helping to shape our understanding of IHCA.
J. Penketh, J. Nolan
semanticscholar   +1 more source

Effect of dapagliflozin on ventricular arrhythmias, resuscitated cardiac arrest, or sudden death in DAPA-HF

European Heart Journal, 2021
Aims The aim of this study was to examine the effect of dapagliflozin on the incidence of ventricular arrhythmias and sudden death in patients with heart failure and reduced ejection fraction (HFrEF). Methods and results In a post hoc analysis of DAPA-HF,
J. Curtain, K. Docherty, P. Jhund, M. Petrie, S. Inzucchi, L. Køber, M. Kosiborod, F. Martinez, P. Ponikowski, M. Sabatine, O. Bengtsson, A. Langkilde, M. Sjöstrand, S. Solomon, J. McMurray   +14 more
semanticscholar   +1 more source